Proteomic analysis of hepatic effects of phenobarbital in mice with humanized liver

R: A Language and Environment for Statistical Computing

R Core Team (2000) · doi:10.32614/r.manuals · Cited by 355,706 · see citing works

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

Cox, J., & Mann, M. (2008) · Nature Biotechnology · doi:10.1038/nbt.1511 · Cited by 14,855 · see citing works

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

Gu, Z., Eils, R., & Schlesner, M. (2016) · Bioinformatics · doi:10.1093/bioinformatics/btw313 · Cited by 10,122 · see citing works

Universal sample preparation method for proteome analysis

Wiśniewski, J. R., Zougman, A., Nagaraj, N., & Mann, M. (2009) · Nature Methods · doi:10.1038/nmeth.1322 · Cited by 8,352 · see citing works

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

Cox, J., Neuhauser, N., Michalski, A., Scheltema, R. A., Olsen, J. V., & Mann, M. (2011) · Journal of Proteome Research · doi:10.1021/pr101065j · Cited by 5,349 · see citing works

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

Tyanova, S., Temu, T., & Cox, J. (2016) · Nature Protocols · doi:10.1038/nprot.2016.136 · Cited by 4,691 · see citing works

UpSetR: an R package for the visualization of intersecting sets and their properties

Conway, J. R., Lex, A., & Gehlenborg, N. (2017) · Bioinformatics · doi:10.1093/bioinformatics/btx364 · Cited by 3,586 · see citing works

Organoid Models and Applications in Biomedical Research

Xinaris, C., Brizi, V., & Remuzzi, G. (2015) · The Nephron journals/Nephron journals · doi:10.1159/000433566 · Cited by 3,517 · see citing works

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology · doi:10.1007/s00204-013-1078-5 · Cited by 1,280 · see citing works

pcaMethods—a bioconductor package providing PCA methods for incomplete data

Stacklies, W., Redestig, H., Scholz, M., Walther, D., & Selbig, J. (2007) · Bioinformatics · doi:10.1093/bioinformatics/btm069 · Cited by 1,156 · see citing works

Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice

Azuma, H., Paulk, N., Ranade, A., Dorrell, C., Al-Dhalimy, M., Ellis, E., Strom, S., Kay, M. A., Finegold, M., & Grompe, M. (2007) · Nature Biotechnology · doi:10.1038/nbt1326 · Cited by 835 · see citing works

Identification of a Novel Human Constitutive Androstane Receptor (CAR) Agonist and Its Use in the Identification of CAR Target Genes

Maglich, J. M., Parks, D. J., Moore, L. B., Collins, J. L., Goodwin, B. J., Billin, A. N., Stoltz, C. M., Kliewer, S. A., Lambert, M. H., Willson, T. M., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300138200 · Cited by 420 · see citing works

WNT/β-catenin signaling in the development of liver cancers

He, S., & Tang, S. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110851 · Cited by 356 · see citing works

Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator

Elcombe, C. R., Peffer, R. C., Wolf, D. C., Bailey, J. P., Bars, R., Bell, D., Cattley, R. C., Ferguson, S., Geter, D. R., Goetz, A. K., et al. (2013) · Critical Reviews in Toxicology · doi:10.3109/10408444.2013.835786 · Cited by 264 · see citing works

Role of CAR and PXR in xenobiotic sensing and metabolism

Wang, Y., Ong, S. S., Chai, S. C., & Chen, T. (2012) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425255.2012.685237 · Cited by 247 · see citing works

Proteomics Quality Control: Quality Control Software for MaxQuant Results

Bielow, C., Mastrobuoni, G., & Kempa, S. (2015) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5b00780 · Cited by 198 · see citing works

Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling

Mutoh, S., Sobhany, M., Moore, R., Perera, L., Pedersen, L. G., Sueyoshi, T., & Negishi, M. (2013) · Science Signaling · doi:10.1126/scisignal.2003705 · Cited by 197 · see citing works

Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of β-catenin-mutated mouse liver tumors

Aydinlik, H., Nguyen, T. D., Moennikes, O., Buchmann, A., & Schwarz, M. (2001) · Oncogene · doi:10.1038/sj.onc.1204982 · Cited by 164 · see citing works

C‐Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia†

Blanco‐Bose, W. E., Murphy, M. J., Ehninger, A., Offner, S., Dubey, C., Huang, W., Moore, D. D., & Trumpp, A. (2008) · Hepatology · doi:10.1002/hep.22475 · Cited by 138 · see citing works

Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes

Wegler, C., Gaugaz, F. Z., Andersson, T. B., Wiśniewski, J. R., Busch, D., Gröer, C., Oswald, S., Norén, A., Weiss, F., Hammer, H., et al. (2017) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.7b00364 · Cited by 121 · see citing works

Chimeric mice with humanized liver

Katoh, M., Tateno, C., Yoshizato, K., & Yokoi, T. (2007) · Toxicology · doi:10.1016/j.tox.2007.11.012 · Cited by 87 · see citing works

Testing for induction of DNA synthesis in human hepatocyte primary cultures by rat liver tumor promoters.

Parzefall, W., Erber, E., Sedivy, R., & Schulte‐Hermann, R. (1991) · PubMed · Cited by 87 · see citing works

HCOP: a searchable database of human orthology predictions

Eyre, T. A., Wright, M. W., Lush, M. J., & Bruford, E. A. (2006) · Briefings in Bioinformatics · doi:10.1093/bib/bbl030 · Cited by 86 · see citing works

The xenobiotic receptors PXR and CAR in liver physiology, an update

Cai, X., Young, G. M., & Xie, W. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2021.166101 · Cited by 84 · see citing works

Human Hepatocytes Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogen Sodium Phenobarbital in an In Vivo Study Using a Chimeric Mouse with Humanized Liver

Yamada, T., Okuda, Y., Kushida, M., Sumida, K., Takeuchi, H., Nagahori, H., Fukuda, T., Lake, B. G., Cohen, S. M., & Kawamura, S. (2014) · Toxicological Sciences · doi:10.1093/toxsci/kfu173 · Cited by 80 · see citing works

Regulation of gene expression by CAR: an update

Kobayashi, K., Hashimoto, M., Honkakoski, P., & Negishi, M. (2015) · Archives of Toxicology · doi:10.1007/s00204-015-1522-9 · Cited by 80 · see citing works

Phenobarbital Confers its Diverse Effects by Activating the Orphan Nuclear Receptor Car

Kodama, S., & Negishi, M. (2006) · Drug Metabolism Reviews · doi:10.1080/03602530600569851 · Cited by 77 · see citing works

Human relevance of rodent liver tumour formation by constitutive androstane receptor (CAR) activators

Lake, B. G. (2018) · Toxicology Research · doi:10.1039/c8tx00008e · Cited by 66 · see citing works

PCB 153, a Non-dioxin–like Tumor Promoter, Selects for β-Catenin (Catnb)–Mutated Mouse Liver Tumors

Strathmann, J., Schwarz, M., Tharappel, J. C., Glauert, H. P., Spear, B. T., Robertson, L. W., Appel, K. E., & Buchmann, A. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl041 · Cited by 61 · see citing works

Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes

Gährs, M., Roos, R. J., Andersson, P. L., & Schrenk, D. (2013) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2013.05.034 · Cited by 61 · see citing works

Sex difference in the proliferative response of mouse hepatocytes to treatment with the CAR ligand, TCPOBOP

Columbano, A. (2003) · Carcinogenesis · doi:10.1093/carcin/bgg063 · Cited by 60 · see citing works

Review Article: Paradoxical Effects of Phenobarbital on Mouse Hepatocarcinogenesis

Lee, G. (2000) · Toxicologic Pathology · doi:10.1177/019262330002800201 · Cited by 58 · see citing works

The Connection of Azole Fungicides with Xeno-Sensing Nuclear Receptors, Drug Metabolism and Hepatotoxicity

Marx‐Stoelting, P., Knebel, C., & Braeuning, A. (2020) · Cells · doi:10.3390/cells9051192 · Cited by 54 · see citing works

Proteome wide screening using peptide affinity capture

Poetz, O., Hoeppe, S., Templin, M. F., Stoll, D., & Joos, T. O. (2009) · PROTEOMICS · doi:10.1002/pmic.200800842 · Cited by 53 · see citing works

Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice

Marx‐Stoelting, P., Ganzenberg, K., Knebel, C., Schmidt, F., Rieke, S., Hammer, H., Schmidt, F. F., Poetz, O., Schwarz, M., & Braeuning, A. (2017) · Archives of Toxicology · doi:10.1007/s00204-016-1925-2 · Cited by 50 · see citing works

Chimeric Mice with Humanized Livers: A Unique Tool for in Vivo and in Vitro Enzyme Induction Studies

Kakuni, M., Yamasaki, C., Tachibana, A., Yoshizane, Y., Ishida, Y., & Tateno, C. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms15010058 · Cited by 49 · see citing works

An update on the constitutive androstane receptor (CAR)

Molnár, F., Küblbeck, J., Jyrkkärinne, J., Prantner, V., & Honkakoski, P. (2013) · Drug metabolism and drug interactions · doi:10.1515/dmdi-2013-0009 · Cited by 45 · see citing works

Proteus : an R package for downstream analysis of MaxQuant outputPreprint

Gierliński, M., Gastaldello, F., Cole, C., & Barton, G. J. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/416511 · Cited by 44 · see citing works

Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR)

Yamada, T., Cohen, S. M., & Lake, B. G. (2021) · Critical Reviews in Toxicology · doi:10.1080/10408444.2021.1939654 · Cited by 41 · see citing works

Gender-Specific Interplay of Signaling through β-Catenin and CAR in the Regulation of Xenobiotic-Induced Hepatocyte Proliferation

Braeuning, A., Heubach, Y., Knorpp, T., Kowalik, M. A., Templin, M., Columbano, A., & Schwarz, M. (2011) · Toxicological Sciences · doi:10.1093/toxsci/kfr166 · Cited by 40 · see citing works

Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes

Haines, C. E., Elcombe, B. M., Chatham, L. R., Vardy, A., Higgins, L. G., Elcombe, C. R., & Lake, B. G. (2018) · Toxicology · doi:10.1016/j.tox.2018.02.001 · Cited by 29 · see citing works

Propagation of Human Hepatocytes in uPA/SCID Mice: Producing Chimeric Mice with Humanized Liver

Ohshita, H., & Tateno, C. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-6506-9_6 · Cited by 28 · see citing works

Tumor promotion and inhibition by phenobarbital in livers of conditional Apc-deficient mice

Braeuning, A., Gavrilov, A., Geissler, M., Wenz, C., Colnot, S., Templin, M. F., Metzger, U., Römer, M., Zell, A., & Schwarz, M. (2016) · Archives of Toxicology · doi:10.1007/s00204-016-1667-1 · Cited by 23 · see citing works

Is the question of phenobarbital as potential liver cancer risk factor for humans really resolved?

Braeuning, A., & Schwarz, M. (2016) · Archives of Toxicology · doi:10.1007/s00204-016-1712-0 · Cited by 23 · see citing works

Nuclear Receptor-Mediated Hepatomegaly and Liver Regeneration: An Update

Zhao, P., Fan, S., Gao, Y., Huang, M., & Bi, H. (2022) · Drug Metabolism and Disposition · doi:10.1124/dmd.121.000454 · Cited by 20 · see citing works

Cross-species comparison of CAR-mediated procarcinogenic key events in a 3D liver microtissue model

Plummer, S., Beaumont, B., Wallace, S., Ball, G., Wright, J., McInnes, L., Currie, R., Peffer, R., & Cowie, D. (2019) · Toxicology Reports · doi:10.1016/j.toxrep.2019.09.010 · Cited by 20 · see citing works

Successful Engraftment of Human Hepatocytes in uPA-SCID and FRG® KO Mice

Foquet, L., Wilson, E. M., Verhoye, L., Grompe, M., Leroux-Roels, G. G., Bial, J., & Meuleman, P. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-6506-9_8 · Cited by 18 · see citing works

High Frequency of β-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist

Mattu, S., Saliba, C., Sulas, P., Zavattari, P., Perra, A., Kowalik, M. A., Monga, S. P., & Columbano, A. (2018) · American Journal Of Pathology · doi:10.1016/j.ajpath.2018.07.022 · Cited by 16 · see citing works

Comparison of the Hepatic Effects of Phenobarbital in Chimeric Mice Containing Either Rat or Human Hepatocytes With Humanized Constitutive Androstane Receptor and Pregnane X Receptor Mice

Yamada, T., Ôhara, A., Ozawa, N., Maeda, K., Kondo, M., Okuda, Y., Abe, J., Cohen, S. M., & Lake, B. G. (2020) · Toxicological Sciences · doi:10.1093/toxsci/kfaa125 · Cited by 16 · see citing works

Optimal selection of epitopes for TXP-immunoaffinity mass spectrometry

Planatscher, H., Supper, J., Poetz, O., Stoll, D., Joos, T. O., Templin, M. F., & Zell, A. (2010) · Algorithms for Molecular Biology · doi:10.1186/1748-7188-5-28 · Cited by 16 · see citing works

Model Systems for Understanding Mechanisms of Nongenotoxic Carcinogenesis: Response.

Braeuning, A., Henderson, C. J., Wolf, C. R., & Schwarz, M. (2015) · PubMed · doi:10.1093/toxsci/kfv175 · Cited by 16 · see citing works

Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters

Chow, E., Wang, J. Z. Y., Quach, H., Tang, H., Evans, D. C., Li, A. P., Silva, J. M., & Pang, K. (2016) · Drug Metabolism And Disposition · doi:10.1124/dmd.116.070060 · Cited by 13 · see citing works

Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice

Bernhard, A., Rasinger, J. D., Wisløff, H., Kolbjørnsen, Ø., Myrmel, L. S., Berntssen, M. H. G., Lundebye, A., Ørnsrud, R., & Madsen, L. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.06.005 · Cited by 11 · see citing works

From the Editor's Desk, Editor's Highlights, Letters to the Editor

Yamada, T., Cohen, S. M., & Lake, B. G. (2015) · Toxicological Sciences · doi:10.1093/toxsci/kfv186 · Cited by 11 · see citing works

Characterization of hepatic zonation in mice by mass-spectrometric and antibody-based proteomics approaches

Kling, S., Lang, B., Hammer, H., Naboulsi, W., Sprenger, H., Frenzel, F., Poetz, O., Schwarz, M., Braeuning, A., & Templin, M. F. (2021) · Biological Chemistry · doi:10.1515/hsz-2021-0314 · Cited by 6 · see citing works

Induction and repression effects on CYP and transporter protein abundance by azole mixture uptake in rat liver

Hammer, H., Schmidt, F., Heise, T., Knebel, C., Dabrowski, A., Planatscher, H., Kneuer, C., Marx‐Stoelting, P., & Poetz, O. (2020) · EXCLI journal · doi:10.17179/excli2020-2311 · Cited by 6 · see citing works

Metabolism-Disrupting Chemicals Affecting the Liver: Screening, Testing, and Molecular Pathway Identification

Fritsche, K., Ziková, A., Marx‐Stoelting, P., & Braeuning, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032686 · Cited by 42 · see citing works

Increased Cell Proliferation as a Key Event in Chemical Carcinogenesis: Application in an Integrated Approach for the Testing and Assessment of Non-Genotoxic Carcinogenesis

Strupp, C., Corvaro, M., Cohen, S. M., Corton, J. C., Ogawa, K., Richert, L., & Jacobs, M. N. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713246 · Cited by 39 · see citing works

The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation

Yamada, T., Cohen, S. M., & Lake, B. G. (2025) · Critical Reviews in Toxicology · doi:10.1080/10408444.2025.2513332 · Cited by 14 · see citing works

Multi-tissue proteogenomic analysis for mechanistic toxicology studies in non-model species

Lin, M. S., Varunjikar, M. S., Lie, K. K., Søfteland, L., Dellafiora, L., Ørnsrud, R., Sanden, M., Berntssen, M. H. G., Dorne, J. L. C. M., Bafna, V., et al. (2023) · Environment International · doi:10.1016/j.envint.2023.108309 · Cited by 7 · see citing works

Mode of action analysis for fluxapyroxad-induced rat liver tumour formation: evidence for activation of the constitutive androstane receptor and assessment of human relevance

Goettel, M., Werner, C., Honarvar, N., Gröters, S., Fegert, I., Haines, C., Chatham, L. R., Vardy, A., & Lake, B. G. (2024) · Toxicology · doi:10.1016/j.tox.2024.153828 · Cited by 6 · see citing works

Energy-Dense High-Fat/High-Sucrose Diet to Induce Type 2 Diabetes Mellitus in BALB/c Mice Without Genetic Modifications and Chemical Agents

Diaz-Herreros, A. N., Valdez-Guerrero, A. S., Cancino‐Díaz, J. C., Sánchez‐Torres, L. E., Gómez‐Chávez, F., Arellano-Mendoza, M. G., Cach, F. T., & Cancino-Diaz, M. E. (2026) · Biology · doi:10.3390/biology15020109 · Cited by 4 · see citing works

The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals

Henderson, C. J., McLaren, A. W., MacLeod, A. K., Lin, D., Cameron, A., Chatham, L. R., Moggs, J. G., Iñesta-Vaquera, F., Thomson, J. P., Meehan, R. R., et al. (2025) · Archives of Toxicology · doi:10.1007/s00204-025-03982-9 · Cited by 3 · see citing works

An evaluation of the human relevance of the hepatocellular tumors observed in mice treated with synthetic fungicide, pyridachlometyl, based on mode of action

Kawamoto, K., Shimotsuma, Y., Maeda, K., Matsunaga, K., Asano, H., Cohen, S. M., & Yamada, T. (2025) · Archives of Toxicology · doi:10.1007/s00204-025-04099-9 · Cited by 3 · see citing works

Response to Letter to the Editor from Drs. van Kesteren, Pronk, Heusinkveld, Luijten and Hakkert concerning Yamada et al. (2021): Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Crit. Rev. Toxicol. Vol. 51: 373-394.

Yamada, T., Cohen, S. M., & Lake, B. G. (2022) · Critical Reviews in Toxicology · doi:10.1080/10408444.2022.2101915 · Cited by 2 · see citing works

Constitutive Androstane Receptor Regulates Bile Acid Homeostasis and Metabolism During Liver Regeneration

Zhou, W., Chembazhi, U. V., Huang, J., Bangru, S., Dean, A. E., Asokakumar, A., Kalsotra, A., Rudnick, D. A., & Anakk, S. (2026) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2026.101858

Mode of action analysis for mouse liver tumor formation by MGK-264 and human relevance

Yano, J., Kawamoto, K., Shimotsuma, Y., Ogata, K., Matsunaga, K., Abe, J., Fukunaga, S., Osimitz, T. G., Lake, B. G., & Asano, H. (2025) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2025.105929

Response to the Letter from Professor C. R. Wolf and colleagues concerning CRT, 55: 549–586, 2025: The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome-proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation

Yamada, T., Cohen, S. M., & Lake, B. G. (2025) · Critical Reviews in Toxicology · doi:10.1080/10408444.2025.2601198

Comparison of the Hepatic Effects of Phenobarbital in Chimeric Mice Containing Either Rat or Human Hepatocytes With Humanized Constitutive Androstane Receptor and Pregnane X Receptor Mice

Yamada, T., Ôhara, A., Ozawa, N., Maeda, K., Kondo, M., Okuda, Y., Abe, J., Cohen, S. M., & Lake, B. G. (2020) · Toxicological Sciences · doi:10.1093/toxsci/kfaa125 · Cited by 16 · see citing works

Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes

Haines, C. E., Elcombe, B. M., Chatham, L. R., Vardy, A., Higgins, L. G., Elcombe, C. R., & Lake, B. G. (2018) · Toxicology · doi:10.1016/j.tox.2018.02.001 · Cited by 29 · see citing works

Application of humanized mice to toxicology studies: Evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR)

Yamada, T. (2021) · Journal of Toxicologic Pathology · doi:10.1293/tox.2021-0027 · Cited by 12 · see citing works

Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.

Luisier, R., Lempiäinen, H., Scherbichler, N., Braeuning, A., Geissler, M., Dubost, V., Müller, A., Scheer, N., Chibout, S., Hara, H., et al. (2014) · Toxicological Sciences · doi:10.1093/toxsci/kfu038 · Cited by 70 · see citing works

Phenobarbital-Mediated Tumor Promotion in Transgenic Mice with Humanized CAR and PXR

Braeuning, A., Gavrilov, A., Brown, S., Wolf, C. R., Henderson, C. J., & Schwarz, M. (2014) · Toxicological Sciences · doi:10.1093/toxsci/kfu099 · Cited by 57 · see citing works