Wang, Guan

Chemical reprogramming of human somatic cells to pluripotent stem cells.

Guan, J., Wang, G., Wang, J., Zhang, Z., Fu, Y., Cheng, L., Meng, G., Lyu, Y., Zhu, J., Li, Y., et al. (2022) · Nature

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 388

Development of small-molecule tropomyosin receptor kinase (TRK) inhibitors for NTRK fusion cancers

Jiang, T., Wang, G., Liu, Y., Feng, L., Wang, M., Liu, J., Chen, Y., & Ouyang, L. (2021) · Acta Pharmaceutica Sinica B

Cancer Mechanisms and TherapyLung Cancer Treatments and Mutations

Cited by 157

Highly efficient and rapid generation of human pluripotent stem cells by chemical reprogramming.

Liuyang, S., Wang, G., Wang, Y., He, H., Lyu, Y., Cheng, L., Yang, Z., Guan, J., Fu, Y., Zhu, J., et al. (2023) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 136

Targeting Lysosomal Degradation Pathways: New Strategies and Techniques for Drug Discovery

Pei, J., Wang, G., Feng, L., Zhang, J., Jiang, T., Sun, Q., & Ouyang, L. (2021) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsAutophagy in Disease and Therapy

Cited by 124

Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy

Tan, L., Zhang, J., Wang, Y., Wang, X., Wang, Y., Zhang, Z., Shuai, W., Wang, G., Chen, J., Wang, C., et al. (2022) · Journal of Medicinal Chemistry

Lung Cancer Treatments and MutationsHER2/EGFR in Cancer Research

Cited by 88

Development of covalent inhibitors: Principle, design, and application in cancer

Zheng, L., Li, Y., Wu, D., Xiao, H., Zheng, S., Wang, G., & Sun, Q. (2023) · MedComm – Oncology

Click Chemistry and ApplicationsHeterocyclic Compound Synthesis and Bioactivity

Cited by 71

Small molecules targeting protein–protein interactions for cancer therapy

Wu, D., Li, Y., Zheng, L., Xiao, H., Ouyang, L., Wang, G., & Sun, Q. (2023) · Acta Pharmaceutica Sinica B

Protein Degradation and InhibitorsComputational Drug Discovery Methods

Cited by 71

Dual‐target inhibitors of bromodomain and extra‐terminal proteins in cancer: A review from medicinal chemistry perspectives

Feng, L., Wang, G., Chen, Y., He, G., Liu, B., Liu, J., Chiang, C., & Ouyang, L. (2022) · Medicinal Research Reviews

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

Cited by 65

Development of inhibitors targeting glycogen synthase kinase-3β for human diseases: Strategies to improve selectivity

Wei, J., Wang, J., Zhang, J., Yang, J., Wang, G., & Wang, Y. (2022) · European Journal of Medicinal Chemistry

Wnt/β-catenin signaling in development and cancerProtein Kinase Regulation and GTPase Signaling

Cited by 42

Design, synthesis and biological evaluation of coumarin derivatives as novel acetylcholinesterase inhibitors that attenuate H2O2-induced apoptosis in SH-SY5Y cells

Yao, D., Wang, J., Wang, G., Jiang, Y., Shang, L., Zhao, Y., Huang, J., Yang, S., Wang, J., & Yu, Y. (2016) · Bioorganic Chemistry

Cholinesterase and Neurodegenerative DiseasesHeterocyclic Compound Synthesis and Bioactivity

Cited by 30

Comparison of the Effects of Intermittent Energy Restriction and Continuous Energy Restriction among Adults with Overweight or Obesity: An Overview of Systematic Reviews and Meta-Analyses

Wang, J., Wang, F., Chen, H., Liu, L., Zhang, S., Luo, W., Wang, G., & Hu, X. (2022) · Nutrients

Dietary Effects on HealthDiet and metabolism studies

Cited by 17

Integrating multiple omics data for the discovery of potential Beclin-1 interactions in breast cancer

Chen, Y., Wang, X., Wang, G., Li, Z., Wang, J., Huang, L., Qin, Z., Yuan, X., Cheng, Z., Zhang, S., et al. (2017) · Molecular BioSystems

Breast Cancer Treatment StudiesGene expression and cancer classification

Cited by 14