Wang, Xin

The consensus molecular subtypes of colorectal cancer

Guinney, J., Dienstmann, R., Wang, X., de Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., et al. (2015) · Nature Medicine

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

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Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions

De Sousa E Melo, F., Wang, X., Jansen, M., Fessler, E., Trinh, A., de Rooij, L. P. M. H., de Jong, J. H., de Boer, O. J., van Leersum, R., Bijlsma, M. F., et al. (2013) · Nature Medicine

Genetic factors in colorectal cancerColorectal Cancer Treatments and Studies

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DeepCC: a novel deep learning-based framework for cancer molecular subtype classification

Gao, F., Wang, W., Tan, M., Zhu, L., Zhang, Y., Fessler, E., Vermeulen, L., & Wang, X. (2019) · Oncogenesis

Gene expression and cancer classificationBioinformatics and Genomic Networks

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Practical and robust identification of molecular subtypes in colorectal cancer by immunohistochemistry

Trinh, A., Trumpi, K., De Sousa E Melo, F., Wang, X., de Jong, J. H., Fessler, E., Kuppen, P. J. K., Reimers, M. S., Swets, M., Koopman, M., et al. (2017) · Clinical Cancer Research

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

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TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype

Fessler, E., Drost, J., van Hooff, S. R., Linnekamp, J. F., Wang, X., Jansen, M., De Sousa E Melo, F., Prasetyanti, P. R., IJspeert, J. E., Franitza, M., et al. (2016) · EMBO Molecular Medicine

TGF-β signaling in diseasesColorectal Cancer Treatments and Studies

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mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-dependent Foxk1 Phosphorylation

He, L., Gomes, A. P., Wang, X., Yoon, S. O., Lee, G., Nagiec, M. J., Cho, S., Chavez, A., Islam, T., Yu, Y., et al. (2018) · Molecular Cell

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

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A Multimodal Knowledge-enhanced Whole-slide Pathology Foundation Model

Xu, Y., Wang, Y., Zhou, F., Ma, J., Jin, C., Yang, S., Li, J., Zhang, Z., Zhao, C., Zhou, H., et al. (2024) · arXiv

AI in cancer detectionRadiomics and Machine Learning in Medical Imaging

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Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2

Mai, S., Zhu, X., Wan, E. Y. C., Wu, S., Yonathan, J. N., Wang, J., Li, Y., Ma, J. Y. W., Zuo, B., Tse, D. Y.-Y., et al. (2022) · Development

Ocular Disorders and TreatmentsRetinal Development and Disorders

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A Citrate Synthase Splice Variant Rewires the TCA Cycle to Promote Colorectal Cancer Progression

Cheung, J. C. T., Ng, L. W., Zhu, Z., Chen, B., Li, S., Xu, M., Ding, X., Pu, D., Hu, Y., Ren, Y., et al. (2025) · Cancer Research

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

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