Cheng, Yan

DNA Repair Pathways in Cancer Therapy and Resistance

Li, L.-Y., Guan, Y.-D., Chen, X.-S., Yang, J.-M., & Cheng, Y. (2021) · Frontiers in Pharmacology

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 383

HAMdb: a database of human autophagy modulators with specific pathway and disease information

Wang, N.-N., Dong, J., Zhang, L., Ouyang, D., Cheng, Y., Chen, A. F., Lu, A.-P., & Cao, D.-S. (2018) · Journal of Cheminformatics

Autophagy in Disease and TherapyComputational Drug Discovery Methods

Cited by 83

UCH-L1-mediated Down-regulation of Estrogen Receptor α Contributes to Insensitivity to Endocrine Therapy for Breast Cancer

Chen, X.-S., Wang, K.-S., Guo, W., Li, L.-Y., Yu, P., Sun, X.-Y., Wang, H.-Y., Guan, Y.-D., Tao, Y.-G., Ding, B.-N., et al. (2020) · Theranostics

Estrogen and related hormone effectsBreast Cancer Treatment Studies

Cited by 58

Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway

Jiang, S.-L., Guan, Y.-D., Chen, X.-S., Ge, P., Wang, X.-L., Lao, Y.-Z., Xiao, S.-S., Zhang, Y., Yang, J.-M., Xu, X.-J., et al. (2019) · Acta Pharmacologica Sinica

Autophagy in Disease and TherapyNatural product bioactivities and synthesis

Cited by 37

Combined treatment of mitoxantrone sensitizes breast cancer cells to rapalogs through blocking eEF-2K-mediated activation of Akt and autophagy

Guan, Y., Jiang, S., Ye, W., Ren, X., Wang, X., Zhang, Y., Yin, M., Wang, K., Tao, Y., Yang, J., et al. (2020) · Cell Death & Disease

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 34

Harnessing artificial intelligence to identify Bufalin as a molecular glue degrader of estrogen receptor alpha

Jiang, S., Liu, K., Jiang, T., Li, H., Wei, X., Wan, X., Zhong, C., Gong, R., Chen, Z., Zou, C., et al. (2025) · Nature Communications

Protein Degradation and InhibitorsComputational Drug Discovery Methods

Cited by 23

Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids

Zeng, L., Zou, Q., Huang, P., Xiong, L., Cheng, Y., Chen, Q., Li, Y., He, H., Yi, W., & Wei, W. (2021) · Biomedicine & Pharmacotherapy

Photodynamic Therapy Research StudiesParathyroid Disorders and Treatments

Cited by 23

A multi-scale systems pharmacology approach uncovers the anti-cancer molecular mechanism of Ixabepilone

Cao, D.-S., Jiang, S.-L., Guan, Y.-D., Chen, X.-S., Zhang, L.-X., Zhang, Y., Chen, A. F., Yang, J.-M., & Cheng, Y. (2020) · European Journal of Medicinal Chemistry

Computational Drug Discovery MethodsCell death mechanisms and regulation

Cited by 16