Nelson, David L.

Initial sequencing and analysis of the human genome

International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature

Genomics and Phylogenetic StudiesGenetic Associations and Epidemiology

Cited by 24,216

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

Verkerk, A. J. M. H., Pieretti, M., Sutcliffe, J. S., Fu, Y.-H., Kuhl, D. P. A., Pizzuti, A., Reiner, O., Richards, S., Victoria, M. F., Zhang, F., et al. (1991) · Cell

Genetics and Neurodevelopmental DisordersGenomic variations and chromosomal abnormalities

Cited by 3,481

Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox

Fu, Y.-H., Kuhl, D. P. A., Pizzuti, A., Pieretti, M., Sutcliffe, J. S., Richards, S., Verkert, A. J. M. H., Holden, J. J. A., Fenwick, R. G., Warren, S. T., et al. (1991) · Cell

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 2,080

Absence of expression of the FMR-1 gene in fragile X syndrome

Pieretti, M., Zhang, F., Fu, Y.-H., Warren, S. T., Oostra, B. A., Caskey, C. T., & Nelson, D. L. (1991) · Cell

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 1,476

Evolutionary and biomedical insights from the rhesus macaque genome.

Gibbs, R. A., Rogers, J., Katze, M. G., Bumgarner, R., Weinstock, G. M., Mardis, E. R., Remington, K. A., Strausberg, R. L., Venter, J. C., Wilson, R. K., et al. (2007) · Science

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 1,403

The DNA sequence of the human X chromosome

Ross, M. T., Grafham, D. V., Coffey, A. J., Scherer, S., McLay, K., Muzny, D., Platzer, M., Howell, G. R., Burrows, C., Bird, C. P., et al. (2005) · Nature

Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesChromosomal and Genetic Variations

Cited by 1,129

DNA methylation represses FMR-1 transcription in fragile X syndrome

Sutcliffe, J. S., Nelson, D. L., Zhang, F., Pieretti, M., Caskey, C. T., Saxe, D., & Warren, S. T. (1992) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation

Cited by 680

Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome

Hinds, H. L., Ashley, C. T., Sutcliffe, J. S., Nelson, D. L., Warren, S. T., Housman, D. E., & Schalling, M. (1993) · Nature Genetics

Genetics and Neurodevelopmental DisordersWilliams Syndrome Research

Cited by 396

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

de Vrij, F. M. S., Levenga, J., van der Linde, H. C., Koekkoek, S. K., De Zeeuw, C. I., Nelson, D. L., Oostra, B. A., & Willemsen, R. (2008) · Neurobiology of Disease

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 313

AGG interruptions within the maternal FMR1 gene reduce the risk of offspring with fragile X syndrome

Yrigollen, C. M., Durbin-Johnson, B., Gane, L., Nelson, D. L., Hagerman, R., Hagerman, P. J., & Tassone, F. (2012) · Genetics in Medicine

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 179

Fragile X-related proteins regulate mammalian circadian behavioral rhythms

Zhang, J., Fang, Z., Jud, C., Vansteensel, M. J., Kaasik, K., Lee, C. C., Albrecht, U., Tamanini, F., Meijer, J. H., Oostra, B. A., et al. (2008) · The American Journal of Human Genetics

Circadian rhythm and melatoninGenetics and Neurodevelopmental Disorders

Cited by 131

Altered Hippocampal Synaptic Plasticity in the Fmr1 Gene Family Knockout Mouse Models

Zhang, J., Hou, L., Klann, E., & Nelson, D. L. (2009) · Journal of Neurophysiology

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 126

Selective deletion of astroglial FMRP dysregulates glutamate transporter GLT1 and contributes to fragile X syndrome phenotypes in vivo.

Higashimori, H., Schin, C. S., Chiang, M. S. R., Morel, L., Shoneye, T. A., Nelson, D. L., & Yang, Y. (2016) · Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 105

Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene.

Spencer, C. M., Graham, D. F., Yuva-Paylor, L. A., Nelson, D. L., & Paylor, R. (2008) · Behavioral Neuroscience

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 91

Retrotransposon activation contributes to fragile X premutation rCGG-mediated neurodegeneration

Tan, H., Qurashi, A., Poidevin, M., Nelson, D. L., Li, H., & Jin, P. (2012) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 78

Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes

Musumeci, S. A., Calabrese, G., Bonaccorso, C. M., D'Antoni, S., Brouwer, J. R., Bakker, C. E., Elia, M., Ferri, R., Nelson, D. L., Oostra, B. A., et al. (2007) · Experimental Neurology

Genetics and Neurodevelopmental DisordersEpilepsy research and treatment

Cited by 70

Reversal of sensorimotor gating abnormalities in Fmr1 knockout mice carrying a human Fmr1 transgene.

Paylor, R., Yuva-Paylor, L. A., Nelson, D. L., & Spencer, C. M. (2008) · Behavioral Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 46

Intragenic probe used for diagnostics in fragile X families

Verkerk, A. J. M. H., De Vries, B. B. A., Niermeijer, M. F., Fu, Y., Nelson, D. L., Warren, S. T., Majoor‐Krakauer, D. F., Halley, D. J. J., & Oostra, B. A. (1992) · American Journal of Medical Genetics

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

Cited by 17