Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes

Fmr1 knockout mice: A model to study fragile X mental retardation

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Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits

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The FMR–1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

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The Fragile X Syndrome Protein FMRP Associates with BC1 RNA and Regulates the Translation of Specific mRNAs at Synapses

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The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein.

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Evidence that fragile X mental retardation protein is a negative regulator of translation

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Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes.

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Analysis of neocortex in three males with the Fragile X syndrome

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Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP

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From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome

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The fragile X mental retardation protein inhibits translation via interacting with mRNA

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The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals

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Prevalence of carriers of premutation-size alleles of the FMRI gene--and implications for the population genetics of the fragile X syndrome.

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Fragile X mice develop sensory hyperreactivity to auditory stimuli

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The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development

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Audiogenic Seizures Susceptibility in Transgenic Mice with Fragile X Syndrome

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Premutation and intermediate-size FMR1 alleles in 10 572 males from the general population: loss of an AGG interruption is a late event in the generation of fragile X syndrome alleles

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(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features

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Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain

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Epilepsy in fragile X syndrome

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The fragile X mental retardation protein is associated with ribosomes

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Epilepsy and EEG Findings in Males with Fragile X Syndrome

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A phenotypic and molecular characterization of the <i>fmr1‐tm1Cgr</i> Fragile X mouse

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Decreased GABAA receptor expression in the seizure-prone fragile X mouse

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Immunocytochemical and Biochemical Characterization of FMRP, FXR1P, and FXR2P in the Mouse

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Expression profiling suggests underexpression of the GABAA receptor subunit δ in the fragile X knockout mouse model

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Visual Experience Regulates Transient Expression and Dendritic Localization of Fragile X Mental Retardation Protein

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Neuropathologic findings associated with seizures in FVB mice.

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Untitled work

Irwin (2001) · doi:10.1002/1096-8628(20010115)98:2

Rescue of fragile X syndrome phenotypes in <i>Fmr1</i> KO mice by the small-molecule PAK inhibitor FRAX486

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Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes

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Increased GABAB Receptor-Mediated Signaling Reduces the Susceptibility of Fragile X Knockout Mice to Audiogenic Seizures

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Matrix metalloproteinase-9 deletion rescues auditory evoked potential habituation deficit in a mouse model of Fragile X Syndrome

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Fragile X mental retardation protein replacement restores hippocampal synaptic function in a mouse model of fragile X syndrome

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Audiogenic Seizures in theFmr1Knock-Out Mouse Are Induced byFmr1Deletion in Subcortical, VGlut2-Expressing Excitatory Neurons and Require Deletion in the Inferior Colliculus

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Establishment of Reporter Lines for Detecting Fragile X Mental Retardation (FMR1) Gene Reactivation in Human Neural Cells

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Fragile X mental retardation protein (FMRP) interacting proteins exhibit different expression patterns during development

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Resilience to audiogenic seizures is associated with p-ERK1/2 dephosphorylation in the subiculum of Fmr1 knockout mice

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Abnormal neuronal morphology and neurochemistry in the auditory brainstem of Fmr1 knockout rats.

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Abnormal development of auditory responses in the inferior colliculus of a mouse model of Fragile X Syndrome

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Reactivation of FMR1 gene expression is a promising strategy for fragile X syndrome therapy

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A single early-life seizure results in long-term behavioral changes in the adult Fmr1 knockout mouse

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Gene therapy using human FMRP isoforms driven by the human FMR1 promoter rescues fragile X syndrome mouse deficits

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Evaluation of lorcaserin as an anticonvulsant in juvenile Fmr1 knockout mice

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Fragile X mental retardation protein (FMRP) and metabotropic glutamate receptor subtype 5 (mGlu5) control stress granule formation in astrocytes

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From wings to whiskers to stem cells: why every model matters in fragile X syndrome research

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Development of a Quantitative FMRP Assay for Mouse Tissue Applications

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Spatially coordinated heterochromatinization of distal short tandem repeats in fragile X syndromePreprint

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