Manji, Husseini K.

The FKBP5 gene in depression and treatment response – an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) cohort

Lekman, M., Laje, G., Charney, D., Rush, A. J., Wilson, A. F., Sorant, A. J. M., Lipsky, R., Wisniewski, S. R., Manji, H., McMahon, F. J., et al. (2008) · Biological Psychiatry

Treatment of Major DepressionGenetic Associations and Epidemiology

Cited by 284

Increased Anterior Cingulate Cortical Activity in Response to Fearful Faces: A Neurophysiological Biomarker that Predicts Rapid Antidepressant Response to Ketamine

Salvadore, G., Cornwell, B. R., Colon-Rosario, V., Coppola, R., Grillon, C., Zarate, C. A., & Manji, H. K. (2009) · Biological Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 277

Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder

Duncan, W. C., Sarasso, S., Ferrarelli, F., Selter, J., Riedner, B. A., Hejazi, N. S., Yuan, P., Brutsche, N., Manji, H. K., Tononi, G., et al. (2013) · International Journal of Neuropsychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 256

Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

Manji, H. K., & Lenox, R. H. (1999) · Biological Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 241

How can drug discovery for psychiatric disorders be improved?

Agid, Y., Buzsáki, G., Diamond, D. M., Frackowiak, R., Giedd, J., Girault, J.-A., Grace, A., Lambert, J. J., Manji, H., Mayberg, H., et al. (2007) · Nature Reviews Drug Discovery

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 240

A Longitudinal Study of the Effects of Lithium Treatment on Prefrontal and Subgenual Prefrontal Gray Matter Volume in Treatment-Responsive Bipolar Disorder Patients

Moore, G. J., Cortese, B. M., Glitz, D. A., Zajac-Benitez, C., Quiroz, J. A., Uhde, T. W., Drevets, W. C., & Manji, H. K. (2009) · The Journal of Clinical Psychiatry

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 234

Elevated Serotonin Transporter Binding in Major Depressive Disorder Assessed Using Positron Emission Tomography and [11C]DASB; Comparison with Bipolar Disorder

Cannon, D. M., Ichise, M., Rollis, D., Klaver, J. M., Gandhi, S. K., Charney, D. S., Manji, H. K., & Drevets, W. C. (2007) · Biological Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 219

Serotonin transporter binding in bipolar disorder assessed using [11C] DASB and positron emission tomography

Cannon, D. M., Ichise, M., Fromm, S. J., Nugent, A. C., Rollis, D., Gandhi, S. K., Klaver, J. M., Charney, D. S., Manji, H. K., & Drevets, W. C. (2006) · Biological Psychiatry

Bipolar Disorder and TreatmentNeurotransmitter Receptor Influence on Behavior

Cited by 197

Rapid Onset of Antidepressant Action: A New Paradigm in the Research and Treatment of Major Depressive Disorder

Machado-Vieira, R., Salvadore, G., Luckenbaugh, D. A., Manji, H. K., & Zarate, C. A. (2008) · The Journal of Clinical Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 195

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

Shaltiel, G., Maeng, S., Malkesman, O., Pearson, B., Schloesser, R. J., Tragon, T., Rogawski, M., Gasior, M., Luckenbaugh, D., Chen, G., et al. (2008) · Molecular Psychiatry

Bipolar Disorder and TreatmentNeuroscience and Neuropharmacology Research

Cited by 173

The Role of the Tripartite Glutamatergic Synapse in the Pathophysiology and Therapeutics of Mood Disorders

Machado-Vieira, R., Manji, H. K., & Zarate, C. A. (2009) · The Neuroscientist

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 171

Neural Correlates of Rapid Antidepressant Response to Ketamine in Treatment-Resistant Unipolar Depression: A Preliminary Positron Emission Tomography Study

Carlson, P. J., Diazgranados, N., Nugent, A. C., Ibrahim, L., Luckenbaugh, D. A., Brutsche, N., Herscovitch, P., Manji, H. K., Zarate, C. A., & Drevets, W. C. (2013) · Biological Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 168

Modulation of Synaptic Plasticity by Antimanic Agents: The Role of AMPA Glutamate Receptor Subunit 1 Synaptic Expression

Du, J., Gray, N. A., Falke, C. A., Chen, W., Yuan, P., Szabo, S. T., Einat, H., & Manji, H. K. (2004) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchBipolar Disorder and Treatment

Cited by 157

Brain-Derived Neurotrophic Factor and Initial Antidepressant Response to an N-Methyl-D-Aspartate Antagonist

Machado-Vieira, R., Yuan, P., Brutsche, N., DiazGranados, N., Luckenbaugh, D., Manji, H. K., & Zarate, C. A. (2009) · The Journal of Clinical Psychiatry

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 155

Protein Kinase C Inhibitors: Rationale for Use and Potential in the Treatment of Bipolar Disorder

Zarate, C. A., & Manji, H. K. (2009) · CNS Drugs

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 122

Sustained Low-Grade Pro-inflammatory State in Unmedicated, Remitted Women with Major Depressive Disorder as Evidenced by Elevated Serum Levels of the Acute Phase Proteins C-reactive Protein and Serum Amyloid A

Kling, M. A., Alesci, S., Csako, G., Costello, R., Luckenbaugh, D. A., Bonne, O., Duncko, R., Drevets, W. C., Manji, H. K., Charney, D. S., et al. (2007) · Biological Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 111

Mobile and pervasive computing technologies and the future of Alzheimer’s clinical trials

Doraiswamy, P. M., Narayan, V. A., & Manji, H. K. (2018) · npj Digital Medicine

Mobile Health and mHealth ApplicationsDementia and Cognitive Impairment Research

Cited by 97

Cerebrospinal Fluid Metabolome in Mood Disorders-Remission State has a Unique Metabolic Profile

Kaddurah-Daouk, R., Yuan, P., Boyle, S. H., Matson, W., Wang, Z., Zeng, Z. B., Zhu, H., Dougherty, G. G., Yao, J. K., Chen, G., et al. (2012) · Scientific Reports

Tryptophan and brain disordersTreatment of Major Depression

Cited by 76

Reverse translational strategies for developing animal models of bipolar disorder

Malkesman, O., Austin, D. R., Chen, G., & Manji, H. K. (2009) · Disease Models & Mechanisms

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 70

Investigating the neuroimmunogenic architecture of schizophrenia

Birnbaum, R., Jaffe, A. E., Chen, Q., Shin, J. H., BrainSeq Consortium, Schubert, C. R., O'Donnell, P., Quan, J., Wendland, J. R., Xi, H. S., et al. (2018) · Molecular Psychiatry

Tryptophan and brain disordersSchizophrenia research and treatment

Cited by 67

Enhancing AMPA to NMDA throughput as a convergent mechanism for antidepressant action

Du, J., Machado-Vieira, R., Maeng, S., Martinowich, K., Manji, H. K., & Zarate, C. A. (2006) · Drug Discovery Today: Therapeutic Strategies

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 64

Roles of p75NTR, Long-Term Depression, and Cholinergic Transmission in Anxiety and Acute Stress Coping

Martinowich, K., Schloesser, R. J., Lu, Y., Jimenez, D. V., Paredes, D., Greene, J. S., Greig, N. H., Manji, H. K., & Lu, B. (2012) · Biological Psychiatry

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 48

Timing is everything: does the robust upregulation of noradrenergically regulated plasticity genes underlie the rapid antidepressant effects of sleep deprivation?

Payne, J. L., Quiroz, J. A., Zarate, C. A., & Manji, H. K. (2002) · Biological Psychiatry

Treatment of Major DepressionSleep and Wakefulness Research

Cited by 46

Verapamil augmentation of lithium treatment improves outcome in mania unresponsive to lithium alone: preliminary findings and a discussion of therapeutic mechanisms

Mallinger, A. G., Thase, M. E., Haskett, R., Buttenfield, J., Luckenbaugh, D. A., Frank, E., Kupfer, D. J., & Manji, H. K. (2008) · Bipolar Disorders

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 44