Gandy, Sam

Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice

Audrain, M., Haure‐Mirande, J., Mleczko, J., Wang, M., Griffin, J. K., St George‐Hyslop, P. H., Fraser, P., Zhang, B., Gandy, S., & Ehrlich, M. E. (2021) · Alzheimer's & Dementia

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 65

nELAV Proteins Alteration in Alzheimer's Disease Brain: A Novel Putative Target for Amyloid-β Reverberating on AβPP Processing

Amadio, M., Pascale, A., Wang, J., Ho, L., Quattrone, A., Gandy, S., Haroutunian, V., Racchi, M., & Pasinetti, G. M. (2009) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

Apolipoprotein E ϵ4 and fatal cerebral amyloid angiopathy associated with dementia pugilistica

Jordan, B. D., Kanik, A. B., Horwich, M. S., Sweeney, D., Relkin, N. R., Petito, C. K., & Gandy, S. (1995) · Annals of Neurology

Intracerebral and Subarachnoid Hemorrhage ResearchTraumatic Brain Injury Research

Cited by 55

APOE Genotype Results in Differential Effects on the Peripheral Clearance of Amyloid-β42 in APOE Knock-in and Knock-out Mice

Sharman, M. J., Morici, M., Hone, E., Berger, T., Taddei, K., Martins, I. J., Lim, W. L. F., Singh, S., Wenk, M. R., Ghiso, J., et al. (2010) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 54

New developments of biofluid‐based biomarkers for routine diagnosis and disease trajectories in frontotemporal dementia

del Campo, M., Zetterberg, H., Gandy, S., Onyike, C. U., Oliveira, F., Udeh‐Momoh, C., Lleó, A., Teunissen, C. E., & Pijnenburg, Y. (2022) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 52

Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

Sekiya, M., Wang, M., Fujisaki, N., Sakakibara, Y., Quan, X., Ehrlich, M. E., De Jager, P. L., Bennett, D. A., Schadt, E. E., Gandy, S., et al. (2018) · Genome Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 38

miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease

Readhead, B., Haure-Mirande, J.-V., Mastroeni, D., Audrain, M., Fanutza, T., Kim, S. H., Blitzer, R. D., Gandy, S., Dudley, J. T., & Ehrlich, M. E. (2020) · Acta Neuropathologica

Alzheimer's disease research and treatmentsMicroRNA in disease regulation

Cited by 37

Profiling Brain and Plasma Lipids in Human APOE ε2, ε3, and ε4 Knock-in Mice Using Electrospray Ionization Mass Spectrometry

Sharman, M. J., Shui, G., Fernandis, A. Z., Lim, W. L. F., Berger, T., Hone, E., Taddei, K., Martins, I. J., Ghiso, J., Buxbaum, J. D., et al. (2010) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsMetabolomics and Mass Spectrometry Studies

Cited by 35

The isotropic fractionator provides evidence for differential loss of hippocampal neurons in two mouse models of Alzheimer’s disease

Brautigam, H., Steele, J. W., Westaway, D., Fraser, P. E., George-Hyslop, P. H. S., Gandy, S., Hof, P. R., & Dickstein, D. L. (2012) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 31

APOE ε4 and bapineuzumab: Infusing pharmacogenomics into Alzheimer disease therapeutics

Kaufer, D., & Gandy, S. (2009) · Neurology

Alzheimer's disease research and treatmentsBacterial biofilms and quorum sensing

Cited by 21

Genetic architecture of plasma Alzheimer disease biomarkers

Bradley, J., Gorijala, P., Schindler, S. E., Sung, Y. J., Ances, B., the Alzheimer’s Disease Neuroimaging Initiative, T. H. C. P., Ertekin-Taner, N., Younkin, S., Golde, T., Price, N., et al. (2023) · Human Molecular Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 20

miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer’s amyloidopathy

Gandy, S., & Ehrlich, M. E. (2023) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 11

Molecular Networks and Key Regulators of the Dysregulated Neuronal System in Alzheimer’s Disease

Wang, M., Li, A., Sekiya, M., Beckmann, N. D., Quan, X., Schrode, N., Fernando, M. B., Yu, A., Zhu, L., Cao, J., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 6

Alzheimer mutant speeds APP transport

Gandy, S., & Ehrlich, M. E. (2021) · Journal of Experimental Medicine

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 3