McDonald, Timothy J.

The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells

Oram, R. A., Jones, A. G., Besser, R. E. J., Knight, B. A., Shields, B. M., Brown, R. J., Hattersley, A. T., & McDonald, T. J. (2014) · Diabetologia

Diabetes and associated disordersPancreatic function and diabetes

Cited by 298

Systematic population screening, using biomarkers and genetic testing, identifies 2.5% of the U.K. pediatric diabetes population with monogenic diabetes

Shepherd, M., Shields, B., Hammersley, S., Hudson, M., McDonald, T. J., Colclough, K., Oram, R. A., Knight, B., Hyde, C., Cox, J., et al. (2016) · Diabetes Care

Diabetes and associated disordersPancreatic function and diabetes

Cited by 236

Initial splanchnic extraction of ingested glucose in normal man

Radziuk, J., McDonald, T. J., Rubenstein, D., & Dupre, J. (1978) · Metabolism

Pancreatic function and diabetesDiabetes Management and Research

Cited by 207

Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes

Thomas, N. J., Lynam, A. L., Hill, A. V., Weedon, M. N., Shields, B. M., Oram, R. A., McDonald, T. J., Hattersley, A. T., & Jones, A. G. (2019) · Diabetologia

Diabetes and associated disordersDiabetes Management and Research

Cited by 183

Population-based assessment of a biomarker-based screening pathway to aid diagnosis of monogenic diabetes in young-onset patients

Shields, B. M., Shepherd, M., Hudson, M., McDonald, T. J., Colclough, K., Peters, J., Knight, B., Hyde, C., Ellard, S., Pearson, E. R., et al. (2017) · Diabetes Care

Diabetes and associated disordersPancreatic function and diabetes

Cited by 151

Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors

Oram, R. A., McDonald, T. J., Shields, B. M., Hudson, M. M., Shepherd, M. H., Hammersley, S., Pearson, E. R., Hattersley, A. T., & on behalf of the UNITED Team (2015) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 133

Latent autoimmune diabetes of adults (LADA) is likely to represent a mixed population of autoimmune (type 1) and nonautoimmune (type 2) diabetes

Jones, A. G., McDonald, T. J., Shields, B. M., Hagopian, W., & Hattersley, A. T. (2021) · Diabetes Care

Diabetes and associated disordersDiabetes Management and Research

Cited by 122

Clinical Impact of Residual C-Peptide Secretion in Type 1 Diabetes on Glycemia and Microvascular Complications

Jeyam, A., Colhoun, H., McGurnaghan, S., Blackbourn, L., McDonald, T. J., Palmer, C. N. A., McKnight, J. A., Strachan, M. W. J., Patrick, A. W., Chalmers, J., et al. (2021) · Diabetes Care

Diabetes Management and ResearchDiabetes and associated disorders

Cited by 118

Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models

Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., et al. (2023) · Nature Biotechnology

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 111

Islet Autoantibody Standardization Program 2018 workshop: interlaboratory comparison of glutamic acid decarboxylase autoantibody assay performance

Lampasona, V., Pittman, D. L., Williams, A. J., Achenbach, P., Schlosser, M., Akolkar, B., Winter, W. E., Laboratories, P., Watson, K., Weets, I., et al. (2019) · Clinical Chemistry

Diabetes and associated disordersClinical Laboratory Practices and Quality Control

Cited by 103

Predicting and elucidating the etiology of fatty liver disease: a machine learning modeling and validation study in the IMI DIRECT cohorts

Atabaki-Pasdar, N., Ohlsson, M., Viñuela, A., Frau, F., Pomares-Millan, H., Haid, M., Jones, A. G., Thomas, E. L., Koivula, R. W., Kurbasic, A., et al. (2020) · PLOS Medicine

Liver Disease Diagnosis and TreatmentAlcohol Consumption and Health Effects

Cited by 97

Urine C-peptide creatinine ratio is a noninvasive alternative to the mixed-meal tolerance test in children and adults with type 1 diabetes

Besser, R. E. J., Ludvigsson, J., Jones, A. G., McDonald, T. J., Shields, B. M., Knight, B. A., & Hattersley, A. T. (2011) · Diabetes Care

Diabetes and associated disordersPancreatic function and diabetes

Cited by 82

Development and validation of multivariable clinical diagnostic models to identify type 1 diabetes requiring rapid insulin therapy in adults aged 18-50 years

Lynam, A., McDonald, T., Hill, A., Dennis, J., Oram, R., Pearson, E., Weedon, M., Hattersley, A., Owen, K., Shields, B., et al. (2019) · BMJ Open

Diabetes and associated disordersDiabetes Management and Research

Cited by 72

Random non‐fasting C–peptide: bringing robust assessment of endogenous insulin secretion to the clinic

Hope, S. V., Knight, B. A., Shields, B. M., Hattersley, A. T., McDonald, T. J., & Jones, A. G. (2016) · Diabetic Medicine

Diabetes Management and ResearchPancreatic function and diabetes

Cited by 68

Pre-and/or postnatal protein restriction developmentally programs affect and risk assessment behaviors in adult male rats

Reyes-Castro, L. A., Rodriguez, J. S., Rodríguez-González, G. L., Chavira, R., Bautista, C. J., McDonald, T. J., Nathanielsz, P. W., & Zambrano, E. (2012) · Behavioural Brain Research

Birth, Development, and HealthMaternal Mental Health During Pregnancy and Postpartum

Cited by 44

Validation of a single-sample urinary C-peptide creatinine ratio as a reproducible alternative to serum C-peptide in patients with Type 2 diabetes

Bowman, P., McDonald, T. J., Shields, B. M., Knight, B. A., & Hattersley, A. T. (2012) · Diabetic Medicine

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 40