Levine, Mark

Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention

Padayatty, S. J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J.-H., Chen, S., Corpe, C., Dutta, A., Dutta, S. K., et al. (2003) · Journal of the American College of Nutrition

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 1,949

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues

Chen, Q., Espey, M. G., Krishna, M. C., Mitchell, J. B., Corpe, C. P., Buettner, G. R., Shacter, E., & Levine, M. (2005) · Proceedings of the National Academy of Sciences

Vitamin C and Antioxidants ResearchCancer and biochemical research

Cited by 1,075

Vitamin C pharmacokinetics: Implications for oral and intravenous use

Padayatty, S. J., Sun, H., Wang, Y., Riordan, H. D., Hewitt, S. M., Katz, A., Wesley, R. A., & Levine, M. (2004) · Annals of Internal Medicine

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 992

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

Chen, Q., Espey, M. G., Sun, A. Y., Pooput, C., Kirk, K. L., Krishna, M. C., Khosh, D. B., Drisko, J., & Levine, M. (2008) · Proceedings of the National Academy of Sciences

Vitamin C and Antioxidants ResearchCancer and biochemical research

Cited by 854

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

Chen, Q., Espey, M. G., Sun, A. Y., Lee, J.-H., Krishna, M. C., Shacter, E., Choyke, P. L., Pooput, C., Kirk, K. L., Buettner, G. R., et al. (2007) · Proceedings of the National Academy of Sciences

Vitamin C and Antioxidants ResearchRedox biology and oxidative stress

Cited by 676

Criteria and recommendations for vitamin C intake

Levine, M. (1999) · JAMA

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 559

High-Dose Parenteral Ascorbate Enhanced Chemosensitivity of Ovarian Cancer and Reduced Toxicity of Chemotherapy

Ma, Y., Chapman, J., Levine, M., Polireddy, K., Drisko, J., & Chen, Q. (2014) · Science Translational Medicine

Vitamin C and Antioxidants ResearchOvarian cancer diagnosis and treatment

Cited by 501

A new recommended dietary allowance of vitamin C for healthy young women

Levine, M., Wang, Y., Padayatty, S. J., & Morrow, J. (2001) · Proceedings of the National Academy of Sciences

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 496

Phase I clinical trial of i.v. ascorbic acid in advanced malignancy

Hoffer, L. J., Levine, M., Assouline, S., Melnychuk, D., Padayatty, S. J., Rosadiuk, K., Rousseau, C., Robitaille, L., & Miller, W. H. (2008) · Annals of Oncology

Vitamin C and Antioxidants ResearchComplementary and Alternative Medicine Studies

Cited by 375

Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival

Sotiriou, S., Gispert, S., Cheng, J., Wang, Y., Chen, A., Hoogstraten-Miller, S., Miller, G. F., Kwon, O., Levine, M., Guttentag, S. H., et al. (2002) · Nature Medicine

Vitamin C and Antioxidants ResearchAmino Acid Enzymes and Metabolism

Cited by 367

Vitamin C: A concentration-function approach yields pharmacology and therapeutic discoveries

Levine, M., Padayatty, S. J., & Espey, M. G. (2011) · Advances in Nutrition

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 357

Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

Du, J., Martin, S. M., Levine, M., Wagner, B. A., Buettner, G. R., Wang, S.-H., Taghiyev, A. F., Du, C., Knudson, C. M., & Cullen, J. J. (2010) · Clinical Cancer Research

Vitamin C and Antioxidants ResearchPancreatic and Hepatic Oncology Research

Cited by 316

Ascorbic acid and dehydroascorbic acid measurements in human plasma and serum

Dhariwal, K., Hartzell, W., & Levine, M. (1991) · The American Journal of Clinical Nutrition

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 262

Effect of antioxidant supplementation on ozone-induced lung injury in human subjects

SAMET, J. M., HATCH, G. E., HORSTMAN, D., STECK-SCOTT, S., ARAB, L., BROMBERG, P. A., LEVINE, M., MCDONNELL, W. F., & DEVLIN, R. B. (2001) · American Journal of Respiratory and Critical Care Medicine

Antioxidant Activity and Oxidative StressAir Quality and Health Impacts

Cited by 164

Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice

Corpe, C. P., Tu, H., Eck, P., Wang, J., Faulhaber-Walter, R., Schnermann, J., Margolis, S., Padayatty, S., Sun, H., Wang, Y., et al. (2010) · Journal of Clinical Investigation

Vitamin C and Antioxidants ResearchIron Metabolism and Disorders

Cited by 162

Determination of optimal vitamin C requirements in humans

Levine, M., Dhariwal, K., Welch, R., Wang, Y., & Park, J. (1995) · The American Journal of Clinical Nutrition

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 149

Systematic Review of Intravenous Ascorbate in Cancer Clinical Trials

Nauman, G., Gray, J. C., Parkinson, R., Levine, M., & Paller, C. J. (2018) · Antioxidants

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 107

6-Bromo-6-deoxy-l-ascorbic Acid

Corpe, C. P., Lee, J.-H., Kwon, O., Eck, P., Narayanan, J., Kirk, K. L., & Levine, M. (2005) · Journal of Biological Chemistry

Vitamin C and Antioxidants ResearchAmino Acid Enzymes and Metabolism

Cited by 95

Genetic Variation in the Sodium-dependent Vitamin C Transporters, SLC23A1, and SLC23A2 and Risk for Preterm Delivery

Erichsen, H. C., Engel, S. A. M., Eck, P. K., Welch, R., Yeager, M., Levine, M., Siega-Riz, A. M., Olshan, A. F., & Chanock, S. J. (2006) · American Journal of Epidemiology

Vitamin C and Antioxidants ResearchGenetic Associations and Epidemiology

Cited by 79

Oxalic acid excretion after intravenous ascorbic acid administration

Robitaille, L., Mamer, O. A., Miller, W. H., Levine, M., Assouline, S., Melnychuk, D., Rousseau, C., & Hoffer, L. J. (2009) · Metabolism

Vitamin C and Antioxidants ResearchKidney Stones and Urolithiasis Treatments

Cited by 67

Genetic Variation in Sodium-Dependent Vitamin C Transporters SLC23A1 and SLC23A2 and Risk of Advanced Colorectal Adenoma

Erichsen, H. C., Peters, U., Eck, P., Welch, R., Schoen, R. E., Yeager, M., Levine, M., Hayes, R. B., & Chanock, S. (2008) · Nutrition and Cancer

Genetic Associations and EpidemiologyGenetic factors in colorectal cancer

Cited by 36

Chemical Transport Knockout for Oxidized Vitamin C, Dehydroascorbic Acid, Reveals Its Functions in vivo

Tu, H., Wang, Y., Li, H., Brinster, L. R., & Levine, M. (2017) · EBioMedicine

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 35

Antitumor effect of pharmacologic ascorbate in the B16 murine melanoma model

Serrano, O. K., Parrow, N. L., Violet, P.-C., Yang, J., Zornjak, J., Basseville, A., & Levine, M. (2015) · Free Radical Biology and Medicine

Vitamin C and Antioxidants ResearchCancer and biochemical research

Cited by 29

Vitamin C and myocardial infarction: the heart of the matter3

Padayatty, S. J., & Levine, M. (2000) · The American Journal of Clinical Nutrition

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 18