Davies, Susan E.

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

Olive, K. P., Jacobetz, M. A., Davidson, C. J., Gopinathan, A., McIntyre, D., Honess, D., Madhu, B., Goldgraben, M. A., Caldwell, M. E., Allard, D., et al. (2009) · Science

Pancreatic and Hepatic Oncology ResearchHedgehog Signaling Pathway Studies

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Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

Broutier, L., Mastrogiovanni, G., Verstegen, M. M., Francies, H. E., Gavarró, L. M., Bradshaw, C. R., Allen, G. E., Arnes-Benito, R., Sidorova, O., Gaspersz, M. P., et al. (2017) · Nature Medicine

Cancer Cells and MetastasisHepatocellular Carcinoma Treatment and Prognosis

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Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology

Neuberger, J., Patel, J., Caldwell, H., Davies, S., Hebditch, V., Hollywood, C., Hubscher, S., Karkhanis, S., Lester, W., Roslund, N., et al. (2020) · Gut

Liver Disease Diagnosis and TreatmentLiver Disease and Transplantation

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Cholangiocyte organoids can repair bile ducts after transplantation in the human liver

Sampaziotis, F., Muraro, D., Tysoe, O. C., Sawiak, S., Beach, T. E., Godfrey, E. M., Upponi, S. S., Brevini, T., Wesley, B. T., Garcia-Bernardo, J., et al. (2021) · Science

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

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Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

Brunner, S. F., Roberts, N. D., Wylie, L. A., Moore, L., Aitken, S. J., Davies, S. E., Sanders, M. A., Ellis, P., Alder, C., Hooks, Y., et al. (2019) · Nature

Cancer Genomics and DiagnosticsLiver physiology and pathology

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Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease

Aravinthan, A., Scarpini, C., Tachtatzis, P., Verma, S., Penrhyn-Lowe, S., Harvey, R., Davies, S. E., Allison, M., Coleman, N., & Alexander, G. (2013) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentTelomeres, Telomerase, and Senescence

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Retraction of an interpretation

Murch, S. H., Anthony, A., Casson, D. H., Malik, M., Berelowitz, M., Dhillon, A. P., Thomson, M. A., Valentine, A., Davies, S. E., & Walker-Smith, J. A. (2004) · The Lancet

Pharmacovigilance and Adverse Drug ReactionsAutism Spectrum Disorder Research

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Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids

Sampaziotis, F., Justin, A. W., Tysoe, O. C., Sawiak, S., Godfrey, E. M., Upponi, S. S., Gieseck, R. L., de Brito, M. C., Berntsen, N. L., Gómez-Vázquez, M. J., et al. (2017) · Nature Medicine

Tissue Engineering and Regenerative MedicinePediatric Hepatobiliary Diseases and Treatments

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Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis

Mózes, F. E., Lee, J. A., Vali, Y., Alzoubi, O., Staufer, K., Trauner, M., Paternostro, R., Stauber, R. E., Holleboom, A. G., van Dijk, A.-M., et al. (2023) · The Lancet Gastroenterology & Hepatology

Liver Disease Diagnosis and TreatmentLiver Disease and Transplantation

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Colonic CD8 and γδ T-cell infiltration with epithelial damage in children with autism

Furlano, R. I., Anthony, A., Day, R., Brown, A., McGarvey, L., Thomson, M. A., Davies, S. E., Berelowitz, M., Forbes, A., Wakefield, A. J., et al. (2001) · The Journal of Pediatrics

Autism Spectrum Disorder ResearchMicroscopic Colitis

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Convergent somatic mutations in metabolism genes in chronic liver disease

Ng, S. W. K., Rouhani, F. J., Brunner, S. F., Brzozowska, N., Aitken, S. J., Yang, M., Abascal, F., Moore, L., Nikitopoulou, E., Chappell, L., et al. (2021) · Nature

Cancer Genomics and DiagnosticsLiver Disease Diagnosis and Treatment

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Acquisition of epithelial plasticity in human chronic liver disease

Gribben, C., Galanakis, V., Calderwood, A., Williams, E. C., Chazarra-Gil, R., Larraz, M., Frau, C., Puengel, T., Guillot, A., Rouhani, F. J., et al. (2024) · Nature

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

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Hepatocyte Expression of the Senescence Marker p21 Is Linked to Fibrosis and an Adverse Liver-Related Outcome in Alcohol-Related Liver Disease

Aravinthan, A., Pietrosi, G., Hoare, M., Jupp, J., Marshall, A., Verrill, C., Davies, S., Bateman, A., Sheron, N., Allison, M., et al. (2013) · PLoS ONE

Alcohol Consumption and Health EffectsLiver physiology and pathology

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RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state

Belenguer, G., Mastrogiovanni, G., Pacini, C., Hall, Z., Dowbaj, A. M., Arnes-Benito, R., Sljukic, A., Prior, N., Kakava, S., Bradshaw, C. R., et al. (2022) · Nature Communications

Liver physiology and pathologyWnt/β-catenin signaling in development and cancer

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Identification of Mutations in SLC40A1 That Affect Ferroportin Function and Phenotype of Human Ferroportin Iron Overload

Mayr, R., Griffiths, W. J. H., Hermann, M., McFarlane, I., Halsall, D. J., Finkenstedt, A., Douds, A., Davies, S. E., Janecke, A. R., Vogel, W., et al. (2011) · Gastroenterology

Iron Metabolism and DisordersNeurological diseases and metabolism

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Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis

Vacca, M., Leslie, J., Virtue, S., Lam, B. Y. H., Govaere, O., Tiniakos, D., Snow, S., Davies, S., Petkevicius, K., Tong, Z., et al. (2020) · Nature Metabolism

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

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CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection

Hoare, M., Gelson, W. T. H., Das, A., Fletcher, J. M., Davies, S. E., Curran, M. D., Vowler, S. L., Maini, M. K., Akbar, A. N., & Alexander, G. J. M. (2010) · Journal of Hepatology

Hepatitis C virus researchTelomeres, Telomerase, and Senescence

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Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression

Azzu, V., Vacca, M., Kamzolas, I., Hall, Z., Leslie, J., Carobbio, S., Virtue, S., Davies, S. E., Lukasik, A., Dale, M., et al. (2021) · Molecular Metabolism

Liver Disease Diagnosis and TreatmentCancer, Lipids, and Metabolism

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P1198 : Histological stage is relevant for risk-stratification in primary biliary cirrhosis

Carbone, M., Sharp, S. J., Heneghan, M. A., Neuberger, J. M., Hirschfield, G. M., Burroughs, A. K., Thorburn, D., Bathgate, A., Aldersley, M., Adgey, C., et al. (2015) · Journal of Hepatology

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