Kodama, Tatsuhiko

Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts

Takayanagi, H., Kim, S., Koga, T., Nishina, H., Isshiki, M., Yoshida, H., Saiura, A., Isobe, M., Yokochi, T., Inoue, J.-I., et al. (2002) · Developmental Cell

Bone Metabolism and DiseasesSignaling Pathways in Disease

Cited by 2,701

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Watanabe, M., Houten, S. M., Mataki, C., Christoffolete, M. A., Kim, B. W., Sato, H., Messaddeq, N., Harney, J. W., Ezaki, O., Kodama, T., et al. (2006) · Nature

Adipose Tissue and MetabolismDrug Transport and Resistance Mechanisms

Cited by 2,220

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

Nakashima, T., Hayashi, M., Fukunaga, T., Kurata, K., Oh-hora, M., Feng, J. Q., Bonewald, L. F., Kodama, T., Wutz, A., Wagner, E. F., et al. (2011) · Nature Medicine

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 1,778

Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction

Sato, K., Suematsu, A., Okamoto, K., Yamaguchi, A., Morishita, Y., Kadono, Y., Tanaka, S., Kodama, T., Akira, S., Iwakura, Y., et al. (2006) · The Journal of Experimental Medicine

Bone Metabolism and DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 1,554

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

Komatsu, N., Okamoto, K., Sawa, S., Nakashima, T., Oh-hora, M., Kodama, T., Tanaka, S., Bluestone, J. A., & Takayanagi, H. (2014) · Nature Medicine

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 1,153

Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

Tanaka, T., Yamamoto, J., Iwasaki, S., Asaba, H., Hamura, H., Ikeda, Y., Watanabe, M., Magoori, K., Ioka, R. X., Tachibana, K., et al. (2003) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 832

Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk

Das Pradhan, A., Glynn, R. J., Fruchart, J.-C., MacFadyen, J. G., Zaharris, E. S., Everett, B. M., Campbell, S. E., Oshima, R., Amarenco, P., Blom, D. J., et al. (2022) · New England Journal of Medicine

Lipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 749

Osteoprotection by semaphorin 3A

Hayashi, M., Nakashima, T., Taniguchi, M., Kodama, T., Kumanogoh, A., & Takayanagi, H. (2012) · Nature

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 606

Suppression of bone formation by osteoclastic expression of semaphorin 4D

Negishi-Koga, T., Shinohara, M., Komatsu, N., Bito, H., Kodama, T., Friedel, R. H., & Takayanagi, H. (2011) · Nature Medicine

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 498

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

Kubota, T., Kubota, N., Kumagai, H., Yamaguchi, S., Kozono, H., Takahashi, T., Inoue, M., Itoh, S., Takamoto, I., Sasako, T., et al. (2011) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 435

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3–kinase

Terauchi, Y., Tsuji, Y., Satoh, S., Minoura, H., Murakami, K., Okuno, A., Inukai, K., Asano, T., Kaburagi, Y., Ueki, K., et al. (1999) · Nature Genetics

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 399

The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma

Yamauchi, N., Watanabe, A., Hishinuma, M., Ohashi, K.-I., Midorikawa, Y., Morishita, Y., Niki, T., Shibahara, J., Mori, M., Makuuchi, M., et al. (2005) · Modern Pathology

Hepatocellular Carcinoma Treatment and PrognosisProteoglycans and glycosaminoglycans research

Cited by 338

The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development

Sakaki-Yumoto, M., Kobayashi, C., Sato, A., Fujimura, S., Matsumoto, Y., Takasato, M., Kodama, T., Aburatani, H., Asashima, M., Yoshida, N., et al. (2006) · Development

Developmental Biology and Gene RegulationCongenital heart defects research

Cited by 264

Purification and characterization of a bovine acetyl low density lipoprotein receptor.

Kodama, T., Reddy, P., Kishimoto, C., & Krieger, M. (1988) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 259

Dynamic Change of Chromatin Conformation in Response to Hypoxia Enhances the Expression of GLUT3 (SLC2A3) by Cooperative Interaction of Hypoxia-Inducible Factor 1 and KDM3A

Mimura, I., Nangaku, M., Kanki, Y., Tsutsumi, S., Inoue, T., Kohro, T., Yamamoto, S., Fujita, T., Shimamura, T., Suehiro, J.-I., et al. (2012) · Molecular and Cellular Biology

Cancer, Hypoxia, and MetabolismGenomics and Chromatin Dynamics

Cited by 251

Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial

Ishibashi, S., Yamashita, S., Arai, H., Araki, E., Yokote, K., Suganami, H., Fruchart, J.-C., & Kodama, T. (2016) · Atherosclerosis

Peroxisome Proliferator-Activated ReceptorsLipoproteins and Cardiovascular Health

Cited by 208

Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines

Nishida, K. M., Okada, T. N., Kawamura, T., Mituyama, T., Kawamura, Y., Inagaki, S., Huang, H., Chen, D., Kodama, T., Siomi, H., et al. (2009) · The EMBO Journal

Chromosomal and Genetic VariationsRNA Interference and Gene Delivery

Cited by 197

Involvement of specific macrophage-lineage cells surrounding arterioles in barrier and scavenger function in brain cortex.

Mato, M., Ookawara, S., Sakamoto, A., Aikawa, E., Ogawa, T., Mitsuhashi, U., Masuzawa, T., Suzuki, H., Honda, M., Yazaki, Y., et al. (1996) · Proceedings of the National Academy of Sciences

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 187

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential: A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation

Fruchart, J.-C., Santos, R. D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P. J., Ceska, R., Corsini, A., Després, J.-P., et al. (2019) · Cardiovascular Diabetology

Peroxisome Proliferator-Activated ReceptorsLipoproteins and Cardiovascular Health

Cited by 140

The Calcineurin-NFAT-Angiopoietin-2 Signaling Axis in Lung Endothelium Is Critical for the Establishment of Lung Metastases

Minami, T., Jiang, S., Schadler, K., Suehiro, J.-I., Osawa, T., Oike, Y., Miura, M., Naito, M., Kodama, T., & Ryeom, S. (2013) · Cell Reports

Angiogenesis and VEGF in CancerSignaling Pathways in Disease

Cited by 111

Transcriptome Analysis of K-877 (a Novel Selective PPARα Modulator (SPPARMα))-Regulated Genes in Primary Human Hepatocytes and the Mouse Liver

Raza-Iqbal, S., Tanaka, T., Anai, M., Inagaki, T., Matsumura, Y., Ikeda, K., Taguchi, A., Gonzalez, F. J., Sakai, J., & Kodama, T. (2015) · Journal of Atherosclerosis and Thrombosis

Peroxisome Proliferator-Activated ReceptorsDrug-Induced Hepatotoxicity and Protection

Cited by 100

Glycolaldehyde-Modified Low Density Lipoprotein Leads Macrophages to Foam Cells via the Macrophage Scavenger Receptor

Jinnouchi, Y., Sano, H., Nagai, R., Hakamata, H., Kodama, T., Suzuki, H., Yoshida, M., Ueda, S., & Horiuchi, S. (1998) · Journal of Biochemistry

Advanced Glycation End Products researchCholesterol and Lipid Metabolism

Cited by 48

Different Distribution of Pentraxin 3 and C-Reactive Protein in Coronary Atherosclerotic Plaques

Matsuura, Y., Hatakeyama, K., Imamura, T., Tsuruda, T., Shibata, Y., Kodama, T., Kitamura, K., & Asada, Y. (2012) · Journal of Atherosclerosis and Thrombosis

Biomarkers in Disease MechanismsAtherosclerosis and Cardiovascular Diseases

Cited by 31

Lessons from PROMINENT and prospects for pemafibrate

Fruchart, J.-C., Fruchart-Najib, J., Yamashita, S., Libby, P., Yokote, K., Kodama, T., Tomita, Y., Ridker, P. M., Hermans, M. P., & Zambon, A. (2024) · Cardiovascular Diabetology

Peroxisome Proliferator-Activated ReceptorsLiver Disease Diagnosis and Treatment

Cited by 16