Oostra, Ben A.

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

DIAGRAM Consortium, Dupuis, J., GIANT Consortium, Global BPgen Consortium, Anders Hamsten on behalf of Procardis Consortium, the MAGIC investigators, Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,166

The Fragile X Syndrome Protein FMRP Associates with BC1 RNA and Regulates the Translation of Specific mRNAs at Synapses

Zalfa, F., Giorgi, M., Primerano, B., Moro, A., Di Penta, A., Reis, S., Oostra, B., & Bagni, C. (2003) · Cell

Genetics and Neurodevelopmental DisordersRNA Research and Splicing

Cited by 676

A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease

Di Fonzo, A., Rohé, C. F., Ferreira, J., Chien, H. F., Vacca, L., Stocchi, F., Guedes, L., Fabrizio, E., Manfredi, M., Vanacore, N., et al. (2005) · The Lancet

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 531

A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis

Njajou, O. T., Vaessen, N., Joosse, M., Berghuis, B., van Dongen, J. W. F., Breuning, M. H., Snijders, P. J. L. M., Rutten, W. P. F., Sandkuijl, L. A., Oostra, B. A., et al. (2001) · Nature Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 492

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Consortium for Refractive Error and Myopia (CREAM), Verhoeven, V. J. M., The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Wellcome Trust Case Control Consortium 2 (WTCCC2), The Fuchs' Genetics Multi-Center Study Group, Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Höhn, R., et al. (2013) · Nature Genetics

Ophthalmology and Visual Impairment StudiesGenetic Associations and Epidemiology

Cited by 487

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

Davies, G., Armstrong, N., Bis, J. C., Bressler, J., Chouraki, V, Giddaluru, S., Hofer, E., Ibrahim-Verbaas, C. A., Kirin, M., Lahti, J., et al. (2015) · Molecular Psychiatry

Genetic Associations and EpidemiologyCognitive Abilities and Testing

Cited by 384

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

de Vrij, F. M. S., Levenga, J., van der Linde, H. C., Koekkoek, S. K., De Zeeuw, C. I., Nelson, D. L., Oostra, B. A., & Willemsen, R. (2008) · Neurobiology of Disease

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 313

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

The Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC), Horikoshi, M., Early Growth Genetics (EGG) Consortium, Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., Bradfield, J. P., St Pourcain, B., et al. (2013) · Nature Genetics

Birth, Development, and HealthGenetic Associations and Epidemiology

Cited by 309

Synergistic Effect of Histone Hyperacetylation and DNA Demethylation in the Reactivation of the FMR1 Gene

Chiurazzi, P., Grazia Pomponi, M., Pietrobono, R., Bakker, C. E., Neri, G., & Oostra, B. A. (1999) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation

Cited by 217

Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex

Kwan, K. Y., Lam, M. M. S., Johnson, M. B., Dube, U., Shim, S., Rašin, M.-R., Sousa, A. M. M., Fertuzinhos, S., Chen, J.-G., Arellano, J. I., et al. (2012) · Cell

Genetics and Neurodevelopmental DisordersRNA Research and Splicing

Cited by 137

Fragile X-related proteins regulate mammalian circadian behavioral rhythms

Zhang, J., Fang, Z., Jud, C., Vansteensel, M. J., Kaasik, K., Lee, C. C., Albrecht, U., Tamanini, F., Meijer, J. H., Oostra, B. A., et al. (2008) · The American Journal of Human Genetics

Circadian rhythm and melatoninGenetics and Neurodevelopmental Disorders

Cited by 131

Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice

Pilpel, Y., Kolleker, A., Berberich, S., Ginger, M., Frick, A., Mientjes, E., Oostra, B. A., & Seeburg, P. H. (2009) · The Journal of Physiology

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 102

Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice

Gantois, I., Pop, A. S., de Esch, C. E. F., Buijsen, R. A. M., Pooters, T., Gomez-Mancilla, B., Gasparini, F., Oostra, B. A., D’Hooge, R., & Willemsen, R. (2013) · Behavioural Brain Research

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 100

Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments

Tabolacci, E., Pietrobono, R., Moscato, U., Oostra, B. A., Chiurazzi, P., & Neri, G. (2005) · European Journal of Human Genetics

Genetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation

Cited by 92

Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes

Musumeci, S. A., Calabrese, G., Bonaccorso, C. M., D'Antoni, S., Brouwer, J. R., Bakker, C. E., Elia, M., Ferri, R., Nelson, D. L., Oostra, B. A., et al. (2007) · Experimental Neurology

Genetics and Neurodevelopmental DisordersEpilepsy research and treatment

Cited by 70

Analysis of LRRK2, SNCA, Parkin, PINK1, and DJ-1 in Zambian patients with Parkinson's disease

Yonova-Doing, E., Atadzhanov, M., Quadri, M., Kelly, P., Shawa, N., Musonda, S. T. S., Simons, E. J., Breedveld, G. J., Oostra, B. A., & Bonifati, V. (2012) · Parkinsonism & Related Disorders

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 56