Rubin, Edward M.

Community structure and metabolism through reconstruction of microbial genomes from the environment

Tyson, G. W., Chapman, J., Hugenholtz, P., Allen, E. E., Ram, R. J., Richardson, P. M., Solovyev, V. V., Rubin, E. M., Rokhsar, D. S., & Banfield, J. F. (2004) · Nature

Metal Extraction and BioleachingGenomics and Phylogenetic Studies

Cited by 2,417

Insights into the phylogeny and coding potential of microbial dark matter

Rinke, C., Schwientek, P., Sczyrba, A., Ivanova, N. N., Anderson, I. J., Cheng, J.-F., Darling, A., Malfatti, S., Swan, B. K., Gies, E. A., et al. (2013) · Nature

Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology

Cited by 2,394

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

Plump, A. S., Smith, J. D., Hayek, T., Aalto-Setälä, K., Walsh, A., Verstuyft, J. G., Rubin, E. M., & Breslow, J. L. (1992) · Cell

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 2,263

Metagenomic discovery of biomass-degrading genes and genomes from cow rumen

Hess, M., Sczyrba, A., Egan, R., Kim, T.-W., Chokhawala, H., Schroth, G., Luo, S., Clark, D. S., Chen, F., Zhang, T., et al. (2011) · Science

Biofuel production and bioconversionAnaerobic Digestion and Biogas Production

Cited by 1,319

In vivo enhancer analysis of human conserved non-coding sequences

Pennacchio, L. A., Ahituv, N., Moses, A. M., Prabhakar, S., Nobrega, M. A., Shoukry, M., Minovitsky, S., Dubchak, I., Holt, A., Lewis, K. D., et al. (2006) · Nature

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 1,165

An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing

Pennacchio, L. A., Olivier, M., Hubacek, J. A., Cohen, J. C., Cox, D. R., Fruchart, J.-C., Krauss, R. M., & Rubin, E. M. (2001) · Science

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 921

Improving the coverage of the cyanobacterial phylum using diversity driven genome sequencing

Shih, P. M., Wu, D., Latifi, A., Axen, S. D., Fewer, D. P., Talla, E., Calteau, A., Cai, F., Tandeau de Marsac, N., Rippka, R., et al. (2013) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesPhotosynthetic Processes and Mechanisms

Cited by 800

Sequencing and analysis of Neanderthal genomic DNA

Noonan, J. P., Coop, G., Kudaravalli, S., Smith, D., Krause, J., Alessi, J., Chen, F., Platt, D., Pääbo, S., Pritchard, J. K., et al. (2006) · Science

Pleistocene-Era Hominins and ArchaeologyGenomics and Phylogenetic Studies

Cited by 629

Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection

Hungate1000 project collaborators, Seshadri, R., Leahy, S. C., Attwood, G. T., Teh, K. H., Lambie, S. C., Cookson, A. L., Eloe-Fadrosh, E. A., Pavlopoulos, G. A., Hadjithomas, M., et al. (2018) · Nature Biotechnology

Ruminant Nutrition and Digestive PhysiologyAnaerobic Digestion and Biogas Production

Cited by 624

Genomic views of distant-acting enhancers

Visel, A., Rubin, E. M., & Pennacchio, L. A. (2009) · Nature

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 610

Scanning Human Gene Deserts for Long-Range Enhancers

Nobrega, M. A., Ovcharenko, I., Afzal, V., & Rubin, E. M. (2003) · Science

Genomics and Chromatin DynamicsCancer-related molecular mechanisms research

Cited by 608

Phylogenetic Shadowing of Primate Sequences to Find Functional Regions of the Human Genome

Boffelli, D., McAuliffe, J., Ovcharenko, D., Lewis, K. D., Ovcharenko, I., Pachter, L., & Rubin, E. M. (2003) · Science

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 516

Accelerated Evolution of Conserved Noncoding Sequences in Humans

Prabhakar, S., Noonan, J. P., Pääbo, S., & Rubin, E. M. (2006) · Science

Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies

Cited by 481

Transgenic Knockout Mice with Exclusively Human Sickle Hemoglobin and Sickle Cell Disease

Pászty, C., Brion, C. M., Manci, E., Witkowska, H. E., Stevens, M. E., Mohandas, N., & Rubin, E. M. (1997) · Science

Hemoglobinopathies and Related DisordersHemoglobin structure and function

Cited by 467

Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease

Loots, G. G., Kneissel, M., Keller, H., Baptist, M., Chang, J., Collette, N. M., Ovcharenko, D., Plajzer-Frick, I., & Rubin, E. M. (2005) · Genome Research

Bone Metabolism and DiseasesGenomics and Chromatin Dynamics

Cited by 442

Methane yield phenotypes linked to differential gene expression in the sheep rumen microbiome

Shi, W., Moon, C. D., Leahy, S. C., Kang, D., Froula, J., Kittelmann, S., Fan, C., Deutsch, S., Gagic, D., Seedorf, H., et al. (2014) · Genome Research

Ruminant Nutrition and Digestive PhysiologyAnaerobic Digestion and Biogas Production

Cited by 414

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

Sago, H., Carlson, E. J., Smith, D. J., Kilbridge, J., Rubin, E. M., Mobley, W. C., Epstein, C. J., & Huang, T.-T. (1998) · Proceedings of the National Academy of Sciences

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 382

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

Nord, A. S., Blow, M. J., Attanasio, C., Akiyama, J. A., Holt, A., Hosseini, R., Phouanenavong, S., Plajzer-Frick, I., Shoukry, M., Afzal, V., et al. (2013) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 375

Rumen metagenome and metatranscriptome analyses of low methane yield sheep reveals a Sharpea-enriched microbiome characterised by lactic acid formation and utilisation

Kamke, J., Kittelmann, S., Soni, P., Li, Y., Tavendale, M., Ganesh, S., Janssen, P. H., Shi, W., Froula, J., Rubin, E. M., et al. (2016) · Microbiome

Ruminant Nutrition and Digestive PhysiologyAnaerobic Digestion and Biogas Production

Cited by 339

Prehistoric genomes reveal the genetic foundation and cost of horse domestication

Schubert, M., Jónsson, H., Chang, D., Der Sarkissian, C., Ermini, L., Ginolhac, A., Albrechtsen, A., Dupanloup, I., Foucal, A., Petersen, B., et al. (2014) · Proceedings of the National Academy of Sciences

Genetic and phenotypic traits in livestockForensic and Genetic Research

Cited by 324

Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition

Mao, J. R., Taylor, G., Dean, W. B., Wagner, D. R., Afzal, V., Lotz, J. C., Rubin, E. M., & Bristow, J. (2002) · Nature Genetics

Connective tissue disorders researchSkin and Cellular Biology Research

Cited by 261

A High-Resolution Enhancer Atlas of the Developing Telencephalon

Visel, A., Taher, L., Girgis, H., May, D., Golonzhka, O., Hoch, R. V., McKinsey, G. L., Pattabiraman, K., Silberberg, S. N., Blow, M. J., et al. (2013) · Cell

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 257

Strategies and tools for whole-genome alignments

Couronne, O., Poliakov, A., Bray, N., Ishkhanov, T., Ryaboy, D., Rubin, E., Pachter, L., & Dubchak, I. (2003) · Genome Research

Genomics and Phylogenetic StudiesGenome Rearrangement Algorithms

Cited by 224

Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues

Huby, T., Doucet, C., Dachet, C., Ouzilleau, B., Ueda, Y., Afzal, V., Rubin, E., Chapman, M. J., & Lesnik, P. (2006) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 124