Sporn, Michael B.

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

Kulkarni, A. B., Huh, C. G., Becker, D., Geiser, A., Lyght, M., Flanders, K. C., Roberts, A. B., Sporn, M. B., Ward, J. M., & Karlsson, S. (1993) · Proceedings of the National Academy of Sciences

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NRF2 and cancer: the good, the bad and the importance of context

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Transforming Growth Factor‐β: Major Role in Regulation of Extracellular Matrix

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Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer

Liby, K. T., Yore, M. M., & Sporn, M. B. (2007) · Nature Reviews Cancer

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Localization and actions of transforming growth factor-β s in the embryonic nervous system

Flanders, K. C., Lüdecke, G., Engels, S., Cissel, D. S., Roberts, A. B., Kondaiah, P., Lafyatis, R., Sporn, M. B., & Unsicker, K. (1991) · Development

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Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

Sussan, T. E., Rangasamy, T., Blake, D. J., Malhotra, D., El-Haddad, H., Bedja, D., Yates, M. S., Kombairaju, P., Yamamoto, M., Liby, K. T., et al. (2009) · Proceedings of the National Academy of Sciences

Chronic Obstructive Pulmonary Disease (COPD) ResearchGenomics, phytochemicals, and oxidative stress

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The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling

Liby, K., Hock, T., Yore, M. M., Suh, N., Place, A. E., Risingsong, R., Williams, C. R., Royce, D. B., Honda, T., Honda, Y., et al. (2005) · Cancer Research

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Synthetic oleanane and ursane triterpenoids with modified rings A and C: a series of highly active inhibitors of nitric oxide production in mouse macrophages

Honda, T., Rounds, B. V., Bore, L., Finlay, H. J., Favaloro, Suh, N., Wang, Y., Sporn, M. B., & Gribble, G. W. (2000) · Journal of Medicinal Chemistry

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Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype.

Geiser, A. G., Letterio, J. J., Kulkarni, A. B., Karlsson, S., Roberts, A. B., & Sporn, M. B. (1993) · Proceedings of the National Academy of Sciences

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The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism

Ito, Y., Pandey, P., Sporn, M. B., Datta, R., Kharbanda, S., & Kufe, D. (2001) · Molecular Pharmacology

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