Lindquist, Susan

Under cover: causes, effects and implications of Hsp90‐mediated genetic capacitance

Sangster, T. A., Lindquist, S., & Queitsch, C. (2004) · BioEssays

Heat shock proteins researchEvolution and Genetic Dynamics

Cited by 251

Protein Homeostasis and the Phenotypic Manifestation of Genetic Diversity: Principles and Mechanisms

Jarosz, D. F., Taipale, M., & Lindquist, S. (2010) · Annual Review of Genetics

Evolution and Genetic DynamicsHeat shock proteins research

Cited by 179

HSP90 affects the expression of genetic variation and developmental stability in quantitative traits

Sangster, T. A., Salathia, N., Undurraga, S., Milo, R., Schellenberg, K., Lindquist, S., & Queitsch, C. (2008) · Proceedings of the National Academy of Sciences

Heat shock proteins researchEvolution and Genetic Dynamics

Cited by 174

Genetic Architecture of Hsp90-Dependent Drug Resistance

Cowen, L. E., Carpenter, A. E., Matangkasombut, O., Fink, G. R., & Lindquist, S. (2006) · Eukaryotic Cell

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 159

HSP90-buffered genetic variation is common in Arabidopsis thaliana

Sangster, T. A., Salathia, N., Lee, H. N., Watanabe, E., Schellenberg, K., Morneau, K., Wang, H., Undurraga, S., Queitsch, C., & Lindquist, S. (2008) · Proceedings of the National Academy of Sciences

Heat shock proteins researchEvolution and Genetic Dynamics

Cited by 131

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus

Whitesell, L., Robbins, N., Huang, D. S., McLellan, C. A., Shekhar-Guturja, T., LeBlanc, E. V., Nation, C. S., Hui, R., Hutchinson, A., Collins, C., et al. (2019) · Nature Communications

Heat shock proteins researchAntifungal resistance and susceptibility

Cited by 124

Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity

McLellan, C. A., Whitesell, L., King, O. D., Lancaster, A. K., Mazitschek, R., & Lindquist, S. (2012) · ACS Chemical Biology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 115

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

Tsvetkov, P., Mendillo, M. L., Zhao, J., Carette, J. E., Merrill, P. H., Cikes, D., Varadarajan, M., van Diemen, F. R., Penninger, J. M., Goldberg, A. L., et al. (2015) · eLife

Ubiquitin and proteasome pathwaysHeat shock proteins research

Cited by 83

PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4

Narayan, P., Sienski, G., Bonner, J. M., Lin, Y.-T., Seo, J., Baru, V., Haque, A., Milo, B., Akay, L. A., Graziosi, A., et al. (2020) · Cell Reports

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 75

A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance

Vincent, B. M., Langlois, J.-B., Srinivas, R., Lancaster, A. K., Scherz-Shouval, R., Whitesell, L., Tidor, B., Buchwald, S. L., & Lindquist, S. (2016) · Cell Chemical Biology

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 58

Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy

McLellan, C. A., Vincent, B. M., Solis, N. V., Lancaster, A. K., Sullivan, L. B., Hartland, C. L., Youngsaye, W., Filler, S. G., Whitesell, L., & Lindquist, S. (2018) · Nature Chemical Biology

Antifungal resistance and susceptibilityMitochondrial Function and Pathology

Cited by 49