Pombo, Joaquim

Cardiac glycosides are broad-spectrum senolytics

Guerrero, A., Herranz, N., Sun, B., Wagner, V., Gallage, S., Guiho, R., Wolter, K., Pombo, J., Irvine, E. E., Innes, A. J., et al. (2019) · Nature Metabolism

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 359

PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells

Georgilis, A., Klotz, S., Hanley, C. J., Herranz, N., Weirich, B., Morancho, B., Leote, A. C., D'Artista, L., Gallage, S., Seehawer, M., et al. (2018) · Cancer Cell

Telomeres, Telomerase, and SenescenceRNA Research and Splicing

Cited by 237

Maternal obesity programs offspring nonalcoholic fatty liver disease by innate immune dysfunction in mice

Mouralidarane, A., Soeda, J., Visconti-Pugmire, C., Samuelsson, A.-M., Pombo, J., Maragkoudaki, X., Butt, A., Saraswati, R., Novelli, M., Fusai, G., et al. (2013) · Hepatology

Liver Disease Diagnosis and TreatmentBirth, Development, and Health

Cited by 145

Evidence for sympathetic origins of hypertension in juvenile offspring of obese rats

Samuelsson, A.-M., Morris, A., Igosheva, N., Kirk, S. L., Pombo, J. M. C., Coen, C. W., Poston, L., & Taylor, P. D. (2010) · Hypertension

Birth, Development, and HealthBlood Pressure and Hypertension Studies

Cited by 138

Detection of senescence using machine learning algorithms based on nuclear features

Duran, I., Pombo, J., Sun, B., Gallage, S., Kudo, H., McHugh, D., Bousset, L., Barragan Avila, J. E., Forlano, R., Manousou, P., et al. (2024) · Nature Communications

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 85

Ribosomal S6 kinase 1 regulates ‘inflammaging’ via the senescence secretome

Gallage, S., Irvine, E. E., Pedroni, S. M. A., Barragan Avila, J. E., Khadayate, S., Pombo, J., Brookes, S., Heide, D., Dharmalingham, G., Choudhury, A. I., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 31

XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence

Innes, A. J., Sun, B., Wagner, V., Brookes, S., McHugh, D., Pombo, J., Porreca, R. M., Dharmalingam, G., Vernia, S., Zuber, J., et al. (2021) · Genes & Development

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 30