Smyth, Deborah J.

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

Ueda, H., Howson, J. M. M., Esposito, L., Heward, J., Snook, Chamberlain, G., Rainbow, D. B., Hunter, K. M. D., Smith, A. N., Di Genova, G., et al. (2003) · Nature

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 2,175

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

The Type 1 Diabetes Genetics Consortium, Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., et al. (2009) · Nature Genetics

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 1,746

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Finland, G. O. T. 1. D. I., Todd, J. A., the Wellcome Trust Case Control Consortium, Walker, N. M., Cooper, J. D., Smyth, D. J., Downes, K., Plagnol, V., Bailey, R., Nejentsev, S., et al. (2007) · Nature Genetics

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 1,456

Population structure, differential bias and genomic control in a large-scale, case-control association study

Clayton, D. G., Walker, N. M., Smyth, D. J., Pask, R., Cooper, J. D., Maier, L. M., Smink, L. J., Lam, A. C., Ovington, N. R., Stevens, H. E., et al. (2005) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 526

Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

Ferreira, R. C., Freitag, D. F., Cutler, A. J., Howson, J. M. M., Rainbow, D. B., Smyth, D. J., Kaptoge, S., Clarke, P., Boreham, C., Coulson, R. M., et al. (2013) · PLoS Genetics

Cytokine Signaling Pathways and InteractionsGenetic Associations and Epidemiology

Cited by 316

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

Cardiogenics Consortium, Heinig, M., Petretto, E., Wallace, C., Bottolo, L., Rotival, M., Lu, H., Li, Y., Sarwar, R., Langley, S. R., et al. (2010) · Nature

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 283

Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

Cooper, J. D., Smyth, D. J., Walker, N. M., Stevens, H., Burren, O. S., Wallace, C., Greissl, C., Ramos-Lopez, E., Hyppönen, E., Dunger, D. B., et al. (2011) · Diabetes

Vitamin D Research StudiesDiabetes and associated disorders

Cited by 279

Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

Cano-Gamez, K., Soskic, B., Roumeliotis, T. I., So, E., Smyth, D. J., Baldrighi, M., Willé, D., Nakic, N., Esparza-Gordillo, J., Larminie, C. G. C., et al. (2020) · Nature Communications

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 274

Genetic Analysis of Adult-Onset Autoimmune Diabetes

Howson, J. M. M., Rosinger, S., Smyth, D. J., Boehm, B. O., the ADBW-END Study Group, & Todd, J. A. (2011) · Diabetes

Diabetes and associated disordersGenetic Associations and Epidemiology

Cited by 143

Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13

Plagnol, V., Smyth, D. J., Todd, J. A., & Clayton, D. G. (2009) · Biostatistics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 113

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing

Rainbow, D. B., Yang, X., Burren, O., Pekalski, M. L., Smyth, D. J., Klarqvist, M. D. R., Penkett, C. J., Brugger, K., Martin, H., Todd, J. A., et al. (2015) · European Journal of Immunology

T-cell and B-cell ImmunologyEpigenetics and DNA Methylation

Cited by 26