Korsmeyer, Stanley J.

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Oltval, Z. N., Milliman, C. L., & Korsmeyer, S. J. (1993) · Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 6,003

Cell Death

Danial, N. N., & Korsmeyer, S. J. (2004) · Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 4,651

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Wei, M. C., Zong, W.-X., Cheng, E. H.-Y., Lindsten, T., Panoutsakopoulou, V., Ross, A. J., Roth, K. A., MacGregor, G. R., Thompson, C. B., & Korsmeyer, S. J. (2001) · Science

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 3,988

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

Hockenbery, D., Nuñez, G., Milliman, C., Schreiber, R. D., & Korsmeyer, S. J. (1990) · Nature

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 3,720

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

Letai, A., Bassik, M. C., Walensky, L. D., Sorcinelli, M. D., Weiler, S., & Korsmeyer, S. J. (2002) · Cancer Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 1,677

The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues

Lindsten, T., Ross, A. J., King, A., Zong, W.-X., Rathmell, J. C., Shiels, H. A., Ulrich, E., Waymire, K. G., Mahar, P., Frauwirth, K., et al. (2000) · Molecular Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 1,489

Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix

Walensky, L. D., Kung, A. L., Escher, I., Malia, T. J., Barbuto, S., Wright, R. D., Wagner, G., Verdine, G. L., & Korsmeyer, S. J. (2004) · Science

Cell death mechanisms and regulationChemical Synthesis and Analysis

Cited by 1,349

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

Hockenbery, D. M., Zutter, M., Hickey, W., Nahm, M., & Korsmeyer, S. J. (1991) · Proceedings of the National Academy of Sciences

Cell death mechanisms and regulationT-cell and B-cell Immunology

Cited by 1,252

bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

McDonnell, T. J., Deane, N., Platt, F. M., Nunez, G., Jaeger, U., McKearn, J. P., & Korsmeyer, S. J. (1989) · Cell

Lymphoma Diagnosis and TreatmentViral-associated cancers and disorders

Cited by 1,213

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

He, C., Bassik, M. C., Moresi, V., Sun, K., Wei, Y., Zou, Z., An, Z., Loh, J., Fisher, J., Sun, Q., et al. (2012) · Nature

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 1,136

A Distinct Pathway Remodels Mitochondrial Cristae and Mobilizes Cytochrome c during Apoptosis

Scorrano, L., Ashiya, M., Buttle, K., Weiler, S., Oakes, S. A., Mannella, C. A., & Korsmeyer, S. J. (2002) · Developmental Cell

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 1,072

Caspase Cleaved BID Targets Mitochondria and Is Required for Cytochrome c Release, while BCL-XL Prevents This Release but Not Tumor Necrosis Factor-R1/Fas Death

Gross, A., Yin, X.-M., Wang, K., Wei, M. C., Jockel, J., Milliman, C., Erdjument-Bromage, H., Tempst, P., & Korsmeyer, S. J. (1999) · Journal of Biological Chemistry

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 1,045

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

Yin, X.-M., Wang, K., Gross, A., Zhao, Y., Zinkel, S., Klocke, B., Roth, K. A., & Korsmeyer, S. J. (1999) · Nature

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 1,004

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

Nuñez, G., London, L., Hockenbery, D., Alexander, M., McKearn, J. P., & Korsmeyer, S. J. (1990) · The Journal of Immunology

Cell death mechanisms and regulationLymphoma Diagnosis and Treatment

Cited by 899

VDAC2 Inhibits BAK Activation and Mitochondrial Apoptosis

Cheng, E. H.-Y., Sheiko, T. V., Fisher, J. K., Craigen, W. J., & Korsmeyer, S. J. (2003) · Science

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 852

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

Schinzel, A. C., Takeuchi, O., Huang, Z., Fisher, J. K., Zhou, Z., Rubens, J., Hetz, C., Danial, N. N., Moskowitz, M. A., & Korsmeyer, S. J. (2005) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 820

BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

Danial, N. N., Gramm, C. F., Scorrano, L., Zhang, C.-Y., Krauss, S., Ranger, A. M., Robert Datta, S., Greenberg, M. E., Licklider, L. J., Lowell, B. B., et al. (2003) · Nature

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 705

BID regulation by p53 contributes to chemosensitivity

Sax, J. K., Fei, P., Murphy, M. E., Bernhard, E., Korsmeyer, S. J., & El-Deiry, W. S. (2002) · Nature Cell Biology

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 420

Mcl-1 deficiency results in peri-implantation embryonic lethality

Rinkenberger, J. L., Horning, S., Klocke, B., Roth, K., & Korsmeyer, S. J. (2000) · Genes & Development

Developmental Biology and Gene RegulationReproductive Biology and Fertility

Cited by 397

A Stapled BID BH3 Helix Directly Binds and Activates BAX

Walensky, L. D., Pitter, K., Morash, J., Oh, K. J., Barbuto, S., Fisher, J., Smith, E., Verdine, G. L., & Korsmeyer, S. J. (2006) · Molecular Cell

Cell death mechanisms and regulationChemical Synthesis and Analysis

Cited by 383

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

Danial, N. N., Walensky, L. D., Zhang, C.-Y., Choi, C. S., Fisher, J. K., Molina, A. J. A., Datta, S. R., Pitter, K. L., Bird, G. H., Wikstrom, J. D., et al. (2008) · Nature Medicine

Pancreatic function and diabetesCell death mechanisms and regulation

Cited by 307

A Role for Proapoptotic BID in the DNA-Damage Response

Zinkel, S. S., Hurov, K. E., Ong, C., Abtahi, F. M., Gross, A., & Korsmeyer, S. J. (2005) · Cell

Cell death mechanisms and regulationDNA Repair Mechanisms

Cited by 239

Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia

Hetz, C., Vitte, P.-A., Bombrun, A., Rostovtseva, T. K., Montessuit, S., Hiver, A., Schwarz, M. K., Church, D. J., Korsmeyer, S. J., Martinou, J.-C., et al. (2005) · Journal of Biological Chemistry

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 176