Hamilton, Geraldine A.

From 3D cell culture to organs-on-chips

Huh, D., Hamilton, G. A., & Ingber, D. E. (2011) · Trends in Cell Biology

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 1,834

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

Kim, H. J., Huh, D., Hamilton, G., & Ingber, D. E. (2012) · Lab on a Chip

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 1,734

A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice

Huh, D., Leslie, D. C., Matthews, B. D., Fraser, J. P., Jurek, S., Hamilton, G. A., Thorneloe, K. S., McAlexander, M. A., & Ingber, D. E. (2012) · Science Translational Medicine

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 993

Microfabrication of human organs-on-chips

Huh, D., Kim, H. J., Fraser, J. P., Shea, D. E., Khan, M., Bahinski, A., Hamilton, G. A., & Ingber, D. E. (2013) · Nature Protocols

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 712

Reproducing human and cross-species drug toxicities using a liver-chip

Jang, K.-J., Otieno, M. A., Ronxhi, J., Lim, H.-K., Ewart, L., Kodella, K. R., Petropolis, D. B., Kulkarni, G., Rubins, J. E., Conegliano, D., et al. (2019) · Science Translational Medicine

Drug-Induced Hepatotoxicity and Protection3D Printing in Biomedical Research

Cited by 511

Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems

Odijk, M., van der Meer, A. D., Levner, D., Kim, H. J., van der Helm, M. W., Segerink, L. I., Frimat, J.-P., Hamilton, G. A., Ingber, D. E., & van den Berg, A. (2015) · Lab on a Chip

3D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis Applications

Cited by 209

Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium

Jain, A., van der Meer, A. D., Papa, A.-L., Barrile, R., Lai, A., Schlechter, B. L., Otieno, M. A., Louden, C. S., Hamilton, G. A., Michelson, A. D., et al. (2016) · Biomedical Microdevices

Platelet Disorders and TreatmentsBlood properties and coagulation

Cited by 148

Organ‐on‐Chip recapitulates thrombosis induced by an anti‐CD154 monoclonal antibody: translational potential of advanced microengineered systems

Barrile, R., van der Meer, A. D., Park, H., Fraser, J. P., Simic, D., Teng, F., Conegliano, D., Nguyen, J., Jain, A., Zhou, M., et al. (2018) · Clinical Pharmacology & Therapeutics

3D Printing in Biomedical ResearchBlood Coagulation and Thrombosis Mechanisms

Cited by 138

Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid

Foster, A. J., Chouhan, B., Regan, S. L., Rollison, H., Amberntsson, S., Andersson, L. C., Srivastava, A., Darnell, M., Cairns, J., Lazic, S. E., et al. (2019) · Archives of Toxicology

Drug-Induced Hepatotoxicity and Protection3D Printing in Biomedical Research

Cited by 117

Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition

Sahi, J., Black, C. B., Hamilton, G. A., Zheng, X., Jolley, S., Rose, K. A., Gilbert, D., LeCluyse, E. L., & Sinz, M. W. (2003) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 113

Modeling alcohol-associated liver disease in a human Liver-Chip

Nawroth, J. C., Petropolis, D. B., Manatakis, D. V., Maulana, T. I., Burchett, G., Schlünder, K., Witt, A., Shukla, A., Kodella, K., Ronxhi, J., et al. (2021) · Cell Reports

Alcohol Consumption and Health Effects3D Printing in Biomedical Research

Cited by 88

Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

Kerns, S. J., Belgur, C., Petropolis, D., Kanellias, M., Barrile, R., Sam, J., Weinzierl, T., Fauti, T., Freimoser-Grundschober, A., Eckmann, J., et al. (2021) · eLife

3D Printing in Biomedical ResearchImmunotoxicology and immune responses

Cited by 82