Boyden, Edward S.

Independent optical excitation of distinct neural populations

Klapoetke, N. C., Murata, Y., Kim, S. S., Pulver, S. R., Birdsey-Benson, A., Cho, Y. K., Morimoto, T. K., Chuong, A. S., Carpenter, E. J., Tian, Z., et al. (2014) · Nature Methods

Photoreceptor and optogenetics researchNeurobiology and Insect Physiology Research

Cited by 2,344

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

Madisen, L., Mao, T., Koch, H., Zhuo, J.-M., Berenyi, A., Fujisawa, S., Hsu, Y.-W. A., Garcia, A. J., Gu, X., Zanella, S., et al. (2012) · Nature Neuroscience

Photoreceptor and optogenetics researchNeuroscience and Neuropharmacology Research

Cited by 1,398

Gamma frequency entrainment attenuates amyloid load and modifies microglia

Iaccarino, H. F., Singer, A. C., Martorell, A. J., Rudenko, A., Gao, F., Gillingham, T. Z., Mathys, H., Seo, J., Kritskiy, O., Abdurrob, F., et al. (2016) · Nature

Alzheimer's disease research and treatmentsNeural dynamics and brain function

Cited by 1,328

Cell diversity and network dynamics in photosensitive human brain organoids

Quadrato, G., Nguyen, T., Macosko, E. Z., Sherwood, J. L., Min Yang, S., Berger, D. R., Maria, N., Scholvin, J., Goldman, M., Kinney, J. P., et al. (2017) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 1,321

Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance

Madisen, L., Garner, A. R., Shimaoka, D., Chuong, A. S., Klapoetke, N. C., Li, L., van der Bourg, A., Niino, Y., Egolf, L., Monetti, C., et al. (2015) · Neuron

Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research

Cited by 1,114

A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality

Daigle, T. L., Madisen, L., Hage, T. A., Valley, M. T., Knoblich, U., Larsen, R. S., Takeno, M. M., Huang, L., Gu, H., Larsen, R., et al. (2018) · Cell

Neuroscience and Neuropharmacology ResearchAnimal Genetics and Reproduction

Cited by 817

Multi-sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition

Martorell, A. J., Paulson, A. L., Suk, H.-J., Abdurrob, F., Drummond, G. T., Guan, W., Young, J. Z., Kim, D. N.-W., Kritskiy, O., Barker, S. J., et al. (2019) · Cell

Alzheimer's disease research and treatmentsNeural dynamics and brain function

Cited by 798

Activation of specific interneurons improves V1 feature selectivity and visual perception

Lee, S.-H., Kwan, A. C., Zhang, S., Phoumthipphavong, V., Flannery, J. G., Masmanidis, S. C., Taniguchi, H., Huang, Z. J., Zhang, F., Boyden, E. S., et al. (2012) · Nature

Visual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Cited by 593

A jump-start for electroceuticals

Famm, K., Litt, B., Tracey, K. J., Boyden, E. S., & Slaoui, M. (2013) · Nature

Neuroscience and Neural EngineeringVagus Nerve Stimulation Research

Cited by 554

Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER

Saka, S. K., Wang, Y., Kishi, J. Y., Zhu, A., Zeng, Y., Xie, W., Kirli, K., Yapp, C., Cicconet, M., Beliveau, B. J., et al. (2018) · Nature Biotechnology

Advanced biosensing and bioanalysis techniquesAdvanced Fluorescence Microscopy Techniques

Cited by 485

Cerebellum-dependent learning: the role of multiple plasticity mechanisms

Boyden, E. S., Katoh, A., & Raymond, J. L. (2004) · Annual Review of Neuroscience

Motor Control and AdaptationMemory and Neural Mechanisms

Cited by 448

Autism genes converge on asynchronous development of shared neuron classes

Paulsen, B., Velasco, S., Kedaigle, A. J., Pigoni, M., Quadrato, G., Deo, A. J., Adiconis, X., Uzquiano, A., Sartore, R., Yang, S. M., et al. (2022) · Nature

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 439

Multisensory gamma stimulation promotes glymphatic clearance of amyloid

Murdock, M. H., Yang, C.-Y., Sun, N., Pao, P.-C., Blanco-Duque, C., Kahn, M. C., Kim, T., Lavoie, N. S., Victor, M. B., Islam, M. R., et al. (2024) · Nature

Cerebrospinal fluid and hydrocephalusAlzheimer's disease research and treatments

Cited by 379

Oxytocin-dependent reopening of a social reward learning critical period with MDMA

Nardou, R., Lewis, E. M., Rothhaas, R., Xu, R., Yang, A., Boyden, E., & Dölen, G. (2019) · Nature

Neuroendocrine regulation and behaviorNeuroscience and Neuropharmacology Research

Cited by 334

Glyoxal as an alternative fixative to formaldehyde in immunostaining and super‐resolution microscopy

Richter, K. N., Revelo, N. H., Seitz, K. J., Helm, M. S., Sarkar, D., Saleeb, R. S., D'Este, E., Eberle, J., Wagner, E., Vogl, C., et al. (2018) · The EMBO Journal

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

Cited by 314

Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia

Taylor, N. E., Van Dort, C. J., Kenny, J. D., Pei, J., Guidera, J. A., Vlasov, K. Y., Lee, J. T., Boyden, E. S., Brown, E. N., & Solt, K. (2016) · Proceedings of the National Academy of Sciences

Sleep and Wakefulness ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 269

Optogenetic inactivation modifies monkey visuomotor behavior

Cavanaugh, J., Monosov, I. E., McAlonan, K., Berman, R., Smith, M. K., Cao, V., Wang, K. H., Boyden, E. S., & Wurtz, R. H. (2012) · Neuron

Photoreceptor and optogenetics researchVisual perception and processing mechanisms

Cited by 124

One-step nanoscale expansion microscopy reveals individual protein shapes

Shaib, A. H., Chouaib, A. A., Chowdhury, R., Altendorf, J., Mihaylov, D., Zhang, C., Krah, D., Imani, V., Spencer, R. K. W., Georgiev, S. V., et al. (2025) · Nature Biotechnology

Advanced Fluorescence Microscopy TechniquesForce Microscopy Techniques and Applications

Cited by 104

A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve

Caravaca, A. S., Tsaava, T., Goldman, L., Silverman, H., Riggott, G., Chavan, S. S., Bouton, C., Tracey, K. J., Desimone, R., Boyden, E. S., et al. (2017) · Journal of Neural Engineering

Neuroscience and Neural EngineeringVagus Nerve Stimulation Research

Cited by 57

Proceedings of the sixth deep brain stimulation think tank modulation of brain networks and application of advanced neuroimaging, neurophysiology, and optogenetics

Ramirez-Zamora, A., Giordano, J., Boyden, E. S., Gradinaru, V., Gunduz, A., Starr, P. A., Sheth, S. A., McIntyre, C. C., Fox, M. D., Vitek, J., et al. (2019) · Frontiers in Neuroscience

Deep Brain Stimulation and Movement DisordersObsessive-Compulsive Spectrum Disorders

Cited by 37

Noninvasive optical inhibition with a red-shifted microbial rhodopsin

Chuong, A. S., Miri, M. L., Busskamp, V., Matthews, G. A. C., Acker, L. C., Sørensen, A. T., Young, A., Klapoetke, N. C., Henninger, M. A., Kodandaramaiah, S. B., et al. (2014) · Nature Neuroscience

Photoreceptor and optogenetics researchNeuroscience and Neural Engineering

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