Bok, Dean

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle

Redmond., T. M., Yu, S., Lee, E., Bok, D., Hamasaki, D., Chen, N., Goletz, P., Ma, J.-X., Crouch, R. K., & Pfeifer, K. (1998) · Nature Genetics

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 929

A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A

Kawaguchi, R., Yu, J., Honda, J., Hu, J., Whitelegge, J., Ping, P., Wiita, P., Bok, D., & Sun, H. (2007) · Science

Retinoids in leukemia and cellular processesRetinal Development and Disorders

Cited by 836

The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited

Anderson, D. H., Radeke, M. J., Gallo, N. B., Chapin, E. A., Johnson, P. T., Curletti, C. R., Hancox, L. S., Hu, J., Ebright, J. N., Malek, G., et al. (2010) · Progress in Retinal and Eye Research

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 727

The retinal pigment epithelium: a versatile partner in vision

Bok, D. (1993) · Journal of Cell Science

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 593

mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice

Zhao, C., Yasumura, D., Li, X., Matthes, M., Lloyd, M., Nielsen, G., Ahern, K., Snyder, M., Bok, D., Dunaief, J. L., et al. (2011) · Journal of Clinical Investigation

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 303

Molecular and Biochemical Characterization of Lecithin Retinol Acyltransferase

Ruiz, A., Winston, A., Lim, Y.-H., Gilbert, B. A., Rando, R. R., & Bok, D. (1999) · Journal of Biological Chemistry

Retinoids in leukemia and cellular processesCholesterol and Lipid Metabolism

Cited by 265

Accelerated Accumulation of Lipofuscin Pigments in the RPE of a Mouse Model for ABCA4-Mediated Retinal Dystrophies following Vitamin A Supplementation

Radu, R. A., Yuan, Q., Hu, J., Peng, J. H., Lloyd, M., Nusinowitz, S., Bok, D., & Travis, G. H. (2008) · Investigative Opthalmology & Visual Science

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 188

Neurotrophins enhance retinal pigment epithelial cell survival through neuroprotectin D1 signaling

Mukherjee, P. K., Marcheselli, V. L., Barreiro, S., Hu, J., Bok, D., & Bazan, N. G. (2007) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 170

Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration

Lenis, T. L., Hu, J., Ng, S. Y., Jiang, Z., Sarfare, S., Lloyd, M. B., Esposito, N. J., Samuel, W., Jaworski, C., Bok, D., et al. (2018) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 158

Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for stargardt macular degeneration

Radu, R. A., Hu, J., Yuan, Q., Welch, D. L., Makshanoff, J., Lloyd, M., McMullen, S., Travis, G. H., & Bok, D. (2011) · Journal of Biological Chemistry

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 157

Phagocytosis of outer segments by retinal pigment epithelium: phagosome-lysosome interaction

Bosch, E., Horwitz, J., & Bok, D. (1993) · Journal of Histochemistry & Cytochemistry

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 147

The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptors

Jin, M., Li, S., Nusinowitz, S., Lloyd, M., Hu, J., Radu, R. A., Bok, D., & Travis, G. H. (2009) · The Journal of Neuroscience

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 109

Retinoid Content, Visual Responses, and Ocular Morphology Are Compromised in the Retinas of Mice Lacking the Retinol-Binding Protein Receptor, STRA6

Ruiz, A., Mark, M., Jacobs, H., Klopfenstein, M., Hu, J., Lloyd, M., Habib, S., Tosha, C., Radu, R. A., Ghyselinck, N. B., et al. (2012) · Investigative Opthalmology & Visual Science

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 105

CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Müller glial cells

Rhee, K. D., Nusinowitz, S., Chao, K., Yu, F., Bok, D., & Yang, X.-J. (2013) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 92

Retinal Pigment Epithelium-Retinal G Protein Receptor-Opsin Mediates Light-dependent Translocation of All-trans-retinyl Esters for Synthesis of Visual Chromophore in Retinal Pigment Epithelial Cells

Radu, R. A., Hu, J., Peng, J., Bok, D., Mata, N. L., & Travis, G. H. (2008) · Journal of Biological Chemistry

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 83

Purification and Characterization of a Transmembrane Domain-Deleted Form of Lecithin Retinol Acyltransferase

Bok, D., Ruiz, A., Yaron, O., Jahng, W. J., Ray, A., Xue, L., & Rando, R. R. (2003) · Biochemistry

Retinoids in leukemia and cellular processesPhotoreceptor and optogenetics research

Cited by 47

Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype

Radu, R. A., Hu, J., Jiang, Z., & Bok, D. (2014) · Journal of Biological Chemistry

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 44

Claudin localization in cilia of the retinal pigment epithelium

Nishiyama, K., Sakaguchi, H., Hu, J. G., Bok, D., & Hollyfield, J. G. (2002) · The Anatomical Record

Genetic and Kidney Cyst DiseasesRetinal Development and Disorders

Cited by 33

Culture of Highly Differentiated Human Retinal Pigment Epithelium for Analysis of the Polarized Uptake, Processing, and Secretion of Retinoids

Hu, J., & Bok, D. (2010) · Methods in Molecular Biology

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 24