Bredesen, Dale E.
Buck Institute for Research on Aging · University of California, Los Angeles
13 papers on CoChatORCID 0009-0000-1984-5220
Most cited papers
- Verified
Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease
Spilman, P., Podlutskaya, N., Hart, M. J., Debnath, J., Gorostiza, O., Bredesen, D., Richardson, A., Strong, R., & Galvan, V. (2010) · PLoS ONE
Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy
Cited by 1,033
- Verified
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., et al. (2015) · Cell Death & Differentiation
Cell death mechanisms and regulationAutophagy in Disease and Therapy
Cited by 1,002
- Verified
Reversal of Alzheimer’s-like pathology and behavior in human APP transgenic mice by mutation of Asp664
Galvan, V., Gorostiza, O. F., Banwait, S., Ataie, M., Logvinova, A. V., Sitaraman, S., Carlson, E., Sagi, S. A., Chevallier, N., Jin, K., et al. (2006) · Proceedings of the National Academy of Sciences
Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms
Cited by 239
- Verified
Ayurvedic medicinal plants for Alzheimer’s disease: A review
Rao, R. V., Descamps, O., John, V., & Bredesen, D. E. (2012) · Alzheimer's Research & Therapy
Medicinal Plants and NeuroprotectionAlzheimer's disease research and treatments
Cited by 213
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Focal degeneration of astrocytes in amyotrophic lateral sclerosis
Rossi, D., Brambilla, L., Valori, C. F., Roncoroni, C., Crugnola, A., Yokota, T., Bredesen, D. E., & Volterra, A. (2008) · Cell Death & Differentiation
Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments
Cited by 194
- Verified
Direct Transcriptional Effects of Apolipoprotein E
Theendakara, V., Peters-Libeu, C. A., Spilman, P., Poksay, K. S., Bredesen, D. E., & Rao, R. V. (2016) · The Journal of Neuroscience
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 152
- Verified
Many Neuronal and Behavioral Impairments in Transgenic Mouse Models of Alzheimer's Disease Are Independent of Caspase Cleavage of the Amyloid Precursor Protein
Harris, J. A., Devidze, N., Halabisky, B., Lo, I., Thwin, M. T., Yu, G.-Q., Bredesen, D. E., Masliah, E., & Mucke, L. (2010) · The Journal of Neuroscience
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 146
- Verified
Neuroprotective Sirtuin ratio reversed by ApoE4
Theendakara, V., Patent, A., Peters Libeu, C. A., Philpot, B., Flores, S., Descamps, O., Poksay, K. S., Zhang, Q., Cailing, G., Hart, M., et al. (2013) · Proceedings of the National Academy of Sciences
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 101
- Verified
Metabolic profiling distinguishes three subtypes of Alzheimer's disease
Bredesen, D. E. (2015) · Aging
Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments
Cited by 76
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Science fact and the SENS agenda: What can we reasonably expect from ageing research?
Warner, H., Anderson, J., Austad, S., Bergamini, E., Bredesen, D., Butler, R., Carnes, B. A., Clark, B. F. C., Cristofalo, V., Faulkner, J., et al. (2005) · The EMBO Reports
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 74
- Verified
Dependence Receptors: From Basic Research to Drug Development
Mehlen, P., & Bredesen, D. E. (2011) · Science Signaling
Nerve injury and regenerationCell death mechanisms and regulation
Cited by 72
- Verified
Transcriptional Effects of ApoE4: Relevance to Alzheimer’s Disease
Theendakara, V., Peters-Libeu, C. A., Bredesen, D. E., & Rao, R. V. (2018) · Molecular Neurobiology
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 63
- Verified
Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer’s Disease
Spilman, P. R., Corset, V., Gorostiza, O., Poksay, K. S., Galvan, V., Zhang, J., Rao, R., Peters-Libeu, C., Vincelette, J., McGeehan, A., et al. (2016) · Journal of Alzheimer's Disease
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research
Cited by 39
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