Hakkarainen, Antti

Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars

Luukkonen, P. K., Sädevirta, S., Zhou, Y., Kayser, B., Ali, A., Ahonen, L., Lallukka, S., Pelloux, V., Gaggini, M., Jian, C., et al. (2018) · Diabetes Care

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 428

Impaired Mitochondrial Biogenesis in Adipose Tissue in Acquired Obesity

Heinonen, S., Buzkova, J., Muniandy, M., Kaksonen, R., Ollikainen, M., Ismail, K., Hakkarainen, A., Lundbom, J., Lundbom, N., Vuolteenaho, K., et al. (2015) · Diabetes

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 362

Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans

Sevastianova, K., Santos, A., Kotronen, A., Hakkarainen, A., Makkonen, J., Silander, K., Peltonen, M., Romeo, S., Lundbom, J., Lundbom, N., et al. (2012) · The American Journal of Clinical Nutrition

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 211

Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects

Kotronen, A., Juurinen, L., Hakkarainen, A., Westerbacka, J., Cornér, A., Bergholm, R., & Yki-Järvinen, H. (2008) · Diabetes Care

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 196

Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease

Luukkonen, P. K., Qadri, S., Ahlholm, N., Porthan, K., Männistö, V., Sammalkorpi, H., Penttilä, A. K., Hakkarainen, A., Lehtimäki, T. E., Gaggini, M., et al. (2022) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 170

Dual metabolic defects are required to produce hypertriglyceridemia in obese subjects

Taskinen, M.-R., Adiels, M., Westerbacka, J., Söderlund, S., Kahri, J., Lundbom, N., Lundbom, J., Hakkarainen, A., Olofsson, S.-O., Orho-Melander, M., et al. (2011) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipid metabolism and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 153

Effects of insulin therapy on liver fat content and hepatic insulin sensitivity in patients with type 2 diabetes

Juurinen, L., Tiikkainen, M., Häkkinen, A.-M., Hakkarainen, A., & Yki-Järvinen, H. (2007) · American Journal of Physiology-Endocrinology and Metabolism

Liver Disease Diagnosis and TreatmentDiabetes Treatment and Management

Cited by 141

Liraglutide treatment improves postprandial lipid metabolism and cardiometabolic risk factors in humans with adequately controlled type 2 diabetes: a single-centre randomized controlled study

Matikainen, N., Söderlund, S., Björnson, E., Pietiläinen, K., Hakkarainen, A., Lundbom, N., Taskinen, M., & Borén, J. (2019) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 129

Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study

Isokuortti, E., Zhou, Y., Peltonen, M., Bugianesi, E., Clement, K., Bonnefont-Rousselot, D., Lacorte, J.-M., Gastaldelli, A., Schuppan, D., Schattenberg, J. M., et al. (2017) · Diabetologia

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 120

Effects of TM6SF2 E167K on hepatic lipid and very low-density lipoprotein metabolism in humans

Borén, J., Adiels, M., Björnson, E., Matikainen, N., Söderlund, S., Rämö, J., Ståhlman, M., Ripatti, P., Ripatti, S., Palotie, A., et al. (2020) · JCI Insight

Lipid metabolism and disordersLiver Disease Diagnosis and Treatment

Cited by 81

Kinetic and Related Determinants of Plasma Triglyceride Concentration in Abdominal Obesity: Multicenter Tracer Kinetic Study

Borén, J., Watts, G. F., Adiels, M., Söderlund, S., Chan, D. C., Hakkarainen, A., Lundbom, J., Lundbom, N., Matikainen, N., Kahri, J., et al. (2015) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipid metabolism and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 72

GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance

Matikainen, N., Bogl, L. H., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Holst, J. J., & Pietiläinen, K. H. (2014) · Diabetes Care

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 63

Role of apolipoprotein C-III overproduction in diabetic dyslipidaemia

Adiels, M., Taskinen, M., Björnson, E., Andersson, L., Matikainen, N., Söderlund, S., Kahri, J., Hakkarainen, A., Lundbom, N., Sihlbom, C., et al. (2019) · Diabetes, Obesity and Metabolism

Lipid metabolism and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 55

Apolipoprotein B48 metabolism in chylomicrons and very low-density lipoproteins and its role in triglyceride transport in normo- and hypertriglyceridemic human subjects

Björnson, E., Packard, C. J., Adiels, M., Andersson, L., Matikainen, N., Söderlund, S., Kahri, J., Hakkarainen, A., Lundbom, N., Lundbom, J., et al. (2020) · Journal of Internal Medicine

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 46

Effects of liraglutide on the metabolism of triglyceride-rich lipoproteins in type 2 diabetes

Taskinen, M., Björnson, E., Matikainen, N., Söderlund, S., Pietiläinen, K. H., Ainola, M., Hakkarainen, A., Lundbom, N., Fuchs, J., Thorsell, A., et al. (2021) · Diabetes, Obesity and Metabolism

Lipid metabolism and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 40

Metabolism of sex steroids is influenced by acquired adiposity-A study of young adult male monozygotic twin pairs

Vihma, V., Naukkarinen, J., Turpeinen, U., Hämäläinen, E., Kaprio, J., Rissanen, A., Heinonen, S., Hakkarainen, A., Lundbom, J., Lundbom, N., et al. (2017) · The Journal of Steroid Biochemistry and Molecular Biology

Hormonal and reproductive studiesAdipokines, Inflammation, and Metabolic Diseases

Cited by 27