Larsen, P. Reed

Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases

Bianco, A. C., Salvatore, D., Gereben, B., Berry, M. J., & Larsen, P. R. (2002) · Endocrine Reviews

Thyroid Disorders and TreatmentsSelenium in Biological Systems

Cited by 1,853

Maternal and Fetal Thyroid Function

Epstein, F. H., Burrow, G. N., Fisher, D. A., & Larsen, P. R. (1994) · New England Journal of Medicine

Thyroid Disorders and TreatmentsBirth, Development, and Health

Cited by 720

Timing and Magnitude of Increases in Levothyroxine Requirements during Pregnancy in Women with Hypothyroidism

Alexander, E. K., Marqusee, E., Lawrence, J., Jarolim, P., Fischer, G. A., & Larsen, P. R. (2004) · New England Journal of Medicine

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 633

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

Patti, M., Houten, S. M., Bianco, A. C., Bernier, R., Larsen, P. R., Holst, J. J., Badman, M. K., Maratos‐Flier, E., Mun, E. C., Pihlajamaki, J., et al. (2009) · Obesity

Bariatric Surgery and OutcomesGut microbiota and health

Cited by 591

Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas

Huang, S. A., Tu, H. M., Harney, J. W., Venihaki, M., Butte, A. J., Kozakewich, H. P. W., Fishman, S. J., & Larsen, P. R. (2000) · New England Journal of Medicine

Thyroid Disorders and TreatmentsVascular Malformations and Hemangiomas

Cited by 540

Increased need for thyroxine during pregnancy in women with primary hypothyroidism

Mandel, S. J., Larsen, P. R., Seely, E. W., & Brent, G. A. (1990) · New England Journal of Medicine

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 360

Thyroid-Pituitary Interaction: Feedback Regulation of Thyrotropin Secretion by Thyroid Hormones

Bleich, H. L., Moore, M. J., & Larsen, P. R. (1982) · New England Journal of Medicine

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 357

An Analysis of the Sources and Quantity of 3,5,3′-Triiodothyronine Specifically Bound to Nuclear Receptors in Rat Cerebral Cortex and Cerebellum*

CRANTZ, F. R., SILVA, J. E., & LARSEN, P. R. (1982) · Endocrinology

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 340

Levothyroxine Therapy in Patients with Thyroid Disease

Mandel, S. J., Brent, G. A., & Larsen, P. R. (1993) · Annals of Internal Medicine

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 324

Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone

Tu, H. M., Kim, S.-W., Salvatore, D., Bartha, T., Legradi, G., Larsen, P. R., & Lechan, R. M. (1997) · Endocrinology

Thyroid Disorders and TreatmentsRegulation of Appetite and Obesity

Cited by 302

Molecular biological and biochemical characterization of the human type 2 selenodeiodinase.

Salvatore, D., Bartha, T., Harney, J. W., & Larsen, P. R. (1996) · Endocrinology

Thyroid Disorders and TreatmentsSelenium in Biological Systems

Cited by 284

Cerebral cortex responds rapidly to thyroid hormones

Leonard, J. L., Kaplan, M. M., Visser, T. J., Silva, J. E., & Larsen, P. R. (1981) · Science

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 206

Pituitary nuclear 3,5,3’-triiodothyronine and thyrotropin secretion: an explanation for the effect of thyroxine

Silva, J. E., & Larsen, P. R. (1977) · Science

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 198

Type 2 iodothyronine deiodinase is highly expressed in human thyroid.

Salvatore, D., Tu, H., Harney, J. W., & Larsen, P. R. (1996) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 196

The Contribution of Local Tissue Thyroxine Monodeiodination to the Nuclear 3,5,3′- Triiodothyronine in Pituitary, Liver, and Kidney of Euthyroid Rats*

SILVA, J. E., DICK, T. E., & LARSEN, P. R. (1978) · Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 189

Lipopolysaccharide Induces Type 2 Iodothyronine Deiodinase in the Mediobasal Hypothalamus: Implications for the Nonthyroidal Illness Syndrome

Fekete, C., Gereben, B., Doleschall, M., Harney, J. W., Dora, J. M., Bianco, A. C., Sarkar, S., Liposits, Z., Rand, W., Emerson, C., et al. (2004) · Endocrinology

Thyroid Disorders and TreatmentsNeuropeptides and Animal Physiology

Cited by 179

IL-6 promotes nonthyroidal illness syndrome by blocking thyroxine activation while promoting thyroid hormone inactivation in human cells

Wajner, S. M., Goemann, I. M., Bueno, A. L., Larsen, P. R., & Maia, A. L. (2011) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 168

Selective Proteolysis of Human Type 2 Deiodinase: A Novel Ubiquitin-Proteasomal Mediated Mechanism for Regulation of Hormone Activation

Gereben, B., Goncalves, C., Harney, J. W., Larsen, P. R., & Bianco, A. C. (2000) · Molecular Endocrinology

Thyroid Disorders and TreatmentsUbiquitin and proteasome pathways

Cited by 161

Triiodothyronine and Thyroxine in Hyperthyroidism COMPARISON OF THE ACUTE CHANGES DURING THERAPY WITH ANTITHYROID AGENTS

Abuid, J., & Larsen, P. R. (1974) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 156

A novel retinoid X receptor-independent thyroid hormone response element is present in the human type 1 deiodinase gene

Toyoda, N., Zavacki, A. M., Maia, A. L., Harney, J. W., & Larsen, P. R. (1995) · Molecular and Cellular Biology

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 142

Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse

Zavacki, A. M., Ying, H., Christoffolete, M. A., Aerts, G., So, E., Harney, J. W., Cheng, S.-Y., Larsen, P. R., & Bianco, A. C. (2005) · Endocrinology

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 138

The effect of diphenylhydantoin on thyroxine metabolism in man

Larsen, P. R., Atkinson, A. J., Wellman, H. N., & Goldsmith, R. E. (1970) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsPharmacological Effects and Toxicity Studies

Cited by 119

Characterization of the 5′-Flanking and 5′-Untranslated Regions of the Cyclic Adenosine 3′,5′-Monophosphate-Responsive Human Type 2 Iodothyronine Deiodinase Gene1

Bartha, T., Kim, S.-W., Salvatore, D., Gereben, B., Tu, H. M., Harney, J. W., Rudas, P., & Larsen, P. R. (2000) · Endocrinology

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 118

Atypical Expression of Type 2 Iodothyronine Deiodinase in Thyrotrophs Explains the Thyroxine-Mediated Pituitary Thyrotropin Feedback Mechanism

Christoffolete, M. A., Ribeiro, R., Singru, P., Fekete, C., da Silva, W. S., Gordon, D. F., Huang, S. A., Crescenzi, A., Harney, J. W., Ridgway, E. C., et al. (2006) · Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 118