Charo, Israel F.

The many roles of chemokines and chemokine receptors in inflammation

Charo, I. F., & Ransohoff, R. M. (2006) · New England Journal of Medicine

Chemokine receptors and signalingInflammation biomarkers and pathways

Cited by 2,523

Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis

Boring, L., Gosling, J., Cleary, M., & Charo, I. F. (1998) · Nature

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 1,965

International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors

Murphy, P. M., Baggiolini, M., Charo, I. F., Hébert, C. A., Horuk, R., Matsushima, K., Miller, L. H., Oppenheim, J. J., & Power, C. A. (2000) · Pharmacological Reviews

Chemokine receptors and signalingReceptor Mechanisms and Signaling

Cited by 1,817

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

Weisberg, S. P., Hunter, D., Huber, R., Lemieux, J., Slaymaker, S., Vaddi, K., Charo, I., Leibel, R. L., & Jr., A. W. F. (2006) · Journal of Clinical Investigation

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,497

Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites

Tsou, C.-L., Peters, W., Si, Y., Slaymaker, S., Aslanian, A. M., Weisberg, S. P., Mack, M., & Charo, I. F. (2007) · Journal of Clinical Investigation

Chemokine receptors and signalingImmune cells in cancer

Cited by 1,152

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.

Boring, L., Gosling, J., Chensue, S. W., Kunkel, S. L., Farese, R. V., Broxmeyer, H. E., & Charo, I. F. (1997) · Journal of Clinical Investigation

Chemokine receptors and signalingAtherosclerosis and Cardiovascular Diseases

Cited by 1,096

Differential roles of microglia and monocytes in the inflamed central nervous system

Yamasaki, R., Lu, H., Butovsky, O., Ohno, N., Rietsch, A. M., Cialic, R., Wu, P. M., Doykan, C. E., Lin, J., Cotleur, A. C., et al. (2014) · Journal of Experimental Medicine

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 856

Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice

Saederup, N., Cardona, A. E., Croft, K., Mizutani, M., Cotleur, A. C., Tsou, C.-L., Ransohoff, R. M., & Charo, I. F. (2010) · PLoS ONE

Chemokine receptors and signalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 599

Resistance to Experimental Autoimmune Encephalomyelitis in Mice Lacking the Cc Chemokine Receptor (Ccr2)

Izikson, L., Klein, R. S., Charo, I. F., Weiner, H. L., & Luster, A. D. (2000) · The Journal of Experimental Medicine

Multiple Sclerosis Research StudiesChemokine receptors and signaling

Cited by 584

Decreased atherosclerosis in CX3CR1–/– mice reveals a role for fractalkine in atherogenesis

Lesnik, P., Haskell, C. A., & Charo, I. F. (2003) · Journal of Clinical Investigation

Atherosclerosis and Cardiovascular DiseasesChemokine receptors and signaling

Cited by 487

CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation

Auffray, C., Fogg, D. K., Narni-Mancinelli, E., Senechal, B., Trouillet, C., Saederup, N., Leemput, J., Bigot, K., Campisi, L., Abitbol, M., et al. (2009) · Journal of Experimental Medicine

Chemokine receptors and signalingImmune cells in cancer

Cited by 422

The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood

Mizutani, M., Pino, P. A., Saederup, N., Charo, I. F., Ransohoff, R. M., & Cardona, A. E. (2012) · The Journal of Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 346

The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization

Tsutsumi, C., Sonoda, K.-H., Egashira, K., Qiao, H., Hisatomi, T., Nakao, S., Ishibashi, M., Charo, I. F., Sakamoto, T., Murata, T., et al. (2003) · Journal of Leukocyte Biology

Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

Cited by 277

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

Ryu, J. K., Petersen, M. A., Murray, S. G., Baeten, K. M., Meyer-Franke, A., Chan, J. P., Vagena, E., Bedard, C., Machado, M. R., Coronado, P. E. R., et al. (2015) · Nature Communications

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 271

CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury

Hsieh, C. L., Niemi, E. C., Wang, S. H., Lee, C. C., Bingham, D., Zhang, J., Cozen, M. L., Charo, I., Huang, E. J., Liu, J., et al. (2014) · Journal of Neurotrauma

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 174

Chromatin remodelling drives immune cell–fibroblast communication in heart failure

Alexanian, M., Padmanabhan, A., Nishino, T., Travers, J. G., Ye, L., Pelonero, A., Lee, C. Y., Sadagopan, N., Huang, Y., Auclair, K., et al. (2024) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

Cited by 140

Differential Roles of Chemokines CCL2 and CCL7 in Monocytosis and Leukocyte Migration during West Nile Virus Infection

Bardina, S. V., Michlmayr, D., Hoffman, K. W., Obara, C. J., Sum, J., Charo, I. F., Lu, W., Pletnev, A. G., & Lim, J. K. (2015) · The Journal of Immunology

Chemokine receptors and signalingMosquito-borne diseases and control

Cited by 112