Hirose, Nobuyoshi

Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians

Sato, Y., Atarashi, K., Plichta, D. R., Arai, Y., Sasajima, S., Kearney, S. M., Suda, W., Takeshita, K., Sasaki, T., Okamoto, S., et al. (2021) · Nature

Gut microbiota and healthSteroid Chemistry and Biochemistry

Cited by 632

Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians

Hashimoto, K., Kouno, T., Ikawa, T., Hayatsu, N., Miyajima, Y., Yabukami, H., Terooatea, T., Sasaki, T., Suzuki, T., Valentine, M., et al. (2019) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologySingle-cell and spatial transcriptomics

Cited by 343

Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians

Arai, Y., Martin-Ruiz, C. M., Takayama, M., Abe, Y., Takebayashi, T., Koyasu, S., Suematsu, M., Hirose, N., & von Zglinicki, T. (2015) · EBioMedicine

Genetics, Aging, and Longevity in Model OrganismsAging and Gerontology Research

Cited by 333

Associations of cardiovascular biomarkers and plasma albumin with exceptional survival to the highest ages

Hirata, T., Arai, Y., Yuasa, S., Abe, Y., Takayama, M., Sasaki, T., Kunitomi, A., Inagaki, H., Endo, M., Morinaga, J., et al. (2020) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsFrailty in Older Adults

Cited by 138

The mitochondrial‐derived peptide MOTS ‐c: a player in exceptional longevity?

Fuku, N., Pareja‐Galeano, H., Zempo, H., Alis, R., Arai, Y., Lucia, A., & Hirose, N. (2015) · Aging Cell

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 98

ApoE gene and exceptional longevity: Insights from three independent cohorts

Garatachea, N., Emanuele, E., Calero, M., Fuku, N., Arai, Y., Abe, Y., Murakami, H., Miyachi, M., Yvert, T., Verde, Z., et al. (2014) · Experimental Gerontology

Genetic Associations and EpidemiologyAlzheimer's disease research and treatments

Cited by 84

Adipokines and Aging: Findings From Centenarians and the Very Old

Arai, Y., Kamide, K., & Hirose, N. (2019) · Frontiers in Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 71

Serum insulin-like growth factor-1 in centenarians: implications of IGF-1 as a rapid turnover protein

Arai, Y., Hirose, N., Yamamura, K., Shimizu, K.-I., Takayama, M., Ebihara, Y., & Osono, Y. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Growth Hormone and Insulin-like Growth FactorsNutrition and Health in Aging

Cited by 62

Age related variation of salivary testosterone values in healthy Japanese males

Uchida, A., Bribiescas, R. G., Ellison, P. T., Kanamori, M., Ando, J., Hirose, N., & Ono, Y. (2006) · The Aging Male

Hormonal and reproductive studiesSperm and Testicular Function

Cited by 39

Outcomes of Thyroid Dysfunction in People Aged Eighty Years and Older: An Individual Patient Data Meta-Analysis of Four Prospective Studies (Towards Understanding Longitudinal International Older People Studies Consortium)

Du Puy, R. S., Poortvliet, R. K. E., Mooijaart, S. P., den Elzen, W. P. J., Jagger, C., Pearce, S. H. S., Arai, Y., Hirose, N., Teh, R., Menzies, O., et al. (2021) · Thyroid®

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 27

Accuracy of the centenarian numbers in Okinawa and the role of the Okinawan diet on longevity

Robine, J.-M., Herrmann, F. R., Arai, Y., Willcox, D. C., Gondo, Y., Hirose, N., Suzuki, M., & Saito, Y. (2013) · Experimental Gerontology

Insurance, Mortality, Demography, Risk ManagementGenetics, Aging, and Longevity in Model Organisms

Cited by 12