Crowley, William F.

The GPR54 Gene as a Regulator of Puberty

Seminara, S. B., Messager, S., Chatzidaki, E. E., Thresher, R. R., Acierno, J. S., Shagoury, J. K., Bo-Abbas, Y., Kuohung, W., Schwinof, K. M., Hendrick, A. G., et al. (2003) · New England Journal of Medicine

Hypothalamic control of reproductive hormonesSexual Differentiation and Disorders

Cited by 2,557

Central challenges facing the national clinical research enterprise

Sung, N. S., Crowley, W. F., Genel, M., Salber, P., Sandy, L., Sherwood, L. M., Johnson, S. B., Catanese, V., Tilson, H., Getz, K., et al. (2003) · JAMA

Health and Medical Research ImpactsEthics in Clinical Research

Cited by 1,235

Characterization of the physiological pattern of episodic gonadotropin secretion throughout the human menstrual cycle

FILICORI, M., SANTORO, N., MERRIAM, G. R., & CROWLEY, W. F. (1986) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesReproductive Biology and Fertility

Cited by 489

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

Pitteloud, N., Quinton, R., Pearce, S., Raivio, T., Acierno, J., Dwyer, A., Plummer, L., Hughes, V., Seminara, S., Cheng, Y.-Z., et al. (2007) · Journal of Clinical Investigation

Hypothalamic control of reproductive hormonesSexual Differentiation and Disorders

Cited by 379

TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood

Gianetti, E., Tusset, C., Noel, S. D., Au, M. G., Dwyer, A. A., Hughes, V. A., Abreu, A. P., Carroll, J., Trarbach, E., Silveira, L. F. G., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesSexual Differentiation and Disorders

Cited by 294

Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism

Miraoui, H., Dwyer, A. A., Sykiotis, G. P., Plummer, L., Chung, W., Feng, B., Beenken, A., Clarke, J., Pers, T. H., Dworzynski, P., et al. (2013) · The American Journal of Human Genetics

Hypothalamic control of reproductive hormonesGenomics and Rare Diseases

Cited by 267

Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism

Pitteloud, N., Zhang, C., Pignatelli, D., Li, J.-D., Raivio, T., Cole, L. W., Plummer, L., Jacobson-Dickman, E. E., Mellon, P. L., Zhou, Q.-Y., et al. (2007) · Proceedings of the National Academy of Sciences

Hypothalamic control of reproductive hormonesOlfactory and Sensory Function Studies

Cited by 264

A genetic basis for functional hypothalamic amenorrhea

Caronia, L. M., Martin, C., Welt, C. K., Sykiotis, G. P., Quinton, R., Thambundit, A., Avbelj, M., Dhruvakumar, S., Plummer, L., Hughes, V. A., et al. (2011) · New England Journal of Medicine

Hypothalamic control of reproductive hormonesPituitary Gland Disorders and Treatments

Cited by 256

Hypogonadotropic disorders in men and women: diagnosis and therapy with pulsatile gonadotropin-releasing hormone

SANTORO, N., FILICORI, M., & CROWLEY, W. F. (1986) · Endocrine Reviews

Hypothalamic control of reproductive hormonesGrowth Hormone and Insulin-like Growth Factors

Cited by 255

Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism

Pitteloud, N., Acierno, J. S., Meysing, A., Eliseenkova, A. V., Ma, J., Ibrahimi, O. A., Metzger, D. L., Hayes, F. J., Dwyer, A. A., Hughes, V. A., et al. (2006) · Proceedings of the National Academy of Sciences

Hypothalamic control of reproductive hormonesPituitary Gland Disorders and Treatments

Cited by 242

Mutations in Prokineticin 2 and Prokineticin receptor 2 genes in Human Gonadotrophin-Releasing Hormone Deficiency: Molecular Genetics and Clinical Spectrum

Cole, L. W., Sidis, Y., Zhang, C., Quinton, R., Plummer, L., Pignatelli, D., Hughes, V. A., Dwyer, A. A., Raivio, T., Hayes, F. J., et al. (2008) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesOlfactory and Sensory Function Studies

Cited by 208

Adult-onset idiopathic hypogonadotropic hypogonadism--a treatable form of male infertility

Nachtigall, L. B., Boepple, P. A., Pralong, F. P., & Crowley, W. F. (1997) · New England Journal of Medicine

Hypothalamic control of reproductive hormonesHormonal and reproductive studies

Cited by 199

Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes

Pitteloud, N., Meysing, A., Quinton, R., Acierno, J. S., Dwyer, A. A., Plummer, L., Fliers, E., Boepple, P., Hayes, F., Seminara, S., et al. (2006) · Molecular and Cellular Endocrinology

Hypothalamic control of reproductive hormonesGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 198

Heparan sulfate 6-O-sulfotransferase 1 , a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism

Tornberg, J., Sykiotis, G. P., Keefe, K., Plummer, L., Hoang, X., Hall, J. E., Quinton, R., Seminara, S. B., Hughes, V., Van Vliet, G., et al. (2011) · Proceedings of the National Academy of Sciences

Hypothalamic control of reproductive hormonesProteoglycans and glycosaminoglycans research

Cited by 177

Reversible Kallmann Syndrome, Delayed Puberty, and Isolated Anosmia Occurring in a Single Family with a Mutation in the Fibroblast Growth Factor Receptor 1 Gene

Pitteloud, N., Acierno, J. S., Meysing, A. U., Dwyer, A. A., Hayes, F. J., & Crowley, W. F. (2005) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 160

The spectrum of abnormal patterns of gonadotropin-releasing hormone secretion in men with idiopathic hypogonadotropic hypogonadism: clinical and laboratory correlations

SPRATT, D. I., CARR, D. B., MERRIAM, G. R., SCULLY, R. E., RAO, P. N., & CROWLEY, W. F. (1987) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesPituitary Gland Disorders and Treatments

Cited by 153

Trial of Recombinant Follicle-Stimulating Hormone Pretreatment for GnRH-Induced Fertility in Patients with Congenital Hypogonadotropic Hypogonadism

Dwyer, A. A., Sykiotis, G. P., Hayes, F. J., Boepple, P. A., Lee, H., Loughlin, K. R., Dym, M., Sluss, P. M., Crowley, W. F., & Pitteloud, N. (2013) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesSperm and Testicular Function

Cited by 146

Kisspeptin resets the hypothalamic GnRH clock in men

Chan, Y.-M., Butler, J. P., Pinnell, N. E., Pralong, F. P., Crowley, W. F., Ren, C., Chan, K. K., & Seminara, S. B. (2011) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesNeuropeptides and Animal Physiology

Cited by 114

Functionally compromised CHD7 alleles in patients with isolated GnRH deficiency

Balasubramanian, R., Choi, J.-H., Francescatto, L., Willer, J., Horton, E. R., Asimacopoulos, E. P., Stankovic, K. M., Plummer, L., Buck, C. L., Quinton, R., et al. (2014) · Proceedings of the National Academy of Sciences

Hypothalamic control of reproductive hormonesCongenital Ear and Nasal Anomalies

Cited by 83

The long-term clinical follow-up and natural history of men with adult-onset idiopathic hypogonadotropic hypogonadism

Dwyer, A. A., Hayes, F. J., Plummer, L., Pitteloud, N., & Crowley, W. F. (2010) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesPituitary Gland Disorders and Treatments

Cited by 58

GNRHR Mutations in a Woman with Idiopathic Hypogonadotropic Hypogonadism Highlight the Differential Sensitivity of Luteinizing Hormone and Follicle-Stimulating Hormone to Gonadotropin-Releasing Hormone

Meysing, A. U., Kanasaki, H., Bedecarrats, G. Y., Acierno, J. S., Conn, P. M., Martin, K. A., Seminara, S. B., Hall, J. E., Crowley, W. F., & Kaiser, U. B. (2004) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesGrowth Hormone and Insulin-like Growth Factors

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When Genetic Load Does Not Correlate with Phenotypic Spectrum: Lessons from the GnRH Receptor (GNRHR)

Gianetti, E., Hall, J. E., Au, M. G., Kaiser, U. B., Quinton, R., Stewart, J. A., Metzger, D. L., Pitteloud, N., Mericq, V., Merino, P. M., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesSexual Differentiation and Disorders

Cited by 53

Functional Hypogonadotropic Hypogonadism in Men: Underlying Neuroendocrine Mechanisms and Natural History

Dwyer, A. A., Chavan, N. R., Lewkowitz-Shpuntoff, H., Plummer, L., Hayes, F. J., Seminara, S. B., Crowley, W. F., Pitteloud, N., & Balasubramanian, R. (2019) · The Journal of Clinical Endocrinology & Metabolism

Hypothalamic control of reproductive hormonesHormonal and reproductive studies

Cited by 41

Discovering genes essential to the hypothalamic regulation of human reproduction using a human disease model: adjusting to life in the “-omics” era

Stamou, M. I., Cox, K. H., & Crowley, W. F. (2015) · Endocrine Reviews

Hypothalamic control of reproductive hormonesGenomics and Rare Diseases

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