Richardson, James A.

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R. M., Tanaka, H., Williams, S. C., Richardson, J. A., Kozlowski, G. P., Wilson, S., et al. (1998) · Cell

Regulation of Appetite and ObesitySleep and Wakefulness Research

Cited by 5,501

Narcolepsy in orexin Knockout Mice

Chemelli, R. M., Willie, J. T., Sinton, C. M., Elmquist, J. K., Scammell, T., Lee, C., Richardson, J. A., Williams, S. C., Xiong, Y., Kisanuki, Y., et al. (1999) · Cell

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 3,095

Transient Regenerative Potential of the Neonatal Mouse Heart

Porrello, E. R., Mahmoud, A. I., Simpson, E., Hill, J. A., Richardson, J. A., Olson, E. N., & Sadek, H. A. (2011) · Science

Congenital heart defects researchTissue Engineering and Regenerative Medicine

Cited by 2,545

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

Inagaki, T., Choi, M., Moschetta, A., Peng, L., Cummins, C. L., McDonald, J. G., Luo, G., Jones, S. A., Goodwin, B., Richardson, J. A., et al. (2005) · Cell Metabolism

Drug Transport and Resistance MechanismsFibroblast Growth Factor Research

Cited by 1,865

Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2

Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R. E., Richardson, J. A., & Herz, J. (1999) · Cell

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 1,261

Tie2-Cre Transgenic Mice: A New Model for Endothelial Cell-Lineage Analysis in Vivo

Kisanuki, Y. Y., Hammer, R. E., Miyazaki, J.-I., Williams, S. C., Richardson, J. A., & Yanagisawa, M. (2001) · Developmental Biology

Congenital heart defects researchDevelopmental Biology and Gene Regulation

Cited by 1,241

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

Inagaki, T., Moschetta, A., Lee, Y.-K., Peng, L., Zhao, G., Downes, M., Yu, R. T., Shelton, J. M., Richardson, J. A., Repa, J. J., et al. (2006) · Proceedings of the National Academy of Sciences

Drug Transport and Resistance MechanismsGut microbiota and health

Cited by 1,164

A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance

van Rooij, E., Quiat, D., Johnson, B. A., Sutherland, L. B., Qi, X., Richardson, J. A., Kelm, R. J., & Olson, E. N. (2009) · Developmental Cell

Muscle Physiology and DisordersMicroRNA in disease regulation

Cited by 960

Hippo pathway effector Yap promotes cardiac regeneration

Xin, M., Kim, Y., Sutherland, L. B., Murakami, M., Qi, X., McAnally, J., Porrello, E. R., Mahmoud, A. I., Tan, W., Shelton, J. M., et al. (2013) · Proceedings of the National Academy of Sciences

Congenital heart defects researchHippo pathway signaling and YAP/TAZ

Cited by 895

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

Shimomura, I., Hammer, R. E., Richardson, J. A., Ikemoto, S., Bashmakov, Y., Goldstein, J. L., & Brown, M. S. (1998) · Genes & Development

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 790

Distinct Narcolepsy Syndromes in Orexin Receptor-2 and Orexin Null Mice

Willie, J. T., Chemelli, R. M., Sinton, C. M., Tokita, S., Williams, S. C., Kisanuki, Y. Y., Marcus, J. N., Lee, C., Elmquist, J. K., Kohlmeier, K. A., et al. (2003) · Neuron

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 645

Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21

Hatley, M. E., Patrick, D. M., Garcia, M. R., Richardson, J. A., Bassel-Duby, R., van Rooij, E., & Olson, E. N. (2010) · Cancer Cell

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 626

Cytochrome c Deficiency Causes Embryonic Lethality and Attenuates Stress-Induced Apoptosis

Li, K., Li, Y., Shelton, J. M., Richardson, J. A., Spencer, E., Chen, Z. J., Wang, X., & Williams, R. S. (2000) · Cell

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 509

Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1−/− mice.

Scortegagna, M., Ding, K., Oktay, Y., Gaur, A., Thurmond, F., Yan, L.-J., Marck, B. T., Matsumoto, A. M., Shelton, J. M., Richardson, J. A., et al. (2003) · Nature Genetics

Cancer, Hypoxia, and MetabolismRedox biology and oxidative stress

Cited by 496

Interactions of the Low Density Lipoprotein Receptor Gene Family with Cytosolic Adaptor and Scaffold Proteins Suggest Diverse Biological Functions in Cellular Communication and Signal Transduction

Gotthardt, M., Trommsdorff, M., Nevitt, M. F., Shelton, J., Richardson, J. A., Stockinger, W., Nimpf, J., & Herz, J. (2000) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismReceptor Mechanisms and Signaling

Cited by 450

Direct Insulin and Leptin Action on Pro-opiomelanocortin Neurons Is Required for Normal Glucose Homeostasis and Fertility

Hill, J. W., Elias, C. F., Fukuda, M., Williams, K. W., Berglund, E. D., Holland, W. L., Cho, Y.-R., Chuang, J.-C., Xu, Y., Choi, M., et al. (2010) · Cell Metabolism

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 391

MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and function

Barbosa, A. C., Kim, M.-S., Ertunc, M., Adachi, M., Nelson, E. D., McAnally, J., Richardson, J. A., Kavalali, E. T., Monteggia, L. M., Bassel-Duby, R., et al. (2008) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 303

The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker

Mieda, M., Williams, S. C., Richardson, J. A., Tanaka, K., & Yanagisawa, M. (2006) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 290

Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2

Nakagawa, O., Arnold, M., Nakagawa, M., Hamada, H., Shelton, J. M., Kusano, H., Harris, T. M., Childs, G., Campbell, K. P., Richardson, J. A., et al. (2005) · Genes & Development

Muscle Physiology and DisordersGenomics and Chromatin Dynamics

Cited by 125

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin.

Engelking, L. J., Evers, B. M., Richardson, J. A., Goldstein, J. L., Brown, M. S., & Liang, G. (2006) · Journal of Clinical Investigation

Cleft Lip and Palate ResearchCholesterol and Lipid Metabolism

Cited by 82

Steroid 5α-reductase 1 promotes 5α-androstane-3α,17β-diol synthesis in immature mouse testes by two pathways

Mahendroo, M., Wilson, J. D., Richardson, J. A., & Auchus, R. J. (2004) · Molecular and Cellular Endocrinology

Sperm and Testicular FunctionSexual Differentiation and Disorders

Cited by 75

The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner

Hwang, S.-H., White, K. A., Somatilaka, B. N., Shelton, J. M., Richardson, J. A., & Mukhopadhyay, S. (2018) · Development

Hedgehog Signaling Pathway StudiesGenetic and Kidney Cyst Diseases

Cited by 60