Rotter, Varda

When mutants gain new powers: News from the mutant p53 field

Brosh, R., & Rotter, V. (2009) · Nature Reviews Cancer

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 1,132

Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis

Rivlin, N., Brosh, R., Oren, M., & Rotter, V. (2011) · Genes & Cancer

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 1,033

Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

Hofseth, L. J., Saito, S., Hussain, S. P., Espey, M. G., Miranda, K. M., Araki, Y., Jhappan, C., Higashimoto, Y., He, P., Linke, S. P., et al. (2003) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysRedox biology and oxidative stress

Cited by 355

Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues

Landan, G., Cohen, N. M., Mukamel, Z., Bar, A., Molchadsky, A., Brosh, R., Horn-Saban, S., Zalcenstein, D. A., Goldfinger, N., Zundelevich, A., et al. (2012) · Nature Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 305

Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery

Stock, K., Estrada, M. F., Vidic, S., Gjerde, K., Rudisch, A., Santo, V. E., Barbier, M., Blom, S., Arundkar, S. C., Selvam, I., et al. (2016) · Scientific Reports

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 253

Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53

Stambolsky, P., Tabach, Y., Fontemaggi, G., Weisz, L., Maor-Aloni, R., Sigfried, Z., Shiff, I., Kogan, I., Shay, M., Kalo, E., et al. (2010) · Cancer Cell

Cancer-related Molecular PathwaysVitamin D Research Studies

Cited by 245

Regulation of AIF expression by p53

Stambolsky, P., Weisz, L., Shats, I., Klein, Y., Goldfinger, N., Oren, M., & Rotter, V (2006) · Cell Death & Differentiation

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 194

Change of the Death Pathway in Senescent Human Fibroblasts in Response to DNA Damage Is Caused by an Inability To Stabilize p53

Seluanov, A., Gorbunova, V., Falcovitz, A., Sigal, A., Milyavsky, M., Zurer, I., Shohat, G., Goldfinger, N., & Rotter, V. (2001) · Molecular and Cellular Biology

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 178

Principles of signaling pathway modulation for enhancing human naive pluripotency induction

Bayerl, J., Ayyash, M., Shani, T., Manor, Y. S., Gafni, O., Massarwa, R., Kalma, Y., Aguilera-Castrejon, A., Zerbib, M., Amir, H., et al. (2021) · Cell stem cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 165

p53-dependent Down-regulation of Telomerase Is Mediated by p21

Shats, I., Milyavsky, M., Tang, X., Stambolsky, P., Erez, N., Brosh, R., Kogan, I., Braunstein, I., Tzukerman, M., Ginsberg, D., et al. (2004) · Journal of Biological Chemistry

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 133

Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants

Zalcenstein, A., Stambolsky, P., Weisz, L., Müller, M., Wallach, D., Goncharov, T. M., Krammer, P. H., Rotter, V., & Oren, M. (2003) · Oncogene

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 123

p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways

Buganim, Y., Solomon, H., Rais, Y., Kistner, D., Nachmany, I., Brait, M., Madar, S., Goldstein, I., Kalo, E., Adam, N., et al. (2010) · Cancer Research

Cancer-related Molecular PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 77

The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation

Tabach, Y., Milyavsky, M., Shats, I., Brosh, R., Zuk, O., Yitzhaky, A., Mantovani, R., Domany, E., Rotter, V., & Pilpel, Y. (2005) · Molecular Systems Biology

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 72

Mutant p53 protein, master regulator of human malignancies: A report on the Fifth Mutant p53 Workshop

Blandino, G., Deppert, W., Hainaut, P., Levine, A., Lozano, G., Olivier, M., Rotter, V, Wiman, K., & Oren, M. (2012) · Cell Death & Differentiation

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 34

Mutant p53 Prolongs NF-kB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

Cooks, T., Pateras, I. S., Tarcic, O., Solomon, H., Schetter, A. J., Wilder, S., Lozano, G., Pikarsky, E., Forshew, T., Rosenfeld, N., et al. (2013) · Cancer Cell

NF-κB Signaling PathwaysCancer-related Molecular Pathways

Cited by 9