Guthke, Reinhard

Gene regulatory network inference: Data integration in dynamic models—A review

Hecker, M., Lambeck, S., Toepfer, S., van Someren, E., & Guthke, R. (2009) · Biosystems

Gene Regulatory Network AnalysisMicrobial Metabolic Engineering and Bioproduction

Cited by 755

Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal

Zarse, K., Schmeisser, S., Groth, M., Priebe, S., Beuster, G., Kuhlow, D., Guthke, R., Platzer, M., Kahn, C. R., & Ristow, M. (2012) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 430

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide

Schmeisser, K., Mansfeld, J., Kuhlow, D., Weimer, S., Priebe, S., Heiland, I., Birringer, M., Groth, M., Segref, A., Kanfi, Y., et al. (2013) · Nature Chemical Biology

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 236

RNA ‐seq of the aging brain in the short‐lived fish N. furzeri – conserved pathways and novel genes associated with neurogenesis

Baumgart, M., Groth, M., Priebe, S., Savino, A., Testa, G., Dix, A., Ripa, R., Spallotta, F., Gaetano, C., Ori, M., et al. (2014) · Aging Cell

Neurogenesis and neuroplasticity mechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 167

Integrative analysis of the heat shock response in Aspergillus fumigatus

Albrecht, D., Guthke, R., Brakhage, A. A., & Kniemeyer, O. (2010) · BMC Genomics

Fungal and yeast genetics researchHeat shock proteins research

Cited by 105

Conserved senescence associated genes and pathways in primary human fibroblasts detected by RNA-seq

Marthandan, S., Baumgart, M., Priebe, S., Groth, M., Schaer, J., Kaether, C., Guthke, R., Cellerino, A., Platzer, M., Diekmann, S., et al. (2016) · PLOS ONE

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 91

Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts

Marthandan, S., Priebe, S., Baumgart, M., Groth, M., Cellerino, A., Guthke, R., Hemmerich, P., & Diekmann, S. (2015) · BioMed Research International

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 47

Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence

Marthandan, S., Menzel, U., Priebe, S., Groth, M., Guthke, R., Platzer, M., Hemmerich, P., Kaether, C., & Diekmann, S. (2016) · Biological Research

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 39

Comparative Genomics of Serial Candida glabrata Isolates and the Rapid Acquisition of Echinocandin Resistance during Therapy

Barber, A. E., Weber, M., Kaerger, K., Linde, J., Gölz, H., Duerschmied, D., Markert, A., Guthke, R., Walther, G., & Kurzai, O. (2019) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 32

The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus

Hillmann, F., Linde, J., Beckmann, N., Cyrulies, M., Strassburger, M., Heinekamp, T., Haas, H., Guthke, R., Kniemeyer, O., & Brakhage, A. A. (2014) · Molecular Microbiology

Fungal and yeast genetics researchHemoglobin structure and function

Cited by 26

DeltaMS: a tool to track isotopologues in GC- and LC-MS data

Baumeister, T. U. H., Ueberschaar, N., Schmidt-Heck, W., Mohr, J. F., Deicke, M., Wichard, T., Guthke, R., & Pohnert, G. (2018) · Metabolomics

Metabolomics and Mass Spectrometry StudiesMass Spectrometry Techniques and Applications

Cited by 25