Yeatman, Timothy J.

Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA

Liu, M. C., Oxnard, G. R., Klein, E. A., Swanton, C., Seiden, M. V., Liu, M. C., Oxnard, G. R., Klein, E. A., Smith, D., Richards, D., et al. (2020) · Annals of Oncology

Cancer Genomics and DiagnosticsEpigenetics and DNA Methylation

Cited by 1,495

A renaissance for SRC

Yeatman, T. J. (2004) · Nature Reviews Cancer

Cancer Mechanisms and TherapyProtein Kinase Regulation and GTPase Signaling

Cited by 1,113

Activating SRC mutation in a subset of advanced human colon cancers

Irby, R. B., Mao, W., Coppola, D., Kang, J., Loubeau, J. M., Trudeau, W., Karl, R., Fujita, D. J., Jove, R., & Yeatman, T. J. (1999) · Nature Genetics

Protein Kinase Regulation and GTPase SignalingCancer Mechanisms and Therapy

Cited by 489

Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

Bowman, T., Broome, M. A., Sinibaldi, D., Wharton, W., Pledger, W. J., Sedivy, J. M., Irby, R., Yeatman, T., Courtneidge, S. A., & Jove, R. (2001) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 488

Unique Ectopic Lymph Node-Like Structures Present in Human Primary Colorectal Carcinoma Are Identified by Immune Gene Array Profiling

Coppola, D., Nebozhyn, M., Khalil, F., Dai, H., Yeatman, T., Loboda, A., & Mulé, J. J. (2011) · The American Journal of Pathology

Cancer Immunotherapy and BiomarkersColorectal Cancer Treatments and Studies

Cited by 434

lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

Lu, Y., Zhao, X., Liu, Q., Li, C., Graves-Deal, R., Cao, Z., Singh, B., Franklin, J. L., Wang, J., Hu, H., et al. (2017) · Nature Medicine

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 425

A Gene Expression Model of Intrinsic Tumor Radiosensitivity: Prediction of Response and Prognosis After Chemoradiation

Eschrich, S. A., Pramana, J., Zhang, H., Zhao, H., Boulware, D., Lee, J.-H., Bloom, G., Rocha-Lima, C., Kelley, S., Calvin, D. P., et al. (2009) · International Journal of Radiation Oncology*Biology*Physics

Breast Cancer Treatment StudiesRadiation Therapy and Dosimetry

Cited by 360

EMT is the dominant program in human colon cancer

Loboda, A., Nebozhyn, M. V., Watters, J. W., Buser, C. A., Shaw, P. M., Huang, P. S., Van't Veer, L., Tollenaar, R. A., Jackson, D. B., Agrawal, D., et al. (2011) · BMC Medical Genomics

Gene expression and cancer classificationCancer Cells and Metastasis

Cited by 274

A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC

Schell, M. J., Yang, M., Teer, J. K., Lo, F. Y., Madan, A., Coppola, D., Monteiro, A. N. A., Nebozhyn, M. V., Yue, B., Loboda, A., et al. (2016) · Nature Communications

Genetic factors in colorectal cancerColorectal Cancer Treatments and Studies

Cited by 207

Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential

Mao, W., Irby, R., Coppola, D., Fu, L., Wloch, M., Turner, J., Yu, H., Garcia, R., Jove, R., & Yeatman, T. J. (1997) · Oncogene

Protein Kinase Regulation and GTPase SignalingHER2/EGFR in Cancer Research

Cited by 200

Regulation of MDMX Expression by Mitogenic Signaling

Gilkes, D. M., Pan, Y., Coppola, D., Yeatman, T., Reuther, G. W., & Chen, J. (2008) · Molecular and Cellular Biology

Cancer-related Molecular PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 82

Identification of Src transformation fingerprint in human colon cancer

Malek, R. L., Irby, R. B., Guo, Q. M., Lee, K., Wong, S., He, M., Tsai, J., Frank, B., Liu, E. T., Quackenbush, J., et al. (2002) · Oncogene

Cancer Mechanisms and TherapyProtein Kinase Regulation and GTPase Signaling

Cited by 81

Prevalence of clonal hematopoiesis of indeterminate potential (CHIP) measured by an ultra-sensitive sequencing assay: Exploratory analysis of the Circulating Cancer Genome Atlas (CCGA) study.

Swanton, C., Venn, O., Aravanis, A., Hubbell, E., Maddala, T., Beausang, J. F., Filippova, D., Gross, S., Jamshidi, A., Shen, L., et al. (2018) · Journal of Clinical Oncology

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 57

Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer

Li, C., Singh, B., Graves-Deal, R., Ma, H., Starchenko, A., Fry, W. H., Lu, Y., Wang, Y., Bogatcheva, G., Khan, M. P., et al. (2017) · Proceedings of the National Academy of Sciences

Colorectal Cancer Treatments and StudiesCancer Cells and Metastasis

Cited by 47

A Composite Gene Expression Signature Optimizes Prediction of Colorectal Cancer Metastasis and Outcome

Schell, M. J., Yang, M., Missiaglia, E., Delorenzi, M., Soneson, C., Yue, B., Nebozhyn, M. V., Loboda, A., Bloom, G., & Yeatman, T. J. (2016) · Clinical Cancer Research

Cancer Cells and MetastasisColorectal Cancer Treatments and Studies

Cited by 42

Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells

Timme, C. R., Gruidl, M., & Yeatman, T. J. (2013) · Apoptosis

Cell death mechanisms and regulationWnt/β-catenin signaling in development and cancer

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PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation

Davis, T. B., Yang, M., Schell, M. J., Wang, H., Ma, L., Pledger, W. J., & Yeatman, T. J. (2018) · Scientific Reports

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 27

Adaptation of a RAS pathway activation signature from FF to FFPE tissues in colorectal cancer

Omolo, B., Yang, M., Lo, F. Y., Schell, M. J., Austin, S., Howard, K., Madan, A., & Yeatman, T. J. (2016) · BMC Medical Genomics

Colorectal Cancer Treatments and StudiesGene expression and cancer classification

Cited by 25

An integrative gene expression signature analysis identifies CMS4 KRAS-mutated colorectal cancers sensitive to combined MEK and SRC targeted therapy

Yang, M., Davis, T. B., Pflieger, L., Nebozhyn, M. V., Loboda, A., Wang, H., Schell, M. J., Thota, R., Pledger, W. J., & Yeatman, T. J. (2022) · BMC Cancer

Colorectal Cancer Treatments and StudiesMelanoma and MAPK Pathways

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PTPRS drives adaptive resistance to MEK/ERK inhibitors through SRC

Davis, T. B., Yang, M., Wang, H., Lee, C., Yeatman, T. J., & Pledger, W. J. (2019) · Oncotarget

Protein Tyrosine PhosphatasesMelanoma and MAPK Pathways

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