McKercher, Scott R.

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

McKercher, S. R., Torbett, B. E., Anderson, K. L., Henkel, G. W., Vestal, D. J., Baribault, H., Klemsz, M., Feeney, A. J., Wu, G. E., Paige, C. J., et al. (1996) · The EMBO Journal

Hematopoietic Stem Cell TransplantationT-cell and B-cell Immunology

Cited by 1,130

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., & Maki, R. A. (1990) · Cell

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 954

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

Beers, D. R., Henkel, J. S., Xiao, Q., Zhao, W., Wang, J., Yen, A. A., Siklos, L., McKercher, S. R., & Appel, S. H. (2006) · Proceedings of the National Academy of Sciences

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 733

Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

Talantova, M., Sanz-Blasco, S., Zhang, X., Xia, P., Akhtar, M. W., Okamoto, S.-I., Dziewczapolski, G., Nakamura, T., Cao, G., Pratt, A. E., et al. (2013) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 600

The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence.

Karim, F. D., Urness, L. D., Thummel, C. S., Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., Maki, R. A., Gunther, C. V., & Nye, J. A. (1990) · Genes & Development

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 499

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.

Pongubala, J. M., Nagulapalli, S., Klemsz, M. J., McKercher, S. R., Maki, R. A., & Atchison, M. L. (1992) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 354

A new pattern for helix–turn–helix recognition revealed by the PU.l ETS–domain–DNA complex

Kodandapani, R., Pio, F., Ni, C.-Z., Piccialli, G., Klemsz, M., McKercher, S., Maki, R. A., & Ely, K. R. (1996) · Nature

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 315

Myeloid Development Is Selectively Disrupted in PU.1 Null Mice

Anderson, K. L., Smith, K. A., Conners, K., McKercher, S. R., Maki, R. A., & Torbett, B. E. (1998) · Blood

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 193

Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases

Nakamura, T., Prikhodko, O. A., Pirie, E., Nagar, S., Akhtar, M. W., Oh, C.-K., McKercher, S. R., Ambasudhan, R., Okamoto, S.-I., & Lipton, S. A. (2015) · Neurobiology of Disease

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 165

The transcription factor PU.1 is involved in macrophage proliferation.

Celada, A., Borràs, F. E., Soler, C., Lloberas, J., Klemsz, M., van Beveren, C., McKercher, S., & Maki, R. A. (1996) · The Journal of experimental medicine

Immune cells in cancerGenomics and Chromatin Dynamics

Cited by 152

Regulation of the PU.1 gene by distal elements

Li, Y., Okuno, Y., Zhang, P., Radomska, H. S., Chen, H.-M., Iwasaki, H., Akashi, K., Klemsz, M. J., McKercher, S. R., Maki, R. A., et al. (2001) · Blood

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 110

Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBP

Iwama, A., Zhang, P., Darlington, G. J., McKercher, S. R., Maki, R., & Tenen, D. G. (1998) · Nucleic Acids Research

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 91

New Insights on DNA Recognition by ets Proteins from the Crystal Structure of the PU.1 ETS Domain-DNA Complex

Pio, F., Kodandapani, R., Ni, C.-Z., Shepard, W., Klemsz, M., McKercher, S. R., Maki, R. A., & Ely, K. R. (1996) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 81

Eosinophilopoiesis

ACKERMAN, S. J., DU, J., XIN, F., DEKOTER, R., MCKERCHER, S., MAKI, R., SINGH, H., & YAMAGUCHI, Y. (2000) · Respiratory Medicine

Asthma and respiratory diseasesGenomics and Chromatin Dynamics

Cited by 8