Roses, Allen D.

APOE is a major susceptibility gene for Alzheimer’s disease

Roses, A. D., & Saunders, A. M. (1994) · Current Opinion in Biotechnology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 108

Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: The allele E3 is neuroprotective whereas E4 increases fatalities

Sabo, T., Lomnitski, L., Nyska, A., Beni, S., Maronpot, R. R., Shohami, E., Roses, A. D., & Michaelson, D. M. (2000) · Neuroscience

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 104

Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture.

Teter, B., Xu, P. ‐., Gilbert, J. R., Roses, A. D., Galasko, D., & Cole, G. M. (1999) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsNeurogenesis and neuroplasticity mechanisms

Cited by 88

On the discovery of the genetic association of apolipoprotein E genotypes and common late-onset Alzheimer disease

Roses, A. D. (2006) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 86

Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons

Brodbeck, J., Balestra, M. E., Saunders, A. M., Roses, A. D., Mahley, R. W., & Huang, Y. (2008) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 86

Defective neuronal sprouting by human apolipoprotein E4 is a gain-of-negative function.

Teter, B., Xu, P., Gilbert, J. R., Roses, A. D., Galasko, D., & Cole, G. M. (2002) · Journal of Neuroscience Research

Alzheimer's disease research and treatmentsNerve injury and regeneration

Cited by 74

Understanding the genetics of APOE and TOMM40 and role of mitochondrial structure and function in clinical pharmacology of Alzheimer's disease

Roses, A., Sundseth, S., Saunders, A., Gottschalk, W., Burns, D., & Lutz, M. (2016) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 70

Using genetics to enable studies on the prevention of Alzheimer's disease

Crenshaw, D. G., Gottschalk, W. K., Lutz, M. W., Grossman, I., Saunders, A. M., Burke, J. R., Welsh-Bohmer, K. A., Brannan, S. K., Burns, D. K., & Roses, A. D. (2013) · Clinical Pharmacology & Therapeutics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 70

Longitudinal modeling of cognitive aging and the TOMM40 effect

Caselli, R. J., Dueck, A. C., Huentelman, M. J., Lutz, M. W., Saunders, A. M., Reiman, E. M., & Roses, A. D. (2012) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 69

Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease

Welsh‐Bohmer, K. A., Gearing, M., Saunders, A. M., Roses, A. D., & Mirra, S. (1997) · Annals of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 67

Novel polymorphism in the A4 region of the amyloid precursor protein gene in a patient without Alzheimer's disease

Peacock, M. L., Warren, J. T., Roses, A. D., & Fink, J. K. (1993) · Neurology

Alzheimer's disease research and treatmentsGenetic Associations and Epidemiology

Cited by 66

TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial

Roses, A. D., Lutz, M. W., Crenshaw, D. G., Grossman, I., Saunders, A. M., & Gottschalk, W. K. (2013) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging

Hayden, K. M., McEvoy, J. M., Linnertz, C., Attix, D., Kuchibhatla, M., Saunders, A. M., Lutz, M. W., Welsh‐Bohmer, K. A., Roses, A. D., & Chiba‐Falek, O. (2012) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 53

Alzheimer’s disease: diagnostics, prognostics and the road to prevention

Grossman, I., Lutz, M. W., Crenshaw, D. G., Saunders, A. M., Burns, D. K., & Roses, A. D. (2010) · EPMA Journal

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 37

A genetics-based biomarker risk algorithm for predicting risk of Alzheimer's disease

Lutz, M. W., Sundseth, S. S., Burns, D. K., Saunders, A. M., Hayden, K. M., Burke, J. R., Welsh‐Bohmer, K. A., Roses, A. D., & Initiative, A. D. N. (2016) · Alzheimer's & Dementia: Translational Research & Clinical Interventions

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 30