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Multi-functional role of apolipoprotein E in neurodegenerative diseases

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The presence of apoE4, not the absence of apoE3, contributes to AD pathology

Teter, B., Raber, J., Nathan, B., & Crutcher, K. A. (2002) · Journal of Alzheimer's Disease · doi:10.3233/jad-2002-4305 · Cited by 37 · see citing works

Altered PET Functional Brain Responses in Cognitively Intact Elderly Persons at Risk for Alzheimer Disease (Carriers of the 4 Allele)

Scarmeas, N., Habeck, C. G., Anderson, K. E., Hilton, J., Devanand, D. P., Pelton, G. H., Tabert, M. H., Flynn, J., Park, A., Ciappa, A., et al. (2004) · American Journal of Geriatric Psychiatry · doi:10.1176/appi.ajgp.12.6.596 · Cited by 37 · see citing works

A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice

Blain, J., Sullivan, P. M., & Poirier, J. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.08.010 · Cited by 35 · see citing works

The distribution of apolipoprotein E in mouse olfactory epithelium

Nathan, B. P., Nannapaneni, S., Gairhe, S., Nwosu, I. C., & Struble, R. G. (2006) · Brain Research · doi:10.1016/j.brainres.2006.12.036 · Cited by 31 · see citing works

Apolipoprotein E may be a critical factor in hormone therapy neuroprotection

Robert, G. S. (2008) · Frontiers in bioscience · doi:10.2741/3088 · Cited by 29 · see citing works

Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins

Matsuo, M., Campenot, R. B., Vance, D. E., Ueda, K., & Vance, J. E. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.10.004 · Cited by 30 · see citing works

Delayed olfactory nerve regeneration in ApoE-deficient mice

Nathan, B. P., Nisar, R., Short, J. L., Randall, S., Grissom, E. M., Griffin, G., Switzer, P. V., & Struble, R. G. (2005) · Brain Research · doi:10.1016/j.brainres.2005.02.011 · Cited by 30 · see citing works

Caliban's heritance and the genetics of neuronal aging

Teter, B., & Finch, C. E. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.08.005 · Cited by 26 · see citing works

Apolipoprotein E, Alzheimer disease, and African Americans

Mayeux, R. (2003) · Archives of Neurology · doi:10.1001/archneur.60.2.161 · Cited by 26 · see citing works

A modified roller method for organotypic brain cultures: free-floating slices of postnatal rat hippocampus

Victorov, I. V., Lyjin, A. A., & Aleksandrova, O. P. (2001) · Brain Research Protocols · doi:10.1016/s1385-299x(00)00059-3 · Cited by 23 · see citing works

Intraneuronal amyloid‐β plays a role in mediating the synergistic pathological effects of apoE4 and environmental stimulation

Levi, O., Dolev, I., Belinson, H., & Michaelson, D. M. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04810.x · Cited by 22 · see citing works

Significance of Apolipoprotein E in Subarachnoid Hemorrhage: Neuronal Injury, Repair, and Therapeutic Perspectives–A Review

Lanterna, L. A., & Biroli, F. (2009) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2008.09.006 · Cited by 19 · see citing works

Increased Vulnerability to Focal Ischemic Brain Injury in Human Apolipoprotein E4 Knock‐In Mice

Mori, T., Kobayashi, M., Town, T., Fujita, S., & Asano, T. (2003) · Journal of Neuropathology and Experimental Neurology · doi:10.1093/jnen/62.3.280 · Cited by 21 · see citing works

Apolipoprotein E-Related Neurotoxicity as a Therapeutic Target for Alzheimer's Disease

Marques, M. A., & Crutcher, K. A. (2003) · Journal of Molecular Neuroscience · doi:10.1385/jmn:20:3:327 · Cited by 17 · see citing works

Reconstitution of the olfactory epithelium following injury in ApoE-deficient mice

Nathan, B. P., Gairhe, S., Nwosu, I. C., Clark, S. J., & Struble, R. G. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2010.08.001 · Cited by 16 · see citing works

Progressive changes in regulation of apolipoproteins E and J in glial cultures during postnatal development and aging

Patel, N. V., Wei, M., Wong, A., Finch, C. E., & Morgan, T. E. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.08.076 · Cited by 13 · see citing works

Influence of Hypertension on Longitudinal Changes in Brain Glucose Metabolism Was Modified by the APOE4 Allele Among Cognitively Normal Older Individuals

Zhou, R., Chen, H., Ye, F., Huang, S., & Zhang, J. (2020) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2020.00085 · Cited by 10 · see citing works

Glucocorticoids and the Aging Brain: Cause or Consequence?

Lucassen, P. J., & de Kloet, E. R. (2001) · Elsevier eBooks · doi:10.1016/b978-012351830-9/50064-0 · Cited by 10 · see citing works

Dietary fat up-regulates the apolipoprotein E mRNA level in the Zucker lean rat brain

Knight, D. S., Mahajan, D. K., & Qiao, X. (2001) · Neuroreport · doi:10.1097/00001756-200110080-00026 · Cited by 9 · see citing works

Nontraditional Signaling Mechanisms of Lipoprotein Receptors

Rebeck, G. W. (2009) · Science Signaling · doi:10.1126/scisignal.268pe28 · Cited by 8 · see citing works

Apolipoprotein E influences neuronal death and repair

Horsburgh, K. J., McColl, B. W., White, F., & McCulloch, J. (2003) · International Congress Series · doi:10.1016/s0531-5131(03)00024-4 · Cited by 6 · see citing works

Life-span influences of apoE4 on CNS function

Teter, B. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.06.028 · Cited by 6 · see citing works

Apolipoprotein E polymorphism and dendritic shape in hippocampal interneurons

Schönheit, B., Glöckner, F., & Ohm, T. G. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.03.016 · Cited by 6 · see citing works

Altered lipid metabolic homeostasis in the pathogenesis of Alzheimer’s disease

Marian, O. C., Tran, C. L., & Don, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819404-1.00023-3 · Cited by 2 · see citing works

The Pathogenesis of Alzheimer’s Disease: General Overview

Apostolova, L. G., & Cummings, J. L. (2007) · Springer eBooks · doi:10.1007/978-0-387-36534-3_1 · Cited by 5 · see citing works

The Effects of Breast Milk Versus Infant Formulae on Cognitive Development

Yum, J. (2014) · Cited by 4 · see citing works

Electrophysiological Monitoring of Hippocampal Slice Cultures Using MEA on Porous Membrane

Hakkoum, D., Müller, D., & Stoppini, L. (2006) · Springer eBooks · doi:10.1007/0-387-25858-2_5 · Cited by 3 · see citing works

Imaging studies and APOE genotype in persons at risk for Alzheimer’s disease

Scarmeas, N., & Stern, Y. (1996) · Current Psychiatry Reports · doi:10.1007/s11920-996-0057-4 · Cited by 3 · see citing works

CEREBROSPINAL FLUID CALCIUM, APOE PROTEIN AND GENOTYPE IN INDIVIDUALS WITH AND WITHOUT CEREBRAL VASOSPASM AFTER SUBARACHNOID HEMORRHAGE

Alexander, S. A. (2004) · D-Scholarship@Pitt (University of Pittsburgh)

at college age APOE related alterations in cerebral activation even

Scarmeas, N., Habeck, C. G., Hilton, J., Anderson, K. E., Flynn, J., & Stern, Y. (2005)

UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS BIOLÓGICAS PÓS-GRADUAÇÃO EM NEUROCIÊNCIAS

Cunha, M. P. (2013)

Role of Genetic Background: Influence of Apolipoprotein E Genotype in Alzheimer’s Disease and After Head Injury

Kerr, M. E., DeKosky, S. T., Kay, A., & Marion, D. W. (2001) · Springer eBooks · doi:10.1007/978-1-4615-1721-4_15

Cross Section Case Control Study for Clinical Correlates of Cognitive Impairment in Patients with Midlife Early Hypertension: Differential Effect of Antihypertensives

Elmassry, H., Nagy, N., Shorab, I., & Eid, M. (2015) · Activitas Nervosa Superior · doi:10.1007/bf03379625

Genetic influences on memory performance, memory-related brain activity, and neuroanatomy investigated with functional and structural magnetic resonance imaging

Mondadori, C. R. A. (2006) · Zurich Open Repository and Archive (University of Zurich) · doi:10.5167/uzh-163345

Variation in Neurodegeneration‐Linked Brain Regions in Young Adult APOE E4 Carriers With Spina Bifida

Jasien, J., Stout, J. A., Mikati, M. A., Anderson, R. J., Nave, B., Fuchs, H. E., Smith, B., Badea, A., & Browndyke, J. N. (2025) · Annals of the Child Neurology Society · doi:10.1002/cns3.70016

Untitled work

Cole (2000) · doi:10.1002/1097-0029(20000815)50:4

Rapid Communication Human Apolipoprotein E Isoform-Specific Differences in Neuronal Sprouting in Organotypic Hippocampal Culture

Teter, B., Xu, P. T., Gilbert, J. R., Roses, A. D., Galasko, D., & Cole, G. M. (2013)

Defective neuronal sprouting by human apolipoprotein E4 is a gain-of-negative function.

Teter, B., Xu, P., Gilbert, J. R., Roses, A. D., Galasko, D., & Cole, G. M. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10221 · Cited by 74 · see citing works

Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients

Ji, Y., Gong, Y., Gan, W., Beach, T., Holtzman, D. M., & Wisniewski, T. (2003) · Neuroscience · doi:10.1016/j.neuroscience.2003.08.007 · Cited by 189 · see citing works

Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion.

White, F., Nicoll, J. A. R., Roses, A. D., & Horsburgh, K. (2001) · Neurobiology of Disease · doi:10.1006/nbdi.2001.0401 · Cited by 128 · see citing works

Expression of Human Apolipoprotein E3 or E4 in the Brains ofApoe−/−Mice: Isoform-Specific Effects on Neurodegeneration

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