Hume, David A.

Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy

Chadarevian, J. P., Hasselmann, J., Lahian, A., Capocchi, J. K., Escobar, A., Lim, T. E., Le, L., Tu, C., Nguyen, J., Kiani Shabestari, S., et al. (2024) · Neuron

Neuroinflammation and Neurodegeneration MechanismsPluripotent Stem Cells Research

Cited by 83

Transcription Factor Tfec Contributes to the IL-4-Inducible Expression of a Small Group of Genes in Mouse Macrophages Including the Granulocyte Colony-Stimulating Factor Receptor

Rehli, M., Sulzbacher, S., Pape, S., Ravasi, T., Wells, C. A., Heinz, S., Söllner, L., El Chartouni, C., Krause, S. W., Steingrimsson, E., et al. (2005) · The Journal of Immunology

Cytokine Signaling Pathways and InteractionsImmune cells in cancer

Cited by 75

CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function

Pridans, C., Sauter, K. A., Baer, K., Kissel, H., & Hume, D. A. (2013) · Scientific Reports

Neuroinflammation and Neurodegeneration MechanismsHereditary Neurological Disorders

Cited by 74

Can DCs be distinguished from macrophages by molecular signatures?

Hume, D. A., Mabbott, N., Raza, S., & Freeman, T. C. (2013) · Nature Immunology

Immunotherapy and Immune ResponsesImmune cells in cancer

Cited by 69

The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter

Mansky, K. C., Sulzbacher, S., Purdom, G., Nelsen, L., Hume, D. A., Rehli, M., & Ostrowski, M. C. (2002) · Journal of Leukocyte Biology

Bone Metabolism and DiseasesBone and Dental Protein Studies

Cited by 51

Glucocorticoid Receptor Binding Induces Rapid and Prolonged Large-Scale Chromatin Decompaction at Multiple Target Loci

Jubb, A. W., Boyle, S., Hume, D. A., & Bickmore, W. A. (2017) · Cell Reports

Genomics and Chromatin DynamicsEstrogen and related hormone effects

Cited by 48

Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain

Bradford, B. M., McGuire, L. I., Hume, D. A., Pridans, C., & Mabbott, N. A. (2022) · Glia

Prion Diseases and Protein MisfoldingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 44

The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells

Kubosaki, A., Lindgren, G., Tagami, M., Simon, C., Tomaru, Y., Miura, H., Suzuki, T., Arner, E., Forrest, A. R. R., Irvine, K. M., et al. (2010) · Molecular Immunology

interferon and immune responsesGenomics and Chromatin Dynamics

Cited by 29