Metzger, Daniel

Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

Kato, S., Endoh, H., Masuhiro, Y., Kitamoto, T., Uchiyama, S., Sasaki, H., Masushige, S., Gotoh, Y., Nishida, E., Kawashima, H., et al. (1995) · Science

Estrogen and related hormone effectsProtein Kinase Regulation and GTPase Signaling

Cited by 1,964

Autophagy is required to maintain muscle mass.

Masiero, E., Agatea, L., Mammucari, C., Blaauw, B., Loro, E., Komatsu, M., Metzger, D., Reggiani, C., Schiaffino, S., & Sandri, M. (2009) · Cell Metabolism

Muscle Physiology and DisordersAutophagy in Disease and Therapy

Cited by 1,282

Estrogen Prevents Bone Loss via Estrogen Receptor α and Induction of Fas Ligand in Osteoclasts

Nakamura, T., Imai, Y., Matsumoto, T., Sato, S., Takeuchi, K., Igarashi, K., Harada, Y., Azuma, Y., Krust, A., Yamamoto, Y., et al. (2007) · Cell

Bone Metabolism and DiseasesEstrogen and related hormone effects

Cited by 1,013

Ligand-activated site-specific recombination in mice.

Feil, R., Brocard, J., Mascrez, B., LeMeur, M., Metzger, D., & Chambon, P. (1996) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 907

Regeneration of fat cells from myofibroblasts during wound healing

Plikus, M. V., Guerrero-Juarez, C. F., Ito, M., Li, Y. R., Dedhia, P. H., Zheng, Y., Shao, M., Gay, D. L., Ramos, R., Hsi, T.-C., et al. (2017) · Science

Wound Healing and TreatmentsHair Growth and Disorders

Cited by 584

Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase.

Metzger, D., Clifford, J., Chiba, H., & Chambon, P. (1995) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 570

Widespread negative response elements mediate direct repression by agonist-liganded glucocorticoid receptor

Surjit, M., Ganti, K. P., Mukherji, A., Ye, T., Hua, G., Metzger, D., Li, M., & Chambon, P. (2011) · Cell

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 551

Impaired skin wound healing in peroxisome proliferator–activated receptor (PPAR)α and PPAR β mutant mice

Michalik, L., Desvergne, B., Tan, N. S., Basu-Modak, S., Escher, P., Rieusset, J., Peters, J. M., Kaya, G., Gonzalez, F. J., Zakany, J., et al. (2001) · The Journal of Cell Biology

Peroxisome Proliferator-Activated ReceptorsWound Healing and Treatments

Cited by 406

Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

Kadkhodaei, B., Ito, T., Joodmardi, E., Mattsson, B., Rouillard, C., Carta, M., Muramatsu, S.-I., Sumi-Ichinose, C., Nomura, T., Metzger, D., et al. (2009) · The Journal of Neuroscience

Nuclear Receptors and SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 382

Brain masculinization requires androgen receptor function

Sato, T., Matsumoto, T., Kawano, H., Watanabe, T., Uematsu, Y., Sekine, K., Fukuda, T., Aihara, K.-I., Krust, A., Yamada, T., et al. (2004) · Proceedings of the National Academy of Sciences

Sexual Differentiation and DisordersNeuroendocrine regulation and behavior

Cited by 303

Friedreich Ataxia Mouse Models with Progressive Cerebellar and Sensory Ataxia Reveal Autophagic Neurodegeneration in Dorsal Root Ganglia

Simon, D., Seznec, H., Gansmuller, A., Carelle, N., Weber, P., Metzger, D., Rustin, P., Koenig, M., & Puccio, H. (2004) · The Journal of Neuroscience

Genetic Neurodegenerative DiseasesHereditary Neurological Disorders

Cited by 205

Brg1 is required for murine neural stem cell maintenance and gliogenesis

Matsumoto, S., Banine, F., Struve, J., Xing, R., Adams, C., Liu, Y., Metzger, D., Chambon, P., Rao, M. S., & Sherman, L. S. (2006) · Developmental Biology

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 147

LRP1 Controls Intracellular Cholesterol Storage and Fatty Acid Synthesis through Modulation of Wnt Signaling

Terrand, J., Bruban, V., Zhou, L., Gong, W., El Asmar, Z., May, P., Zurhove, K., Haffner, P., Philippe, C., Woldt, E., et al. (2009) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismLipid metabolism and biosynthesis

Cited by 143

PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo

Parisotto, M., Grelet, E., El Bizri, R., Dai, Y., Terzic, J., Eckert, D., Gargowitsch, L., Bornert, J.-M., & Metzger, D. (2018) · Journal of Experimental Medicine

Telomeres, Telomerase, and SenescenceProstate Cancer Treatment and Research

Cited by 43

Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways?

Pottecher, J., Adamopoulos, C., Lejay, A., Bouitbir, J., Charles, A.-L., Meyer, A., Singer, M., Wolff, V., Diemunsch, P., Laverny, G., et al. (2018) · Frontiers in Physiology

Cardiac Ischemia and ReperfusionCell death mechanisms and regulation

Cited by 33

γ-secretase inhibition lowers plasma triglyceride-rich lipoproteins by stabilizing the LDL receptor

Kim, K., Goldberg, I. J., Graham, M. J., Sundaram, M., Bertaggia, E., Lee, S. X., Qiang, L., Haeusler, R. A., Metzger, D., Chambon, P., et al. (2018) · Cell Metabolism

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 26

Hypoxia‐inducible factor 1A inhibition overcomes castration resistance of prostate tumors

Terzic, J., Abu el Maaty, M. A., Lutzing, R., Vincent, A., El Bizri, R., Jung, M., Keime, C., & Metzger, D. (2023) · EMBO Molecular Medicine

Prostate Cancer Treatment and ResearchCancer, Hypoxia, and Metabolism

Cited by 21