Most cited biochemistry, genetics and molecular biology papers
- Verified
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
Ye, C., Ho, D. J., Neri, M., Yang, C., Kulkarni, T., Randhawa, R., Henault, M., Mostacci, N., Farmer, P., Renner, S., et al. (2018) · Nature Communications
Single-cell and spatial transcriptomicsComputational Drug Discovery Methods
Cited by 222
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The BRENDA enzyme information system–From a database to an expert system
Schomburg, I., Jeske, L., Ulbrich, M., Placzek, S., Chang, A., & Schomburg, D. (2017) · Journal of Biotechnology
Bioinformatics and Genomic NetworksEnzyme Structure and Function
Cited by 222
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Degradation of DNA RNA Hybrids by Ribonuclease H and DNA Polymerases of Cellular and Viral Origin
Keller, W., & Crouch, R. (1972) · Proceedings of the National Academy of Sciences
DNA and Nucleic Acid ChemistryBiochemical and Molecular Research
Cited by 222
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Ionizable lipid nanoparticles for in utero mRNA delivery
Riley, R. S., Kashyap, M. V., Billingsley, M. M., White, B., Alameh, M.-G., Bose, S. K., Zoltick, P. W., Li, H., Zhang, R., Cheng, A. Y., et al. (2021) · Science Advances
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 222
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Increased glycolytic flux as an outcome of whole-genome duplication in yeast
Conant, G. C., & Wolfe, K. H. (2007) · Molecular Systems Biology
Chromosomal and Genetic VariationsFungal and yeast genetics research
Cited by 222
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Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan
Zhang, L., Dong, X., Lee, M., Maslov, A. Y., Wang, T., & Vijg, J. (2019) · Proceedings of the National Academy of Sciences
Cancer Genomics and DiagnosticsSingle-cell and spatial transcriptomics
Cited by 222
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Rodent Habenulo–Interpeduncular Pathway Expresses a Large Variety of Uncommon nAChR Subtypes, But Only the α3β4 and α3β3β4 Subtypes Mediate Acetylcholine Release
Grady, S. R., Moretti, M., Zoli, M., Marks, M. J., Zanardi, A., Pucci, L., Clementi, F., & Gotti, C. (2009) · The Journal of Neuroscience
Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research
Cited by 222
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BRCA1 Induces Antioxidant Gene Expression and Resistance to Oxidative Stress
Bae, I., Fan, S., Meng, Q., Rih, J. K., Kim, H. J., Kang, H. J., Xu, J., Goldberg, I. D., Jaiswal, A. K., & Rosen, E. M. (2004) · Cancer Research
Genomics, phytochemicals, and oxidative stressBRCA gene mutations in cancer
Cited by 222
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Generation of human embryonic stem cell‐derived mesoderm and cardiac cells using size‐specified aggregates in an oxygen‐controlled bioreactor
Niebruegge, S., Bauwens, C. L., Peerani, R., Thavandiran, N., Masse, S., Sevaptisidis, E., Nanthakumar, K., Woodhouse, K., Husain, M., Kumacheva, E., et al. (2009) · Biotechnology and Bioengineering
Pluripotent Stem Cells ResearchMesenchymal stem cell research
Cited by 222
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The ER UDPase ENTPD5 Promotes Protein N-Glycosylation, the Warburg Effect, and Proliferation in the PTEN Pathway
Fang, M., Shen, Z., Huang, S., Zhao, L., Chen, S., Mak, T. W., & Wang, X. (2010) · Cell
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 222
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Energy-Converting [NiFe] Hydrogenases from Archaea and Extremophiles: Ancestors of Complex I
Hedderich, R. (2004) · Journal of Bioenergetics and Biomembranes
Metalloenzymes and iron-sulfur proteinsAnaerobic Digestion and Biogas Production
Cited by 222
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Cytoglobin is a respiratory protein in connective tissue and neurons, which is up-regulated by hypoxia
Schmidt, M., Gerlach, F., Avivi, A., Laufs, T., Wystub, S., Simpson, J. C., Nevo, E., Saaler-Reinhardt, S., Reuss, S., Hankeln, T., et al. (2004) · Journal of Biological Chemistry
Hemoglobin structure and functionHeme Oxygenase-1 and Carbon Monoxide
Cited by 222
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Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors
Yan, Z., Zak, R., Luxton, G. W. G., Ritchie, T. C., Bantel-Schaal, U., & Engelhardt, J. F. (2002) · Journal of Virology
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 222
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Circulating miRNAs as Potential Biomarkers in Alzheimer's Disease
Galimberti, D., Villa, C., Fenoglio, C., Serpente, M., Ghezzi, L., Cioffi, S. M. G., Arighi, A., Fumagalli, G., & Scarpini, E. (2014) · Journal of Alzheimer’s Disease
MicroRNA in disease regulationDementia and Cognitive Impairment Research
Cited by 222
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CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank
Geurts, M. H., de Poel, E., Amatngalim, G. D., Oka, R., Meijers, F. M., Kruisselbrink, E., van Mourik, P., Berkers, G., de Winter-de Groot, K. M., Michel, S., et al. (2020) · Cell Stem Cell
CRISPR and Genetic EngineeringCystic Fibrosis Research Advances
Cited by 222
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The Mechanochemistry of Endocytosis
Liu, J., Sun, Y., Drubin, D. G., & Oster, G. F. (2009) · PLoS Biology
Cellular transport and secretionLipid Membrane Structure and Behavior
Cited by 222
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Targeting NEDD8-Activated Cullin-RING Ligases for the Treatment of Cancer
Soucy, T. A., Smith, P. G., & Rolfe, M. (2009) · Clinical Cancer Research
Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors
Cited by 222
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Fighting bacterial persistence: Current and emerging anti-persister strategies and therapeutics
Defraine, V., Fauvart, M., & Michiels, J. (2018) · Drug Resistance Updates
Bacterial Genetics and BiotechnologyBacterial biofilms and quorum sensing
Cited by 222
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Two long homologous retroviral sequence blocks in proximal Yq11 cause AZFa microdeletions as a result of intrachromosomal recombination events
Kamp, C. (2000) · Human Molecular Genetics
Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesSperm and Testicular Function
Cited by 222
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Concise Review: Mesenchymal Stem Cells in Neurodegenerative Diseases
Volkman, R., & Offen, D. (2017) · Stem Cells
Mesenchymal stem cell researchMultiple Sclerosis Research Studies
Cited by 222
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Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells
Crossley, M., Whitelaw, E., Perkins, A., Williams, G., Fujiwara, Y., & Orkin, S. H. (1996) · Molecular and Cellular Biology
Kruppel-like factors researchGenomics and Chromatin Dynamics
Cited by 222
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Ehlers-Danlos Syndrome, hypermobility type: an underdiagnosed hereditary connective tissue disorder with mucocutaneous, articular, and systemic manifestations
Castori, M. (2012) · ISRN Dermatology
Connective tissue disorders researchDermatological and Skeletal Disorders
Cited by 222
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Impact of the Human Cell Atlas on medicine
Rood, J. E., Maartens, A., Hupalowska, A., Teichmann, S. A., & Regev, A. (2022) · Nature Medicine
Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks
Cited by 222
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The loss of telomerase activity in highly differentiated CD8+CD28−CD27− T cells is associated with decreased Akt (Ser473) phosphorylation
Plunkett, F. J., Franzese, O., Finney, H. M., Fletcher, J. M., Belaramani, L. L., Salmon, M., Dokal, I., Webster, D., Lawson, A. D. G., & Akbar, A. N. (2007) · The Journal of Immunology
Telomeres, Telomerase, and SenescenceT-cell and B-cell Immunology
Cited by 222
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