Most cited biochemistry, genetics and molecular biology papers
- Verified
Topical Aminolevulinic Acid HCl Photodynamic Therapy
Ormrod, D., & Jarvis, B. (2000) · American Journal of Clinical Dermatology
Photodynamic Therapy Research StudiesNonmelanoma Skin Cancer Studies
Cited by 79
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siRNA-mediated knockdown of the heme synthesis and degradation pathways: Modulation of treatment effect of 5-aminolevulinic acid-based photodynamic therapy in urothelial cancer cell lines
Miyake, M., Ishii, M., Kawashima, K., Kodama, T., Sugano, K., Fujimoto, K., & Hirao, Y. (2009) · Photochemistry and Photobiology
Photodynamic Therapy Research StudiesHeme Oxygenase-1 and Carbon Monoxide
Cited by 79
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Association between a common mitochondrial DNA D-loop polycytosine variant and alteration of mitochondrial copy number in human peripheral blood cells
Liou, C.-W., Lin, T.-K., Chen, J.-B., Tiao, M.-M., Weng, S.-W., Chen, S.-D., Chuang, Y.-C., Chuang, J.-H., & Wang, P.-W. (2010) · Journal of Medical Genetics
Mitochondrial Function and PathologyGenetic Associations and Epidemiology
Cited by 79
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Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.
Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., et al. (2024) · Nature Communications
Genetic Associations and EpidemiologyThyroid Disorders and Treatments
Cited by 79
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The hypocholesterolemic agent LY295427 up-regulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBP
Janowski, B. A. (2002) · Proceedings of the National Academy of Sciences
Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism
Cited by 79
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Variability in the generation of induced pluripotent stem cells: Importance for disease modeling
Vitale, A. M., Matigian, N. A., Ravishankar, S., Bellette, B., Wood, S. A., Wolvetang, E. J., & Mackay-Sim, A. (2012) · Stem Cells Translational Medicine
Pluripotent Stem Cells ResearchMesenchymal stem cell research
Cited by 79
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Pharmacological blockade of TNFα prevents sarcopenia and prolongs survival in aging mice
Sciorati, C., Gamberale, R., Monno, A., Citterio, L., Lanzani, C., De Lorenzo, R., Ramirez, G. A., Esposito, A., Manunta, P., Manfredi, A. A., et al. (2020) · Aging
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 79
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The Development of an AAV-Based CRISPR SaCas9 Genome Editing System That Can Be Delivered to Neurons in vivo and Regulated via Doxycycline and Cre-Recombinase
Kumar, N., Stanford, W., de Solis, C., Aradhana, Abraham, N. D., Dao, T.-M. J., Thaseen, S., Sairavi, A., Gonzalez, C. U., & Ploski, J. E. (2018) · Frontiers in Molecular Neuroscience
CRISPR and Genetic EngineeringVirus-based gene therapy research
Cited by 79
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A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer
Kindler, H. L., Burris, H. A., Sandler, A. B., & Oliff, I. A. (2009) · Investigational New Drugs
Biochemical and Molecular ResearchAdenosine and Purinergic Signaling
Cited by 79
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Expression of the glucocorticoid receptor from the 1A promoter correlates with T lymphocyte sensitivity to glucocorticoid-induced cell death
Purton, J. F., Monk, J. A., Liddicoat, D. R., Kyparissoudis, K., Sakkal, S., Richardson, S. J., Godfrey, D. I., & Cole, T. J. (2004) · The Journal of Immunology
Estrogen and related hormone effectsGenomics and Chromatin Dynamics
Cited by 79
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bigSCale: an analytical framework for big-scale single-cell data
Iacono, G., Mereu, E., Guillaumet-Adkins, A., Corominas, R., Cuscó, I., Rodríguez-Esteban, G., Gut, M., Pérez-Jurado, L. A., Gut, I., & Heyn, H. (2018) · Genome Research
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 79
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A novel single-cell method provides direct evidence of persistent DNA damage in senescent cells and aged mammalian tissues
Galbiati, A., Beauséjour, C., & d'Adda di Fagagna, F. (2017) · Aging Cell
Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms
Cited by 79
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Kinesin motors and primary cilia
Verhey, K. J., Dishinger, J., & Kee, H. L. (2011) · Biochemical Society Transactions
Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances
Cited by 79
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The interaction of copper(II) and glycyl-l-histidyl-l-lysine, a growth-modulating tripeptide from plasma
Lau, S. J., & Sarkar, B. (1981) · Biochemical Journal
Protein Interaction Studies and Fluorescence AnalysisMetal complexes synthesis and properties
Cited by 79
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Potential Therapeutic Features of Human Amniotic Mesenchymal Stem Cells in Multiple Sclerosis: Immunomodulation, Inflammation Suppression, Angiogenesis Promotion, Oxidative Stress Inhibition, Neurogenesis Induction, MMPs Regulation, and Remyelination Stimulation
Abbasi-Kangevari, M., Ghamari, S.-H., Safaeinejad, F., Bahrami, S., & Niknejad, H. (2019) · Frontiers in Immunology
Mesenchymal stem cell researchMultiple Sclerosis Research Studies
Cited by 79
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RCSB Protein Data Bank: improved annotation, search and visualization of membrane protein structures archived in the PDB
Bittrich, S., Rose, Y., Segura, J., Lowe, R., Westbrook, J. D., Duarte, J. M., & Burley, S. K. (2022) · Bioinformatics
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 79
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Glycation cross-links inhibit matrix metalloproteinase-2 activation in vascular smooth muscle cells cultured on collagen lattice
Kuzuya, M., Asai, T., Kanda, S., Maeda, K., Cheng, X. W., & Iguchi, A. (2001) · Diabetologia
Protease and Inhibitor MechanismsAdvanced Glycation End Products research
Cited by 79
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L-DNAs as potenital antimessenger oligonucleotides: a reassessment
Garbesi, A., Capobinanco, M. L., Colonna, F. P., Tondelli, L., Arcamone, F., Manzini, G., hilbers, C. W., Aelen, J. M. E., & Blommers, M. J. J. (1993) · Nucleic Acids Research
DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms
Cited by 79
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Histone H3K4 and K36 Methylation, Chd1 and Rpd3S Oppose the Functions of Saccharomyces cerevisiae Spt4–Spt5 in Transcription
Quan, T. K., & Hartzog, G. A. (2010) · Genetics
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 79
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Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass
Boudsocq, F. (2002) · DNA Repair
DNA Repair MechanismsEnzyme Structure and Function
Cited by 79
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Metabolic activity in dormant conidia of Aspergillus niger and developmental changes during conidial outgrowth
Novodvorska, M., Stratford, M., Blythe, M. J., Wilson, R., Beniston, R. G., & Archer, D. B. (2016) · Fungal Genetics and Biology
Fungal and yeast genetics researchBacterial Genetics and Biotechnology
Cited by 79
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Structural basis of p38α regulation by hematopoietic tyrosine phosphatase
Francis, D. M., Różycki, B., Koveal, D., Hummer, G., Page, R., & Peti, W. (2011) · Nature Chemical Biology
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 79
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DeepPVP: phenotype-based prioritization of causative variants using deep learning
Boudellioua, I., Kulmanov, M., Schofield, P. N., Gkoutos, G. V., & Hoehndorf, R. (2019) · BMC Bioinformatics
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 79
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HIF-2α Enhances β-Catenin/TCF-Driven Transcription by Interacting with β-Catenin
Choi, H., Chun, Y.-S., Kim, T.-Y., & Park, J.-W. (2010) · Cancer Research
Wnt/β-catenin signaling in development and cancerCancer, Hypoxia, and Metabolism
Cited by 79
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