Most cited biochemistry, genetics and molecular biology papers
- Verified
An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle
Handschin, C., Rhee, J., Lin, J., Tarr, P. T., & Spiegelman, B. M. (2003) · Proceedings of the National Academy of Sciences
Muscle Physiology and DisordersAdipose Tissue and Metabolism
Cited by 729
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The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-β1
Mu, D., Cambier, S., Fjellbirkeland, L., Baron, J. L., Munger, J. S., Kawakatsu, H., Sheppard, D., Broaddus, V. C., & Nishimura, S. L. (2002) · The Journal of Cell Biology
TGF-β signaling in diseasesCell Adhesion Molecules Research
Cited by 729
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Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor
Weaver, B. A. A., Silk, A. D., Montagna, C., Verdier-Pinard, P., & Cleveland, D. W. (2007) · Cancer Cell
Microtubule and mitosis dynamicsCancer-related Molecular Pathways
Cited by 729
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TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria
Rathinam, V. A. K., Vanaja, S. K., Waggoner, L., Sokolovska, A., Becker, C., Stuart, L. M., Leong, J. M., & Fitzgerald, K. A. (2012) · Cell
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 729
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Detection and Characterization of Tumor Hypoxia Using pO 2 Histography
Vaupel, P., Höckel, M., & Mayer, A. (2007) · Antioxidants & Redox Signaling
Cancer, Hypoxia, and MetabolismCancer and biochemical research
Cited by 728
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Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators
Wilson, N. K., Foster, S. D., Wang, X., Knezevic, K., Schütte, J., Kaimakis, P., Chilarska, P. M., Kinston, S., Ouwehand, W. H., Dzierzak, E., et al. (2010) · Cell stem cell
Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation
Cited by 728
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Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation
Wang, R. C., Wei, Y., An, Z., Zou, Z., Xiao, G., Bhagat, G., White, M., Reichelt, J., & Levine, B. (2012) · Science
Autophagy in Disease and TherapyPI3K/AKT/mTOR signaling in cancer
Cited by 728
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Human skin pigmentation as an adaptation to UV radiation
Jablonski, N. G., & Chaplin, G. (2010) · Proceedings of the National Academy of Sciences
melanin and skin pigmentationSkin Protection and Aging
Cited by 728
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Unusual Resistance of Peptidyl Transferase to Protein Extraction Procedures
Noller, H. F., Hoffarth, V., & Zimniak, L. (1992) · Science
RNA and protein synthesis mechanismsRNA modifications and cancer
Cited by 728
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The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis
Oh, J., Takahashi, R., Kondo, S., Mizoguchi, A., Adachi, E., Sasahara, R. M., Nishimura, S., Imamura, Y., Kitayama, H., Alexander, D. B., et al. (2001) · Cell
Protease and Inhibitor MechanismsTGF-β signaling in diseases
Cited by 728
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A Suppressor of Two Essential Checkpoint Genes Identifies a Novel Protein that Negatively Affects dNTP Pools
Zhao, X., Muller, E. G. D., & Rothstein, R. (1998) · Molecular Cell
DNA Repair MechanismsFungal and yeast genetics research
Cited by 728
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Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions
Radhakrishnan, I., Pérez-Alvarado, G. C., Parker, D., Dyson, H. J., Montminy, M. R., & Wright, P. E. (1997) · Cell
Protein Structure and DynamicsGenomics and Chromatin Dynamics
Cited by 728
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Tracing the peopling of the world through genomics
Nielsen, R., Akey, J. M., Jakobsson, M., Pritchard, J. K., Tishkoff, S., & Willerslev, E. (2017) · Nature
Forensic and Genetic ResearchPleistocene-Era Hominins and Archaeology
Cited by 728
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Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy
Shibata, T., Ohta, T., Tong, K. I., Kokubu, A., Odogawa, R., Tsuta, K., Asamura, H., Yamamoto, M., & Hirohashi, S. (2008) · Proceedings of the National Academy of Sciences
Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress
Cited by 728
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Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
Soldner, F., Laganière, J., Cheng, A. W., Hockemeyer, D., Gao, Q., Alagappan, R., Khurana, V., Golbe, L. I., Myers, R. H., Lindquist, S., et al. (2011) · Cell
Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering
Cited by 728
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REBASE--a database for DNA restriction and modification: enzymes, genes and genomes.
Roberts, R. J., Vincze, T., Posfai, J., & Macelis, D. (2015) · Nucleic Acids Research
CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology
Cited by 728
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Telomerase and cancer therapeutics
Harley, C. B. (2008) · Nature Reviews Cancer
Telomeres, Telomerase, and SenescenceImmunotherapy and Immune Responses
Cited by 728
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Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
Koivunen, P., Lee, S., Duncan, C. G., Lopez, G., Lu, G., Ramkissoon, S., Losman, J. A., Joensuu, P., Bergmann, U., Gross, S., et al. (2012) · Nature
Cancer, Hypoxia, and MetabolismGlioma Diagnosis and Treatment
Cited by 727
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LNA (Locked Nucleic Acid): High-Affinity Targeting of Complementary RNA and DNA
Vester, B., & Wengel, J. (2004) · Biochemistry
DNA and Nucleic Acid ChemistryRNA Interference and Gene Delivery
Cited by 727
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Characterization of MicroRNA Expression Levels and Their Biological Correlates in Human Cancer Cell Lines
Gaur, A., Jewell, D. A., Liang, Y., Ridzon, D., Moore, J. H., Chen, C., Ambros, V. R., & Israel, M. A. (2007) · Cancer Research
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 727
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Association within a family of a balanced autosomal translocation with major mental illness
St Clair, D., Blackwood, D., Muir, W., Walker, M., St Clair, D., Muir, W., Carothers, A., Spowart, G., Gosden, C., & Evans, H. J. (1990) · The Lancet
Genomic variations and chromosomal abnormalitiesGenetic Associations and Epidemiology
Cited by 727
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Large-scale proteomics and phosphoproteomics of urinary exosomes
Gonzales, P. A., Pisitkun, T., Hoffert, J. D., Tchapyjnikov, D., Star, R. A., Kleta, R., Wang, N. S., & Knepper, M. A. (2009) · Journal of the American Society of Nephrology
Extracellular vesicles in diseaseAdvanced Proteomics Techniques and Applications
Cited by 727
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Mechanisms of Taxol resistance related to microtubules
Orr, G. A., Verdier-Pinard, P., McDaid, H., & Horwitz, S. B. (2003) · Oncogene
Microtubule and mitosis dynamicsCancer Treatment and Pharmacology
Cited by 727
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Engineered pegRNAs improve prime editing efficiency
Nelson, J. W., Randolph, P. B., Shen, S. P., Everette, K. A., Chen, P. J., Anzalone, A. V., An, M., Newby, G. A., Chen, J. C., Hsu, A., et al. (2022) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 727
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