Most cited biochemistry, genetics and molecular biology papers
- Verified
A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity
Walczak, C. E., Vernos, I., Mitchison, T. J., Karsenti, E., & Heald, R. (1998) · Current Biology
Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics
Cited by 396
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Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking
Shenker, N. S., Polidoro, S., van Veldhoven, K., Sacerdote, C., Ricceri, F., Birrell, M. A., Belvisi, M. G., Brown, R., Vineis, P., & Flanagan, J. M. (2013) · Human Molecular Genetics
Epigenetics and DNA MethylationSmoking Behavior and Cessation
Cited by 396
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Munc18-1 Promotes Large Dense-Core Vesicle Docking
Voets, T., Toonen, R. F., Brian, E. C., de Wit, H., Moser, T., Rettig, J., Südhof, T. C., Neher, E., & Verhage, M. (2001) · Neuron
Cellular transport and secretionExtracellular vesicles in disease
Cited by 396
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Telomerase, Cell Immortality, and Cancer
Harley, C. B., Kim, N. W., Prowse, K. R., Weinrich, S. L., Hirsch, K. S., West, M. D., Bacchetti, S., Hirte, H. W., Counter, C. M., Greider, C. W., et al. (1994) · Cold Spring Harbor Symposia on Quantitative Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 396
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Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway
Sebastián, D., Sorianello, E., Segalés, J., Irazoki, A., Ruiz‐Bonilla, V., Sala, D., Planet, E., Berenguer‐Llergo, A., Muñoz, J. P., Sánchez‐Feutrie, M., et al. (2016) · The EMBO Journal
Mitochondrial Function and PathologyAutophagy in Disease and Therapy
Cited by 396
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GeneMANIA Prediction Server 2013 Update
Zuberi, K., Franz, M., Rodriguez, H., Montojo, J., Lopes, C. T., Bader, G. D., & Morris, Q. (2013) · Nucleic Acids Research
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 396
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Shadow Enhancers Foster Robustness of Drosophila Gastrulation
Perry, M. W., Boettiger, A. N., Bothma, J. P., & Levine, M. (2010) · Current Biology
Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics
Cited by 396
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Acyl-CoA synthase ACSL4: an essential target in ferroptosis and fatty acid metabolism
Ding, K., Liu, C., Li, L., Yang, M., Jiang, N., Luo, S., & Sun, L. (2023) · Chinese Medical Journal
Ferroptosis and cancer prognosisCancer, Lipids, and Metabolism
Cited by 396
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Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome
Hinds, H. L., Ashley, C. T., Sutcliffe, J. S., Nelson, D. L., Warren, S. T., Housman, D. E., & Schalling, M. (1993) · Nature Genetics
Genetics and Neurodevelopmental DisordersWilliams Syndrome Research
Cited by 396
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Effect of smoking history on [3H]nicotine binding in human postmortem brain
Breese, C. R., Marks, M. J., Logel, J., Adams, C. E., Sullivan, B., Collins, A. C., & Leonard, S. (1997) · The Journal of Pharmacology and Experimental Therapeutics
Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation
Cited by 396
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Progress and challenges in the automated construction of Markov state models for full protein systems
Bowman, G. R., Beauchamp, K. A., Boxer, G., & Pande, V. S. (2009) · The Journal of Chemical Physics
Protein Structure and DynamicsAdvanced Physical and Chemical Molecular Interactions
Cited by 396
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Role of oxygen gradients in shaping redox relationships between the human intestine and its microbiota
Espey, M. G. (2013) · Free Radical Biology and Medicine
Gut microbiota and healthRedox biology and oxidative stress
Cited by 396
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Mitochondrial dysfunction in neurodegenerative disorders
Klemmensen, M. M., Borrowman, S. H., Pearce, C., Pyles, B., & Chandra, B. (2024) · Neurotherapeutics
Mitochondrial Function and PathologyParkinson's Disease Mechanisms and Treatments
Cited by 396
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Mitogen-activated Protein Kinase Kinase Inhibition Does Not Block the Stimulation of Glucose Utilization by Insulin
Lazar, D. F., Wiese, R. J., Brady, M. J., Mastick, C. C., Waters, S. B., Yamauchi, K., Pessin, J. E., Cuatrecasas, P., & Saltiel, A. R. (1995) · Journal of Biological Chemistry
Metabolism, Diabetes, and CancerProtein Kinase Regulation and GTPase Signaling
Cited by 396
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Selective degradation of splicing factor CAPERα by anticancer sulfonamides
Uehara, T., Minoshima, Y., Sagane, K., Sugi, N. H., Mitsuhashi, K. O., Yamamoto, N., Kamiyama, H., Takahashi, K., Kotake, Y., Uesugi, M., et al. (2017) · Nature Chemical Biology
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 396
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Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials
Xie, X., Yu, T., Li, X., Zhang, N., Foster, L. J., Peng, C., Huang, W., & He, G. (2023) · Signal Transduction and Targeted Therapy
Protein Degradation and InhibitorsComputational Drug Discovery Methods
Cited by 396
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Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates
Millard, C. J., Watson, P. J., Celardo, I., Gordiyenko, Y., Cowley, S. M., Robinson, C. V., Fairall, L., & Schwabe, J. W. R. (2013) · Molecular Cell
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 396
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Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
Huang, X., Wullschleger, S., Shpiro, N., McGuire, V. A., Sakamoto, K., Woods, Y. L., Mcburnie, W., Fleming, S., & Alessi, D. R. (2008) · Biochemical Journal
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 396
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The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability
Luongo, T. S., Lambert, J. P., Gross, P., Nwokedi, M., Lombardi, A. A., Shanmughapriya, S., Carpenter, A. C., Kolmetzky, D., Gao, E., van Berlo, J. H., et al. (2017) · Nature
Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion
Cited by 396
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Genome-wide analysis of microsatellite repeats in humans: their abundance and density in specific genomic regions
Subramanian, S., Mishra, R. K., & Singh, L. (2003) · Genome Biology
Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities
Cited by 396
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Functional and Molecular Differences between Voltage-Gated K+Channels of Fast-Spiking Interneurons and Pyramidal Neurons of Rat Hippocampus
Martina, M., Schultz, J. H., Ehmke, H., Monyer, H., & Jonas, P. (1998) · The Journal of Neuroscience
Ion channel regulation and functionNeuroscience and Neuropharmacology Research
Cited by 396
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Autism Profiles of Males With Fragile X Syndrome
Harris, S. W., Hessl, D., Goodlin-Jones, B., Ferranti, J., Bacalman, S., Barbato, I., Tassone, F., Hagerman, P. J., Herman, K., & Hagerman, R. J. (2008) · American Journal on Mental Retardation
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 396
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The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals
Joseph, A., Adhihetty, P. J., Buford, T. W., Wohlgemuth, S. E., Lees, H. A., Nguyen, L. M. ‐., Aranda, J. M., Sandesara, B. D., Pahor, M., Manini, T. M., et al. (2012) · Aging Cell
Mitochondrial Function and PathologyMuscle Physiology and Disorders
Cited by 395
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From geroscience to precision geromedicine: Understanding and managing aging
Kroemer, G., Maier, A. B., Cuervo, A. M., Gladyshev, V. N., Ferrucci, L., Gorbunova, V., Kennedy, B. K., Rando, T. A., Seluanov, A., Sierra, F., et al. (2025) · Cell
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 395
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