Most cited biochemistry, genetics and molecular biology papers
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Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine
Wang, Y., Song, W., Wang, J., Wang, T., Xiong, X., Qi, Z., Fu, W., Yang, X., & Chen, Y.-G. (2020) · Journal of Experimental Medicine
Single-cell and spatial transcriptomicsDigestive system and related health
Cited by 399
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Failure of neuronal homeostasis results in common neuropsychiatric phenotypes
Ramocki, M. B., & Zoghbi, H. Y. (2008) · Nature
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 399
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Vascular endothelial senescence: from mechanisms to pathophysiology
Erusalimsky, J. D. (2009) · Journal of Applied Physiology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 399
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Hypoxia and Serum Deprivation-Induced Apoptosis in Mesenchymal Stem Cells
Zhu, W., Chen, J., Cong, X., Hu, S., & Chen, X. (2006) · Stem Cells
Cell death mechanisms and regulationMesenchymal stem cell research
Cited by 399
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Mre11–Rad50–Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin templateThis paper is one of a selection of papers published in this Special Issue, entitled 28th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.
Williams, R. S., Williams, J. S., & Tainer, J. A. (2007) · Biochemistry and Cell Biology
DNA Repair MechanismsGenomics and Chromatin Dynamics
Cited by 399
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Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation
Tzatsos, A., & Kandror, K. V. (2006) · Molecular and Cellular Biology
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 399
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Microbiological food safety assessment of high hydrostatic pressure processing: a review
Rendueles, E., Omer, M. K., Alvseike, O., Alonso-Calleja, C., Capita, R., & Prieto, M. (2011) · LWT - Food Science and Technology
Microbial Inactivation MethodsListeria monocytogenes in Food Safety
Cited by 399
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TGF-β inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3
Liu, D., Black, B. L., & Derynck, R. (2001) · Genes & Development
TGF-β signaling in diseasesMuscle Physiology and Disorders
Cited by 399
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Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs
Study, L. C., van der Wijst, M. G. P., BIOS Consortium, Brugge, H., de Vries, D. H., Deelen, P., Swertz, M. A., & Franke, L. (2018) · Nature Genetics
Genetic Associations and EpidemiologySingle-cell and spatial transcriptomics
Cited by 399
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Autophagy in lysosomal storage disorders
Lieberman, A. P., Puertollano, R., Raben, N., Slaugenhaupt, S., Walkley, S. U., & Ballabio, A. (2012) · Autophagy
Autophagy in Disease and TherapyLysosomal Storage Disorders Research
Cited by 399
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An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans
Kurtz, C. B., Millet, Y. A., Puurunen, M. K., Perreault, M., Charbonneau, M. R., Isabella, V. M., Kotula, J. W., Antipov, E., Dagon, Y., Denney, W. S., et al. (2019) · Science Translational Medicine
Bacterial Cancer TherapyAmino Acid Enzymes and Metabolism
Cited by 399
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Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3–kinase
Terauchi, Y., Tsuji, Y., Satoh, S., Minoura, H., Murakami, K., Okuno, A., Inukai, K., Asano, T., Kaburagi, Y., Ueki, K., et al. (1999) · Nature Genetics
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 399
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Stabilization of RNA stacking by pseudouridine
Davis, D. R. (1995) · Nucleic Acids Research
RNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry
Cited by 399
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Endocrine treatment of breast cancer in women
SANTEN, R. J., MANNI, A., HARVEY, H., & REDMOND, C. (1990) · Endocrine Reviews
Breast Cancer Treatment StudiesEstrogen and related hormone effects
Cited by 399
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Satellite cells in human skeletal muscle; from birth to old age
Verdijk, L. B., Snijders, T., Drost, M., Delhaas, T., Kadi, F., & van Loon, L. J. C. (2014) · AGE
Muscle Physiology and DisordersMuscle metabolism and nutrition
Cited by 399
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Drugging RAS: know the enemy
Papke, B., & Der, C. J. (2017) · Science
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 399
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Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia
Clay, H. B., Daws, S., & Konradi, C. (2011) · International Journal of Developmental Neuroscience
Mitochondrial Function and PathologyBipolar Disorder and Treatment
Cited by 399
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Cysteine Cathepsins Trigger Caspase-dependent Cell Death through Cleavage of Bid and Antiapoptotic Bcl-2 Homologues
Droga-Mazovec, G., Bojič, L., Petelin, A., Ivanova, S., Romih, R., Repnik, U., Salvesen, G. S., Stoka, V., Turk, V., & Turk, B. (2008) · Journal of Biological Chemistry
Cell death mechanisms and regulationAutophagy in Disease and Therapy
Cited by 399
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High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population
Wagner, D. L., Amini, L., Wendering, D. J., Burkhardt, L.-M., Akyüz, L., Reinke, P., Volk, H.-D., & Schmueck-Henneresse, M. (2019) · Nature Medicine
CRISPR and Genetic EngineeringT-cell and B-cell Immunology
Cited by 399
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Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
Leppek, K., Byeon, G. W., Kladwang, W., Wayment-Steele, H. K., Kerr, C. H., Xu, A. F., Kim, D. S., Topkar, V. V., Choe, C., Rothschild, D., et al. (2022) · Nature Communications
RNA and protein synthesis mechanismsRNA Interference and Gene Delivery
Cited by 399
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Biofuels for a sustainable future
Liu, Y., Cruz-Morales, P., Zargar, A., Belcher, M. S., Pang, B., Englund, E., Dan, Q., Yin, K., & Keasling, J. D. (2021) · Cell
Microbial Metabolic Engineering and BioproductionBiofuel production and bioconversion
Cited by 399
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Control of the size of the human muscle mass
Rennie, M. J., Wackerhage, H., Spangenburg, E. E., & Booth, F. W. (2004) · Annual Review of Physiology
Muscle Physiology and DisordersMuscle metabolism and nutrition
Cited by 399
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Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
Crespo, M., Vilar, E., Tsai, S.-Y., Chang, K., Amin, S., Srinivasan, T., Zhang, T., Pipalia, N. H., Chen, H. J., Witherspoon, M., et al. (2017) · Nature Medicine
Pluripotent Stem Cells ResearchCancer Cells and Metastasis
Cited by 399
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The Effect of Primer-Template Mismatches on the Detection and Quantification of Nucleic Acids Using the 5′ Nuclease Assay
Stadhouders, R., Pas, S. D., Anber, J., Voermans, J., Mes, T. H. M., & Schutten, M. (2010) · The Journal of Molecular Diagnostics
Molecular Biology Techniques and ApplicationsDNA and Nucleic Acid Chemistry
Cited by 399
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