Most cited biochemistry, genetics and molecular biology papers
- Verified
Allelic and haplotypic association of GABRA2 with alcohol dependence
Covault, J., Gelernter, J., Hesselbrock, V., Nellissery, M., & Kranzler, H. R. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes
Cited by 273
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microRNA target prediction programs predict many false positives
Pinzón, N., Li, B., Martinez, L., Sergeeva, A., Presumey, J., Apparailly, F., & Seitz, H. (2017) · Genome Research
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 273
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Coupling between Catalytic Site and Collective Dynamics: A Requirement for Mechanochemical Activity of Enzymes
Yang, L.-W., & Bahar, I. (2005) · Structure
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 273
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Cathepsin D. Purification of isoenzymes from human and chicken liver
Barrett, A. J. (1970) · Biochemical Journal
Protease and Inhibitor MechanismsPeptidase Inhibition and Analysis
Cited by 273
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Early life adversity and telomere length: a meta-analysis
Ridout, K. K., Levandowski, M., Ridout, S. J., Gantz, L., Goonan, K., Palermo, D., Price, L. H., & Tyrka, A. R. (2018) · Molecular Psychiatry
Telomeres, Telomerase, and SenescenceChild Abuse and Trauma
Cited by 273
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Antibody targeting of E3 ubiquitin ligases for receptor degradation
Marei, H., Tsai, W.-T. K., Kee, Y.-S., Ruiz, K., He, J., Cox, C., Sun, T., Penikalapati, S., Dwivedi, P., Choi, M., et al. (2022) · Nature
Protein Degradation and InhibitorsUbiquitin and proteasome pathways
Cited by 273
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A statistical approach for identifying differential distributions in single-cell RNA-seq experiments
Korthauer, K. D., Chu, L.-F., Newton, M. A., Li, Y., Thomson, J., Stewart, R., & Kendziorski, C. (2016) · Genome Biology
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 273
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Poly(ADP-ribose) signaling in cell death
Virág, L., Robaszkiewicz, A., Rodriguez-Vargas, J. M., & Oliver, F. J. (2013) · Molecular Aspects of Medicine
Cell death mechanisms and regulationPARP inhibition in cancer therapy
Cited by 273
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cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein.
Cimprich, K. A., Shin, T. B., Keith, C. T., & Schreiber, S. L. (1996) · Proceedings of the National Academy of Sciences
DNA Repair MechanismsPI3K/AKT/mTOR signaling in cancer
Cited by 273
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Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner
Isenberg, J. S., Ridnour, L. A., Perruccio, E. M., Espey, M. G., Wink, D. A., & Roberts, D. D. (2005) · Proceedings of the National Academy of Sciences
Angiogenesis and VEGF in CancerNitric Oxide and Endothelin Effects
Cited by 273
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16S rRNA gene-based profiling of the human infant gut microbiota is strongly influenced by sample processing and PCR primer choice
Walker, A. W., Martin, J. C., Scott, P., Parkhill, J., Flint, H. J., & Scott, K. P. (2015) · Microbiome
Gut microbiota and healthInfant Nutrition and Health
Cited by 273
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The Role of p53 in Metabolic Regulation
Puzio-Kuter, A. M. (2011) · Genes & Cancer
Cancer, Hypoxia, and MetabolismCancer-related Molecular Pathways
Cited by 273
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Human catalase: looking for complete identity
Goyal, M. M., & Basak, A. (2010) · Protein & Cell
Redox biology and oxidative stressMetal-Catalyzed Oxygenation Mechanisms
Cited by 273
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The central role of inflammatory signaling in the pathogenesis of myelodysplastic syndromes
Sallman, D. A., & List, A. (2019) · Blood
Inflammasome and immune disordersAcute Myeloid Leukemia Research
Cited by 273
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A Nonenzymatic RNA Polymerase Model
Inoue, T., & Orgel, L. E. (1983) · Science
RNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry
Cited by 273
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Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice
Liu, P., Liang, S.-Q., Zheng, C., Mintzer, E., Zhao, Y. G., Ponnienselvan, K., Mir, A., Sontheimer, E. J., Gao, G., Flotte, T. R., et al. (2021) · Nature Communications
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 273
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The non-provitamin A carotenoid, lutein, inhibits NF-κB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-κB-inducing kinase pathways: Role of H2O2 in NF-κB activation
Kim, J.-H., Na, H.-J., Kim, C.-K., Kim, J.-Y., Ha, K.-S., Lee, H., Chung, H.-T., Kwon, H. J., Kwon, Y.-G., & Kim, Y.-M. (2008) · Free Radical Biology and Medicine
NF-κB Signaling PathwaysAntioxidant Activity and Oxidative Stress
Cited by 273
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Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation
Kueh, H. Y., Champhekar, A., Nutt, S. L., Elowitz, M. B., & Rothenberg, E. V. (2013) · Science
Gene Regulatory Network AnalysisDevelopmental Biology and Gene Regulation
Cited by 273
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Regulation of Muscle Mass by Follistatin and Activins
Lee, S.-J., Lee, Y.-S., Zimmers, T. A., Soleimani, A., Matzuk, M. M., Tsuchida, K., Cohn, R. D., & Barton, E. R. (2010) · Molecular Endocrinology
Muscle Physiology and DisordersTGF-β signaling in diseases
Cited by 273
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MAPK signaling in inflammation-associated cancer development
Huang, P., Han, J., & Hui, L. (2010) · Protein & Cell
Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling
Cited by 273
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Human bone marrow assessment by single-cell RNA sequencing, mass cytometry, and flow cytometry
Oetjen, K. A., Lindblad, K. E., Goswami, M., Gui, G., Dagur, P. K., Lai, C., Dillon, L. W., McCoy, J. P., & Hourigan, C. S. (2018) · JCI Insight
Single-cell and spatial transcriptomicsHematopoietic Stem Cell Transplantation
Cited by 272
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Recent developments in understanding the iron acquisition strategies of gram positive pathogens
Sheldon, J. R., & Heinrichs, D. E. (2015) · FEMS Microbiology Reviews
Bacterial Genetics and BiotechnologyIron Metabolism and Disorders
Cited by 272
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Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte
Hill, P. W. S., Leitch, H. G., Requena, C. E., Sun, Z., Amouroux, R., Roman-Trufero, M., Borkowska, M., Terragni, J., Vaisvila, R., Linnett, S., et al. (2018) · Nature
Epigenetics and DNA MethylationGenetic Syndromes and Imprinting
Cited by 272
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Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans
Keinan, A., Mullikin, J. C., Patterson, N., & Reich, D. (2007) · Nature Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 272
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