The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Impact of Atrial Fibrillation on Mortality, Stroke, and Medical Costs
Abstract
BACKGROUND: The impact of atrial fibrillation (AF) on mortality, stroke, and medical costs is unknown. METHODS: We conducted a prospective cohort study of hospitalized Medicare patients with AF and 1 other cardiovascular diagnosis (CVD) compared with a matched group without AF (n = 26,753), randomly selected in 6 age-sex strata from 1989 MedPAR files of more than 1 million patients diagnosed as having AF. Stroke rates were also determined in another cohort free of CVD (n = 14,267). Total medical costs after hospitalization were available from a 1991 cohort. Cumulative mortality, stroke rates, and costs following index admission were adjusted by multivariate and proportional hazard regression analyses. RESULTS: Mortality rates were high in individuals with CVD, ranging from 19.0% to 52.1% in 1 year. Adjusted relative mortality risk was approximately 20% higher in patients with AF in all age-sex strata during each of the 3 years studied (P < .05). Incidence of stroke was high in individuals with CVD, 6.2% to 15.4% in 1 year, with and without AF, and was at least 5-fold higher than in individuals without CVD. In those with CVD, stroke rates were approximately 25% higher in women with AF (P < .05) but only 10% higher in men. Adjusted total Medicare spending in 1 year was 8.6- to 22.6-fold greater in men, and 9.8- to 11.2-fold greater in women with AF (P < .05). Second- and third-year costs were increased as well. CONCLUSION: Prevention of AF and treatment of patients with AF and associated CVD may yield benefits in reduced mortality and stroke as well as reducing health care costs.
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Citations
Cites
Atrial fibrillation as an independent risk factor for stroke: the Framingham study
Wolf, P. A., Abbott, R. D., & Kannel, W. B. (1991) · Stroke · doi:10.1161/01.str.22.8.983 · Cited by 7,388
Self-citationCox, D. R., & Oakes, D. (2018) · Chapman & Hall/CRC eBooks · doi:10.1201/9781315137438 · Cited by 6,234
Benjamin, E. J. (1994) · JAMA · doi:10.1001/jama.1994.03510350050036 · Cited by 2,613
Feinberg, W. M. (1995) · Archives of Internal Medicine · doi:10.1001/archinte.155.5.469 · Cited by 2,274
The Interpretation of Dummy Variables in Semilogarithmic Equations
Halvorsen, R., & Palmquist, R. B. (1980) · American Economic Review · Cited by 2,015
EAFT (European Atrial Fibrillation Trial) Study Group (1993) · The Lancet · doi:10.1016/0140-6736(93)92358-z · Cited by 1,741
Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: The fiamingham Study
Wolf, P. A., Dawber, T. R., Thomas, H. E., & Kannel, W. B. (1978) · Neurology · doi:10.1212/wnl.28.10.973 · Cited by 1,526
Self-citationStroke Severity in Atrial Fibrillation: The Framingham Study
Lin, H.-J., Wolf, P. A., Kelly-Hayes, M., Beiser, A. S., Kase, C. S., Benjamin, E. J., & D'Agostino, R. B. (1996) · Stroke · doi:10.1161/01.str.27.10.1760 · Cited by 1,389
Self-citationStone, P. H., Chaitman, B. R., McMahon, R. P., Andrews, T. C., MacCallum, G., Sharaf, B., Frishman, W., Deanfield, J. E., Sopko, G., Pratt, C., et al. (1996) · Circulation · doi:10.1161/01.cir.94.7.1537 · Cited by 605
Secular trends in the prevalence of atrial fibrillation: The Framingham study
Wolf, P. A., Benhamin, E. J., Belanger, A. J., Kannel, W. B., Levy, D., & D'Agostino, R. B. (1996) · American Heart Journal · doi:10.1016/s0002-8703(96)90288-4 · Cited by 446
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Cited by
Miyasaka, Y., Barnes, M. E., Gersh, B. J., Cha, S. S., Bailey, K. R., Abhayaratna, W. P., Seward, J. B., & Tsang, T. S. M. (2006) · Circulation · doi:10.1161/circulationaha.105.595140 · Cited by 2,564
Stewart, S., Hart, C. L., Hole, D. J., & McMurray, J. J. V. (2002) · The American Journal of Medicine · doi:10.1016/s0002-9343(02)01236-6 · Cited by 1,562
Association of Atrial Fibrillation and Obstructive Sleep Apnea
Gami, A. S., Pressman, G., Caples, S. M., Kanagala, R., Gard, J. J., Davison, D. E., Malouf, J. F., Ammash, N. M., Friedman, P. A., & Somers, V. K. (2004) · Circulation · doi:10.1161/01.cir.0000136587.68725.8e · Cited by 1,148
Quality of life in patients with atrial fibrillation: a systematic review
Thrall, G., Lane, D., Carroll, D., & Lip, G. Y. H. (2006) · The American Journal of Medicine · doi:10.1016/j.amjmed.2005.10.057 · Cited by 697
Tsang, T. S. M., Gersh, B. J., Appleton, C. P., Tajik, A. J., Barnes, M. E., Bailey, K. R., Oh, J. K., Leibson, C., Montgomery, S. C., & Seward, J. B. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02373-2 · Cited by 657
Metadata
- Authors
- Wolf, P. A., Mitchell, J. B., Baker, C. S., Kannel, W. B., & D'Agostino, R. B.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1998-02-09
- Volume
- 158
- Issue
- 3
- Pages
- 229
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2008450235
- Cited by
- 687
- References
- 16
- FWCI
- 13.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wolf, P. A., Mitchell, J. B., Baker, C. S., Kannel, W. B., & D'Agostino, R. B. (1998). Impact of Atrial Fibrillation on Mortality, Stroke, and Medical Costs. Archives of Internal Medicine. https://doi.org/10.1001/archinte.158.3.229
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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