The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Risk Factors for Congestive Heart Failure in US Men and Women: NHANES I Epidemiologic Follow-up Study
Abstract
BACKGROUND: The incidence of congestive heart failure (CHF) has been increasing steadily in the United States during the past 2 decades. We studied risk factors for CHF and their corresponding attributable risk in the First National Health and Nutrition Examination Survey Epidemiologic Follow-up Study. PARTICIPANTS AND METHODS: A total of 13 643 men and women without a history of CHF at baseline examination were included in this prospective cohort study. Risk factors were measured using standard methods between 1971 and 1975. Incidence of CHF was assessed using medical records and death certificates obtained between 1982 and 1984 and in 1986, 1987, and 1992. RESULTS: During average follow-up of 19 years, 1382 CHF cases were documented. Incidence of CHF was positively and significantly associated with male sex (relative risk [RR], 1.24; 95% confidence interval [CI], 1.10-1.39; P<.001; population attributable risk [PAR], 8.9%), less than a high school education (RR, 1.22; 95% CI, 1.04-1.42; P =.01; PAR, 8.9%), low physical activity (RR, 1.23; 95% CI, 1.09-1.38; P<.001; PAR, 9.2%), cigarette smoking (RR, 1.59; 95% CI, 1.39-1.83; P<.001; PAR, 17.1%), overweight (RR, 1.30; 95% CI, 1.12-1.52; P =.001; PAR, 8.0%), hypertension (RR, 1.40; 95% CI, 1.24-1.59; P<.001; PAR, 10.1%), diabetes (RR, 1.85; 95% CI, 1.51-2.28; P<.001; PAR, 3.1%), valvular heart disease (RR, 1.46; 95% CI, 1.17-1.82; P =.001; PAR, 2.2%), and coronary heart disease (RR, 8.11; 95% CI, 6.95-9.46; P<.001; PAR, 61.6%). CONCLUSIONS: Male sex, less education, physical inactivity, cigarette smoking, overweight, diabetes, hypertension, valvular heart disease, and coronary heart disease are all independent risk factors for CHF. More than 60% of the CHF that occurs in the US general population might be attributable to coronary heart disease.
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“Similarly, in observational studies (NHANES 64 and ARIC 65 ), the incidence of HF in patients with T2DM was higher than in those without T2DM, with the corresponding hazard ratios (HRs) of 1.85 and 3.54.”
From Type 2 diabetes mellitus and heart failure: A position statement from the Heart Failure Association of the European Society of Cardiology (2018) · cites this paper as [64]
In the citing paper
“However, in human studies, we mainly have to rely on cross-sectional data at this time, and the conclusions are not firm regarding the direct role of obesity in the development of heart failure (14, 46, 132, 376).”
From Cardiac remodeling in obesity (2008) · cites this paper as [132]
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“In the American study, NHANES I [16], male sex, low education, physical inactivity, smoking, overweight, hypertension, diabetes, valvular disease and ischemic heart disease were independent predictors of developing HF, whereas high scholesterol was not.”
BackgroundResultGhosh, S., Kelly, N. O., Smith, J. M. B., Dexter, J., Carroll-Hawkins, C., & Robertson, W. (2011) · Thorax · doi:10.1136/thoraxjnl-2011-201054c.232 · Cited by 1
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Engelhardt, H., Leopold, L., & Jann, B. (2012) · Social Science Open Access Repository (GESIS – Leibniz Institute for the Social Sciences) · doi:10.7892/boris.51332 · Cited by 1
“…consistently shows that education is negatively associated with incidence of such chronic conditions as hypertension (Diez-Rouxet al., 2002), heart disease (He et al., 2001), stroke (Jakovljevic et al., 2001), heart attack (Manrique-Garcia, 2011), and cancer (Menvielle et al., 2009; Geyer, 2008).”
Smoking, Secondhand Smoke, and Cardiovascular Disease
Barnoya, J., & Glantz, S. A. (2007) · Springer eBooks · doi:10.1007/978-1-84628-715-2_130 · Cited by 1
Effects of short-term supplementation with vitamin C on lipid peroxidation in cigarette smokers.
Alsenaidy, A. M. (2010) · AUSTRALIAN JOURNAL OF BASIC AND APPLIED SCIENCES · Cited by 1
Gender Differences in Heart Failure: Concerns for Drug Development
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Risk of Heart Failure with the Use of Thiazolidinediones within a Medicaid Population
Shaya, F. T., Shin, J. Y., Mullins, C. D., Khoury, A. C. E., & Garber, H. (2015) · Cited by 1
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Lifestyle Factors and Risk of Heart Failure: A Prospective Cohort Study
Wang, Y. (2013) · doi:10.31390/gradschool_dissertations.678 · Cited by 1
“Moreover, the results of the three studies were inconsistent.(Djousse et al., 2009; He et al., 2001; Hu et al., 2010a; Kenchaiah et al., 2009) Physical activity was found to be a”
InfluentialDynamic Adaptive Remote Health Monitoring for Patients with Chronic Disease
Suh, M.-K. (2012) · eScholarship (California Digital Library) · Cited by 1
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“Finally, increased afterload on the heart due to hypertension can induce cardiac fibrosis and remodeling, which are established risk factors in several heart diseases, such as heart failure and arrhythmias (Fuchs & Whelton, 2020; He et al., 2001; Lip et al., 2017).”
BackgroundThe positive impact of the Life's Essential 8 in the prevention of incident heart failure
López-Jaramillo, P. A., López-Flecher, M., & López-López, J. (2025) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwaf066 · Cited by 1
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Medical Practice Variations in Heart Failure
Roth, G. A., Brown, J. R., & Malenka, D. J. (2013) · Springer eBooks · doi:10.1007/978-1-4899-7573-7_81-1
“These include age, coronary artery disease, cigarette smoking, hypertension, low physical activity, male sex, less high school education, and being overweight (He et al. 2001).”
BackgroundObésité et Pronostic de l’insuffisance cardiaque : le paradoxe de l’obésité, mythe ou réalité ?
Bounhoure, J., Galinier, M., Roncalli, J. G., & MASSABUAU, P. (2014) · Bulletin de l Académie Nationale de Médecine · doi:10.1016/s0001-4079(19)31377-9
Burden of Disease Attributable to Obesity and Overweight: Korean Focus
Yoon, S., & Park, J. (2009) · Springer eBooks · doi:10.1007/978-0-387-78665-0_63
Myocardial Ischemia & Viability
Camici, P. G., & Rimoldi, O. E. (2012) · Springer eBooks · doi:10.1007/978-88-470-2522-6_7
Diabetes, Blutzuckereinstellung und Herzinsuffizienz bei stabiler koronarer Herzerkrankung
Jecht, M. (2010) · Der Diabetologe · doi:10.1007/s11428-010-0644-1
Hypertension and Heart Failure Sine Heart Failure
Giles, T. D. (2003) · Journal of Clinical Hypertension · doi:10.1111/j.1524-6175.2003.02476.x
The influence of physical activity and BMI on blood pressure in African-American women
Edmonds, L. D. (2011) · D-Scholarship@Pitt (University of Pittsburgh)
Metadata
- Authors
- He, J., Ogden, L. G., Bazzano, L. A., Vupputuri, S., Loria, C., & Whelton, P. K.
- Affiliations
- Tulane University (US)
- Corresponding author
- He, Jiang
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2001-04-09
- Volume
- 161
- Issue
- 7
- Pages
- 996
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2025266397
- Cited by
- 1,172
- References
- 24
- Citations by year
- 2026: 14 · 2025: 29 · 2024: 38 · 2023: 39 · 2022: 43 · 2021: 51 · 2020: 54 · 2019: 60 · 2018: 61 · 2017: 56 · 2016: 55 · 2015: 61 · 2014: 67 · 2013: 63 · 2012: 66
- FWCI
- 17.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r03hl061954-02, 5r01hl060300-05)
- National Heart, Lung, and Blood Institute (R03 HL-61954, R01HL60300)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Keywords
- congestive heart failure, risk factors, attributable risk, incidence, sex differences, educational attainment, physical inactivity, cigarette smoking, overweight, hypertension, diabetes mellitus, valvular heart disease, coronary artery disease, coronary revascularization, coronary angioplasty, coronary artery bypass grafting, coronary angiography
- MeSH terms
- Aged, Aged, 80 and over, Coronary Disease, Death Certificates, Educational Status, Female, Follow-Up Studies, Heart Failure, Heart Valve Diseases, Humans, Hypertension, Male, Middle Aged, Nutrition Surveys, Obesity, Risk Factors, Smoking, United States, Exercise, Incidence, Proportional Hazards Models, Sex Distribution, Diabetes Complications
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