Cited by 288Clostridium difficile and Clostridium perfringens researchMicroscopic ColitisInfection Control in Healthcare

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The Spectrum of Pseudomembranous Enterocolitis and Antibiotic-Associated Diarrhea

Hurley, Brian W., Nguyen, Cuong C.·2002·Archives of Internal Medicine

DOI 10.1001/archinte.162.19.2177

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Abstract

Pseudomembranous (entero)colitis is primarily caused by Clostridium difficile infection. The most common predisposing factor is prior use of antibiotics, including vancomycin and metronidazole, which themselves are therapy for C difficile colitis. Other risk factors have also been described. The presence of C difficile in the gastrointestinal tract leads to a spectrum of manifestations from the asymptomatic carrier state to fulminant colitis. Successful treatment of C difficile colitis requires prompt treatment with appropriate antibiotics, withdrawal of the suspected predisposing antibiotics, and, in rare cases, total colectomy. Preventive measures of adequate infection control and judicious use of antibiotics are necessary means in attempting to control the spread of C difficile infection. Attempts at making an effective human vaccine are currently under way.

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Clostridium difficile Colitis
Kelly, C. P., Pothoulakis, C., & LaMont, J. T. (1994) · New England Journal of Medicine · doi:10.1056/nejm199401273300406 · Cited by 1,320
Asymptomatic Carriage ofClostridium difficileand Serum Levels of IgG Antibody against Toxin A
Kyne, L., Warny, M., Qamar, A., & Kelly, C. P. (2000) · New England Journal of Medicine · doi:10.1056/nejm200002103420604 · Cited by 932
Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/ Management
Feldman, M. L., Friedman, L. S., & Brandt, L. J. (1998) · Medical Entomology and Zoology · Cited by 735
Clindamycin-Associated Colitis
Tedesco, F. J., BARTON, R. W., & ALPERS, D. H. (1974) · Annals of Internal Medicine · doi:10.7326/0003-4819-81-4-429 · Cited by 611
Field trial of oral cholera vaccines in Bangladesh: results from three-year follow-up
Clemens, J. D., & CLEMENS, J. (1990) · The Lancet · doi:10.1016/0140-6736(90)90080-o · Cited by 508
Acquisition of Clostridium difficile by Hospitalized Patients: Evidence for Colonized New Admissions as a Source of Infection
Clabots, C., Johnson, S., Olson, M. M., Peterson, L. R., & Gerding, D. N. (1992) · The Journal of Infectious Diseases · doi:10.1093/infdis/166.3.561 · Cited by 472
Guidelines for the diagnosis and management of Clostridium difficile-associated diarrhea and colitis. American College of Gastroenterology, Practice Parameters Committee.
Fekety, R. (1997) · PubMed · Cited by 450
Clostridium difficile–Associated Diarrhea
Johnson, S., & Gerding, D. N. (1998) · Clinical Infectious Diseases · doi:10.1086/520276 · Cited by 443
Clostridium difficile Infection
Kelly, C. P., & LaMont, J. T. (1998) · Annual Review of Medicine · doi:10.1146/annurev.med.49.1.375 · Cited by 413
Primary symptomless colonisation by Clostridium difficile and decreased risk of subsequent diarrhoea
Shim, J. K., Johnson, S., Samore, M. H., Bliss, D. Z., & Gerding, D. N. (1998) · The Lancet · doi:10.1016/s0140-6736(97)08062-8 · Cited by 388

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Clostridium difficile Toxins: Mechanism of Action and Role in Disease
Voth, D. E., & Ballard, J. D. (2005) · Clinical Microbiology Reviews · doi:10.1128/cmr.18.2.247-263.2005 · Cited by 1,103
Bile Salts and Glycine as Cogerminants for Clostridium difficile Spores
Sorg, J. A., & Sonenshein, A. L. (2008) · Journal of Bacteriology · doi:10.1128/jb.01765-07 · Cited by 711
Impact of Clostridium difficile on Inflammatory Bowel Disease
Issa, M., Vijayapal, A., Graham, M. B., Beaulieu, D. B., Otterson, M. F., Lundeen, S. J., Skaros, S., Weber, L. R., KOMOROWSKI, R. A., Knox, J. F., et al. (2007) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2006.12.028 · Cited by 570
Incidence of Clostridium difficile Infection in Inflammatory Bowel Disease
Rodemann, J. F., Dubberke, E. R., Reske, K. A., Seo, D. H., & Stone, C. D. (2007) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2006.12.027 · Cited by 520
The causes of intestinal dysbiosis: a review.
Hawrelak, J. A., & Myers, S. P. (2004) · PubMed · Cited by 366
Dysbiotic Events in Gut Microbiota: Impact on Human Health
Schippa, S., & Conte, M. (2014) · Nutrients · doi:10.3390/nu6125786 · Cited by 256
Clostridium difficile toxin expression is inhibited by the novel regulator TcdC
Matamouros, S., England, P., & Dupuy, B. (2007) · Molecular Microbiology · doi:10.1111/j.1365-2958.2007.05739.x · Cited by 236
Systematic review with meta-analysis: Lactobacillus rhamnosus GG in the prevention of antibiotic-associated diarrhoea in children and adults
Szajewska, H., & Kołodziej, M. (2015) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13404 · Cited by 224
Metabolism of Bile Salts in Mice Influences Spore Germination in Clostridium difficile
Giel, J. L., Sorg, J. A., Sonenshein, A. L., & Zhu, J. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008740 · Cited by 202
Review of Current Literature on the Economic Burden ofClostridium difficileInfection
Dubberke, E. R., & Wertheimer, A. I. (2008) · Infection Control and Hospital Epidemiology · doi:10.1086/592981 · Cited by 183
The Comparative Pathology of Clostridium difficile-associated Disease
Keel, M. K., & Songer, J. G. (2006) · Veterinary Pathology · doi:10.1354/vp.43-3-225 · Cited by 166
Probiotics for the prevention of antibiotic-associated diarrhoea: A systematic review and meta-analysis
Goodman, C., Keating, G., Georgousopoulou, E., Hespe, C., & Levett, K. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-043054 · Cited by 163
Construction and analysis of chromosomal Clostridium difficile mutants
O’Connor, J. R., Lyras, D., Farrow, K. A., Adams, V., Powell, D., Hinds, J., Cheung, J. K., & Rood, J. I. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05315.x · Cited by 158
Preoperative Oral Antibiotics in Colorectal Surgery Increase the Rate of Clostridium difficile Colitis
Wren, S. M. (2005) · Archives of Surgery · doi:10.1001/archsurg.140.8.752 · Cited by 142
Clostridium difficile disease: Diagnosis, pathogenesis, and treatment update
Napolitano, L. M., & Edmiston, C. E. (2017) · Surgery · doi:10.1016/j.surg.2017.01.018 · Cited by 132
Clostridium difficileRibotype 027: Relationship to Age, Detectability of Toxins A or B in Stool With Rapid Testing, Severe Infection, and Mortality
Rao, K. K., Micić, D., Natarajan, M., Winters, S. A., Kiel, M. J., Walk, S. T., Santhosh, K., Mogle, J. A., Gałecki, A. T., LeBar, W., et al. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ254 · Cited by 127
Pathology of drug‐associated gastrointestinal disease
Price, A. B. (2003) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.2003.01980.x · Cited by 121
Clostridium difficile‐associated diarrhoea
Elliott, B., Chang, B. J., Golledge, C. L., & Riley, T. V. (2007) · Internal Medicine Journal · doi:10.1111/j.1445-5994.2007.01403.x · Cited by 112
Fulminant Clostridium difficile colitis
Adams, S. D., & Mercer, D. (2007) · Current Opinion in Critical Care · doi:10.1097/mcc.0b013e3282638879 · Cited by 109
Clostridium difficile infection: molecular pathogenesis and novel therapeutics
Rineh, A., Kelso, M. J., Vatansever, F., Tegos, G. P., & Hamblin, M. R. (2014) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2014.866515 · Cited by 120
Glucocorticoids Are Associated With Increased Risk of Short-Term Mortality in Hospitalized Patients With Clostridium difficile -Associated Disease
Das, R. K., Feuerstadt, P., & Brandt, L. J. (2010) · The American Journal of Gastroenterology · doi:10.1038/ajg.2010.142 · Cited by 101
Probiotics for the prevention of antibiotic-associated diarrhea and Clostridium difficile infection among hospitalized patients: systematic review and meta-analysis.
Pattani, R., Palda, V. A., Hwang, S. W., & Shah, P. S. (2013) · Europe PMC (PubMed Central) · Cited by 97
Clostridium difficile infection in solid organ transplant recipients
Riddle, D. J., & Dubberke, E. R. (2008) · Current Opinion in Organ Transplantation · doi:10.1097/mot.0b013e3283186b51 · Cited by 93
Clostridium difficile Infection in the Intensive Care Unit
Riddle, D. J., & Dubberke, E. R. (2009) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2009.04.011 · Cited by 91
Clostridium difficile infection in horses: A review
Diab, S. S., Songer, G., & Uzal, F. A. (2013) · Veterinary Microbiology · doi:10.1016/j.vetmic.2013.03.032 · Cited by 90
Open flap debridement of peri‐implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial
Hallström, H., Persson, G. R., Lindgren, S., & Renvert, S. (2017) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.12805 · Cited by 88
Early Surgical Intervention for Fulminant Pseudomembranous Colitis
Ali, S. O., Welch, J. P., & Dring, R. (2008) · The American Surgeon · doi:10.1177/000313480807400105 · Cited by 84
Is Lactobacillus rhamnosus GG Effective in Preventing the Onset of Antibiotic-Associated Diarrhoea: A Systematic Review
Hawrelak, J. A., Whitten, D. L., & Myers, S. P. (2005) · Digestion · doi:10.1159/000087637 · Cited by 84
Microarray Identification of Clostridium difficile Core Components and Divergent Regions Associated with Host Origin
Janvilisri, T., Scaria, J., Thompson, A. D., Nicholson, A. C., Limbago, B. M., Arroyo, L. G., Songer, J. G., Grohn, Y. T., & Chang, Y. (2009) · Journal of Bacteriology · doi:10.1128/jb.00222-09 · Cited by 83
Clostridium difficilein foods and animals: history and measures to reduce exposure
Rodriguez‐Palacios, A., Borgmann, S., Kline, T. R., & LeJeune, J. T. (2013) · Animal Health Research Reviews · doi:10.1017/s1466252312000229 · Cited by 87
Inhibition of Clostridium difficile growth and adhesion to enterocytes by Bifidobacterium supernatants
Trejo, F. M., Minnaard, J., Pérez, P. F., & Antoni, G. L. D. (2006) · Anaerobe · doi:10.1016/j.anaerobe.2006.03.004 · Cited by 76
Absence of pseudomembranes inClostridium difficile-associated diarrhea in patients using immunosuppression agents
Nomura, K., Fujimoto, Y., Yamashita, M., Morimoto, Y., Ohshiro, M., Sato, K., Oyake, T., Kowata, S., Konishi, H., Yoshikawa, T., et al. (2008) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520802321238 · Cited by 73
Pathogenesis and treatment of Clostridium difficile infection
Tonna, I., & Welsby, P. D. (2005) · Postgraduate Medical Journal · doi:10.1136/pgmj.2004.028480 · Cited by 71
Clinical manifestations, treatment and control of infections caused by Clostridium difficile
Bouza, E., Muñóz, P., & Alonso, R. (2005) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2005.01165.x · Cited by 68
The Distribution and Density of Clostridium difficile Toxin Receptors on the Intestinal Mucosa of Neonatal Pigs
Keel, M. K., & Songer, J. G. (2007) · Veterinary Pathology · doi:10.1354/vp.44-6-814 · Cited by 67
Iatrogenic pathology of the intestines
McCarthy, A. J., Lauwers, G. Y., & Sheahan, K. D. (2015) · Histopathology · doi:10.1111/his.12598 · Cited by 66
Dramatic reduction in Clostridium difficile ribotype 027-associated mortality with early fecal transplantation by the nasogastric route: a preliminary report
Lagier, J., Delord, M., Million, M., Parola, P., Stein, A., Brouqui, P., & Raoult, D. (2015) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-015-2394-x · Cited by 66
Probiotics for antibiotic-associated diarrhea: Do we have a verdict?
Issa, I. A., & Moucari, R. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i47.17788 · Cited by 65
Redefining Lactose as a Conditional Prebiotic
Szilagyi, A. (2004) · Canadian Journal of Gastroenterology · doi:10.1155/2004/350732 · Cited by 63
Clostridium difficile
Badger, V. O., Ledeboer, N., Graham, M. B., & Edmiston, C. E. (2012) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607112446703 · Cited by 61
Severity of Clostridium difficile‐associated diarrhea in solid organ transplant patients
Gellad, Z. F., Alexander, B. D., Liu, J. K., Griffith, B. C., Meyer, A. M. J., Johnson, J., & Muir, A. J. (2007) · Transplant Infectious Disease · doi:10.1111/j.1399-3062.2007.00255.x · Cited by 61
Biopsy interpretation of colonic biopsies when inflammatory bowel disease is excluded
Khor, T. S., Fujita, H., Nagata, K., Shimizu, M., & Lauwers, G. Y. (2012) · Journal of Gastroenterology · doi:10.1007/s00535-012-0539-6 · Cited by 58
Colitis Due toClostridium DifficileToxins: Underdiagnosed, Highly Virulent, and Nosocomial
Fordtran, J. S. (2006) · Baylor University Medical Center Proceedings · doi:10.1080/08998280.2006.11928114 · Cited by 56
Clostridium perfringens type C and Clostridium difficile co-infection in foals
Uzal, F. A., Diab, S. S., Blanchard, P. C., Moore, J. D., Anthenill, L. A., Shahriar, F., García, J. P., & Songer, J. G. (2011) · Veterinary Microbiology · doi:10.1016/j.vetmic.2011.11.023 · Cited by 52
Calprotectin and Lactoferrin Faecal Levels in Patients with Clostridium difficile Infection (CDI): A Prospective Cohort Study
Swale, A., Miyajima, F., Roberts, P., Hall, A. J., Little, M., Beadsworth, M., Beeching, N. J., Kolamunnage‐Dona, R., Parry, C. M., & Pirmohamed, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106118 · Cited by 52
Germination of spores of Clostridium difficile strains, including isolates from a hospital outbreak of Clostridium difficile-associated disease (CDAD)
Paredes‐Sabja, D., Bond, C., Carman, R. J., Setlow, P., & Sarker, M. R. (2008) · Microbiology · doi:10.1099/mic.0.2008/016592-0 · Cited by 52
Avoiding Colectomy during Surgical Management of Fulminant Clostridium difficile Colitis
Olivas, A. D., Umanskiy, K., Zuckerbraun, B. S., & Alverdy, J. C. (2010) · Surgical Infections · doi:10.1089/sur.2010.026 · Cited by 49
Past, Present, and Future Therapies for Clostridium difficile–Associated Disease
McCoy, D., Kuyumjian, A., Wynd, M. A., & Cicogna, C. E. (2006) · Annals of Pharmacotherapy · doi:10.1345/aph.1h332 · Cited by 46
Clostridium difficile Infection in Production Animals and Avian Species: A Review
Moono, P., Foster, N. F., Hampson, D. J., Knight, D. R., Bloomfield, L., & Riley, T. V. (2016) · Foodborne Pathogens and Disease · doi:10.1089/fpd.2016.2181 · Cited by 49
Diagnostic role of stool culture & toxin detection in antibiotic associated diarrhoea due to Clostridium difficile in children.
Gogate, A., De, A., Nanivadekar, R., Mathur, M., Saraswathi, K., Jog, A. S., & Kulkarni, M. (2005) · PubMed · Cited by 43
Clostridium difficile infection
Stanley, J. D., Bartlett, J. G., Dart, B. W., & Ashcraft, J. (2013) · Current Problems in Surgery · doi:10.1067/j.cpsurg.2013.02.004 · Cited by 42
Defined Nutrient Diets Alter Susceptibility to Clostridium difficile Associated Disease in a Murine Model
Moore, J. H., Pinheiro, C. C. D., Zaenker, E. I., Bolick, D. T., Kolling, G. L., van Opstal, E. J., Noronha, F. J., de Medeiros, P. H. Q. S., Rodriguez, R. S., Lima, A. Â. M., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0131829 · Cited by 40
Risk Factors for the Development ofClostridium difficile-associated Colitis after Colorectal Cancer Surgery
Yeom, C. H., Cho, M. M., Baek, S. K., & Bae, O. S. (2010) · Journal of the Korean Society of Coloproctology · doi:10.3393/jksc.2010.26.5.329 · Cited by 42
The burden of Clostridium difficile-associated disease following digestive tract surgery in Japan
Yasunaga, H., Horiguchi, H., Hashimoto, H., Matsuda, S., & Fushimi, K. (2012) · Journal of Hospital Infection · doi:10.1016/j.jhin.2012.07.023 · Cited by 41
Low Risk of Irritable Bowel Syndrome afterClostridium difficileInfection
Piche, T., Vanbiervliet, G., Girard-Pipau, F., Dainese, R., Hébuterne, X., Rampal, P., & Collins, S. M. (2007) · Canadian Journal of Gastroenterology · doi:10.1155/2007/262478 · Cited by 40
Germination of spores of Clostridium difficile strains, including isolates from a hospital outbreak of Clostridium difficile-associated disease (CDAD)
Paredes‐Sabja, D., Bond, C., Carman, R. J., Setlow, P., & Sarker, M. R. (2009) · Microbiology · doi:10.1099/mic.0.30214-0 · Cited by 39
Antibiotic-associated diarrhoea
Coté, G. A., & Buchman, A. L. (2006) · Expert Opinion on Drug Safety · doi:10.1517/14740338.5.3.361 · Cited by 37
Antimicrobial Therapy of Clostridium difficile-Associated Diarrhea
Bouza, E., Burillo, A., & Muñóz, P. (2006) · Medical Clinics of North America · doi:10.1016/j.mcna.2006.07.011 · Cited by 36
Long-Term Changes in Human Colonic Bifidobacterium Populations Induced by a 5-Day Oral Amoxicillin-Clavulanic Acid Treatment
Mangin, I., Lévêque, C., Magne, F., Suau, A., & Pochart, P. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050257 · Cited by 36
Clostridium difficile–associated infection: a disease of varying severity
Jawa, R. S., & Mercer, D. (2012) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2012.05.025 · Cited by 33
Clostridium difficile Colitis
Efron, P. A., & Mazuski, J. E. (2009) · Surgical Clinics of North America · doi:10.1016/j.suc.2008.09.014 · Cited by 32
An Unusual Presentation of Pseudomembranous Colitis
Jabbar, S. A., Sundaramurthi, S., Elamurugan, T., Goneppanavar, M., & Ramakrishnaiah, V. P. N. (2019) · Cureus · doi:10.7759/cureus.4570 · Cited by 31
The role of surgery in Clostridium difficile colitis
Noblett, S. E., Welfare, M., & Seymour, K. (2009) · BMJ · doi:10.1136/bmj.b1563 · Cited by 31
Germination response of spores of the pathogenic bacterium Clostridium perfringens and Clostridium difficile to cultured human epithelial cells
Paredes‐Sabja, D., & Sarker, M. R. (2011) · Anaerobe · doi:10.1016/j.anaerobe.2011.02.001 · Cited by 30
Prevalence and clinical features of Clostridium difficile-associated diarrhea in a tertiary hospital in northern Taiwan.
Hsu, M.-S., Wang, J. T., Huang, W. K., Liu, Y.-C., & Chang, S. (2006) · PubMed · Cited by 30
Risk factors and mortality associated with Clostridium difficile-associated diarrhoea at a VA hospital
Changela, U., Cannon, J. P., Aneziokoro, C., Shah, P. S., Thottapurathu, L., & Lentino, J. R. (2004) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2004.07.011 · Cited by 30
Racial Differences in Clostridium difficile Infection Rates Are Attributable to Disparities in Health Care Access
Mao, E. J., Kelly, C. R., & Machan, J. T. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00795-15 · Cited by 29
Persistence of Clostridium difficile RT 237 infection in a Western Australian piggery
Moono, P., Putsathit, P., Knight, D. R., Squire, M. M., Hampson, D. J., Foster, N. F., & Riley, T. V. (2015) · Anaerobe · doi:10.1016/j.anaerobe.2015.11.012 · Cited by 29
Severe Clostridium difficile infections in intensive care units: Diverse clinical presentations
Lee, J., Hung, Y., Tsai, B., Tsai, P.-J., & Ko, W. (2020) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2020.07.012 · Cited by 26
Recommendations for the diagnosis and treatment of Clostridioides difficile infection: An official clinical practice guideline of the Spanish Society of Chemotherapy (SEQ), Spaish Society of Internal Medicine (SEMI) and the working group of Postoperative Infection of the Spanish Society of Anesthesia and Reanimation (SEDAR)
Infecciosas, I. D. I. S. G. M. S. D. M. C. Y. E., Bouza, E., Aguado, J. M., Alcalá, L., Almirante, B., Alonso‐Fernández, P., Borges-Sa, M., Cobo, J., Guardiola, J., Horcajada, J. P., et al. (2020) · Revista Española de Quimioterapia · doi:10.37201/req/2065.2020 · Cited by 26
Clostridium difficile Infection in the Intensive Care Unit
Leclair, M.-A., Allard, C., Lesur, O., & Pépin, J. (2009) · Journal of Intensive Care Medicine · doi:10.1177/0885066609350871 · Cited by 24
Outcomes of emergency colectomy for fulminant Clostridium difficile colitis
Al-Abed, Y. A., Gray, E., & Rothnie, N. D. (2010) · The Surgeon · doi:10.1016/j.surge.2010.06.003 · Cited by 25
A rat model of mild intestinal inflammation induced byStaphylococcus aureusenterotoxin B
Pérez‐Bosque, A., & Moretó, M. (2010) · Proceedings of The Nutrition Society · doi:10.1017/s0029665110001849 · Cited by 25
Outcomes of Patients Who Develop Symptomatic Clostridium difficile Infection After Solid Organ Transplantation
Mitu-Pretorian, O.-M., Forgacs, B., Qumruddin, A., Tavakoli, A., Augustine, T., & Pararajasingam, R. (2010) · Transplantation Proceedings · doi:10.1016/j.transproceed.2010.04.057 · Cited by 23
Antibiotic and Modulation of Microbiota
Rizzatti, G., Ianiro, G., & Gasbarrini, A. (2018) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000001069 · Cited by 24
Fulminant Clostridioides difficile Infection: A Review of Treatment Options for a Life-Threatening Infection
Carlson, T. J., Gonzales-Luna, A. J., & Garey, K. W. (2022) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0041-1740973 · Cited by 23
Nutrition and Diarrheal Disease and Enteric Pathogens
Siddiqui, F. J., Belayneh, G., & Bhutta, Z. A. (2020) · Springer eBooks · doi:10.1007/978-3-030-56913-6_8 · Cited by 23
Vomiting, Diarrhea, Constipation, and Gastroenteritis
Getto, L. P., Zeserson, E., & Breyer, M. J. (2011) · Emergency Medicine Clinics of North America · doi:10.1016/j.emc.2011.01.005 · Cited by 23
Clostridium difficile infection
Hernández, L. A., Ramírez, E. R., & Santiago, E. B. (2017) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2017.04.034 · Cited by 22
Clostridioides difficile Infection in the Stem Cell Transplant and Hematologic Malignancy Population
Misch, E. A., & Safdar, N. (2019) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2019.02.010 · Cited by 22
Clinical approach to severe Clostridium difficile infection: Update for the hospital practitioner
Pant, C., Sferra, T. J., Deshpande, A., & Minocha, A. (2011) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2011.04.009 · Cited by 21
Review of medical and surgical management of Clostridium difficile infection
Faris, B., Blackmore, A., & Haboubi, N. Y. (2010) · Techniques in Coloproctology · doi:10.1007/s10151-010-0574-3 · Cited by 21
Gastric epithelial anti-microbial peptides—histological correlation and influence of anatomical site and peptic ulcer disease
Taha, A. S., Faccenda, E., Angerson, W. J., Balsitis, M., & KELLY, R. W. (2004) · Digestive and Liver Disease · doi:10.1016/j.dld.2004.07.019 · Cited by 21
Clostridium difficilecausing acute renal failure: Case presentation and review
Arrich, J. (2005) · World Journal of Gastroenterology · doi:10.3748/wjg.v11.i8.1245 · Cited by 21
Efficacy assessment of two antibiotic prophylaxis regimens in oral and maxillofacial trauma surgery: preliminary results.
Campos, G. B. P., Lucena, E. E. D. S., da Silva, J. S. P., Gomes, P. P., & Germano, A. R. (2015) · PubMed Central · Cited by 20
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Authors: Hurley, B. W., & Nguyen, C. C.
Affiliations: Mayo Clinic in Arizona (US)
ORCID: Nguyen, Cuong C.
Venue: Archives of Internal Medicine
Publisher: American Medical Association (AMA)
Published: 2002-10-28
Volume: 162
Issue: 19
Pages: 2177
ISSN: 0003-9926 (ISSN-L)
DOI: 10.1001/archinte.162.19.2177
OpenAlex: W2120700667
Cited by: 288
References: 32
Citations by year: 2026: 4 · 2025: 5 · 2024: 1 · 2023: 1 · 2022: 6 · 2021: 10 · 2020: 64 · 2019: 8 · 2018: 5 · 2017: 12 · 2016: 4 · 2015: 12 · 2014: 10 · 2013: 9 · 2012: 12
FWCI: 5.08
Type: journal article
Language: en
Open access: closed
Locations: Archives of Internal Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Infectious Diseases › Clostridium difficile and Clostridium perfringens research
Health Sciences › Medicine › Gastroenterology › Microscopic Colitis
Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
Keywords: pseudomembranous colitis, Clostridium difficile infection, antibiotic-associated diarrhea, vancomycin, metronidazole, asymptomatic carriage, fulminant colitis, colectomy, infection control, antibiotic stewardship
MeSH terms: Anti-Bacterial Agents, Clostridium Infections, Diarrhea, Enterocolitis, Pseudomembranous, Humans, Recurrence, Clostridioides difficile

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The Spectrum of Pseudomembranous Enterocolitis and Antibiotic-Associated Diarrhea

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