Cited by 52Bone health and osteoporosis researchOpioid Use Disorder TreatmentPain Management and Opioid Use

Opioid osteoporosis

Daniell, Harry W.·2004·Archives of Internal Medicine

Integrity signals

Registry

Crossref · 10.1001/archinte.164.3.338-a

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  • Among fentanyl-exposed patients, LAIB was superior to TMB for urine samples negative for fentanyl.

    “Both buprenorphine treatments were effective in reducing opioid withdrawal and cravings, but LAIB was superior to TMB for urine samples negative for fentanyl among patients who were fentanyl-exposed.12”
  • Direct comparisons showing comparable outcomes for long-acting injectable buprenorphine relative to TMB suggest that LAIB may be a viable alternative for patients at high risk of oral health problems, including fentanyl-exposed patients who may need higher sublingual doses.

    “Direct comparisons showing comparable outcomes for long-acting injectable buprenorphine (LAIB) relative to TMB suggest LAIB may be a viable treatment alternative for patients at high risk for oral health problems, including patients exposed to fentanyl who may require higher sublingual doses.”
  • Both LAIB and TMB were effective in reducing opioid withdrawal and cravings.

    “Both buprenorphine treatments were effective in reducing opioid withdrawal and cravings, but LAIB was superior to TMB for urine samples negative for fentanyl among patients who were fentanyl-exposed.12”
  • Post hoc comparisons from a randomized controlled trial comparing LAIB with TMB showed notable but underpowered group differences favoring LAIB for urine samples negative for any opioid.

    “Post hoc comparisons from a randomized controlled trial comparing LAIB to TMB showed notable, but underpowered, group differences favoring the former for urine samples negative for any opioid.”
  • Testosterone therapy may be justifiable in men receiving opioids who may suffer from opioid-induced suppression of testosterone levels and associated sexual dysfunction, osteoporosis, and/or muscle atrophy.

    “Testosterone therapy may be justifiable in patients with some of these conditions, such as men receiving opioids, who may suffer from opioid-induced suppression of testosterone levels 32 and sexual dysfunction, 33 osteoporosis, and/or muscle atrophy.34”

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Authors
Daniell, H. W.
Venue
Archives of Internal Medicine
Published
2004-02-09
Volume
164
Issue
3
Pages
338
ISSN
0003-9926 (ISSN-L)
OpenAlex
W2811380478
Cited by
52
References
0
Citations by year
2025: 3 · 2024: 2 · 2023: 1 · 2021: 2 · 2020: 1 · 2019: 5 · 2018: 3 · 2017: 5 · 2016: 2 · 2015: 4 · 2014: 4 · 2013: 6 · 2012: 1
FWCI
1.63
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Internal Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords
opioid analgesics, osteoporosis, bone loss, bone mineral density, drug-induced bone disease
MeSH terms
Analgesics, Opioid, Dose-Response Relationship, Drug, Female, Humans, Hypogonadism, Male, Opioid-Related Disorders, Osteoporosis, Bone Density, Muscle, Skeletal, Fractures, Bone

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