The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Clinical Symptoms and Length of Survival in Patients With Terminal Cancer
Abstract
Planning terminal care for patients with malignant neoplasms is difficult, in part, because accurate measures of prognosis have not been defined. Using data from the National Hospice Study, we examined the correlation of 14 easily assessable clinical symptoms with survival in patients with terminal cancer. Performance status was the most important clinical factor in estimating survival time, but five other symptoms had independent predictive value as well (shortness of breath, problems eating or anorexia, trouble swallowing, dry mouth, and weight loss). We generated four parametric accelerated time survival models to estimate survival in patients with combinations of these symptoms and validated the log-normal model on the entire data set. This model was unaffected by patient age, sex, primary tumor type, or site. Our findings illustrate the value of biologically "soft" clinical data in predicting survival in patients with terminal cancer. The prevalence of similar symptoms among patients with cancer of various primary and metastatic sites also supports the concept of a common final clinical pathway in patients with advanced malignant neoplasms.
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Cites
Clinical Prediction Rules: Applications and Methodological Standards
Wasson, J. H., Sox, H. C., Neff, R. K., & Goldman, L. (1985) · New England Journal of Medicine · doi:10.1056/nejm198509263131306 · Cited by 1,357
Cited by
Prevalence of pain in patients with cancer: a systematic review of the past 40 years
van den Beuken-van Everdingen, M. H. J., de Rijke, J. M., Kessels, A. G., Schouten, H. C., van Kleef, M., & Patijn, J. (2007) · Annals of Oncology · doi:10.1093/annonc/mdm056 · Cited by 1,923
Solano, J. P., Gomes, B., & Higginson, I. J. (2006) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2005.06.007 · Cited by 1,191
Symptom Prevalence in Patients with Incurable Cancer: A Systematic Review
Teunissen, S. C. C. M., Wesker, W., Kruitwagen, C., de Haes, H. C. J. M., Voest, E. E., & de Graeff, A. (2007) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2006.10.015 · Cited by 990
Meuser, T., Pietruck, C., Radbruch, L., Stute, P., Lehmann, K. A., & Grond, S. (2001) · Pain · doi:10.1016/s0304-3959(01)00324-4 · Cited by 560
Prevalence of symptoms among patients with advanced cancer: An international collaborative study
Vainio, A., & Auvinen, A. (1996) · Journal of Pain and Symptom Management · doi:10.1016/0885-3924(96)00042-5 · Cited by 455
Metadata
- Authors
- Reuben, D. B.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1988-07-01
- Volume
- 148
- Issue
- 7
- Pages
- 1586
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2087820563
- Cited by
- 327
- References
- 1
- FWCI
- 6.64
- Type
- journal article
- Language
- en
- Open access
- closed
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- Reuben, D. B. (1988). Clinical Symptoms and Length of Survival in Patients With Terminal Cancer. Archives of Internal Medicine. https://doi.org/10.1001/archinte.1988.00380070082020
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
