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Cited by 1,191Palliative Care and End-of-Life IssuesPalliative and Oncologic CarePain Management and Opioid Use

A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease

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Solano, Joao Paulo, Gomes, Barbara, Higginson, Irene J.·2006·Journal of Pain and Symptom Management
DOI 10.1016/j.jpainsymman.2005.06.007
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Abstract

Little attention has been paid to the symptom management needs of patients with life-threatening diseases other than cancer. In this study, we aimed to determine to what extent patients with progressive chronic diseases have similar symptom profiles. A systematic search of medical databases (MEDLINE, EMBASE, and PsycINFO) and textbooks identified 64 original studies reporting the prevalence of 11 common symptoms among end-stage patients with cancer, acquired immunodeficiency syndrome (AIDS), heart disease, chronic obstructive pulmonary disease, or renal disease. Analyzing the data in a comparative table (a grid), we found that the prevalence of the 11 symptoms was often widely but homogeneously spread across the five diseases. Three symptoms-pain, breathlessness, and fatigue-were found among more than 50% of patients, for all five diseases. There appears to be a common pathway toward death for malignant and nonmalignant diseases. The designs of symptom prevalence studies need to be improved because of methodological disparities in symptom assessment and designs.

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  • The symptom burden for CHF patients has been likened to those with advanced cancer or acquired immune deficiency syndrome.

    “The symptom burden for CHF patients has been likened to those with advanced cancer or acquired immune deficiency syndrome, 6 , 12”

    From Prioritizing symptom management in the treatment of chronic heart failure (2020) · cites this paper as [12]

  • Prevalence of anxiety and depression in COPD is generally higher than that reported in some other advanced chronic diseases.

    “Estimates of prevalence of anxiety and depression in COPD vary widely but are generally higher than those reported in some other advanced chronic diseases.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [32]

  • In a systematic review of 64 studies focused on patients with severe disease, the prevalence of depression ranged from 37 to 71%.

    “In a systematic review32 of 64 studies that focused on patients with severe disease, the prevalence of depression ranged from 37 to 71%, and that of anxiety from 50 to 75%”

    From Anxiety and Depression in COPD (2008) · cites this paper as [32]

  • The prevalence of depression and anxiety in severe COPD is comparable to or higher than prevalence rates in other advanced diseases such as cancer, AIDS, heart disease, and renal disease.

    “figures comparable to or higher than prevalence rates in other advanced diseases such as cancer, AIDS, heart disease, and renal disease.”

    From Anxiety and Depression in COPD (2008) · cites this paper as [32]

  • In a systematic review of 64 studies focused on patients with severe disease, the prevalence of anxiety ranged from 50 to 75%.

    “In a systematic review32 of 64 studies that focused on patients with severe disease, the prevalence of depression ranged from 37 to 71%, and that of anxiety from 50 to 75%”

    From Anxiety and Depression in COPD (2008) · cites this paper as [32]

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Cites

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1 of the 126 references couldn’t be matched to a known paper.

Research works printed but not linked: 8

  1. Hinton J. The physical and mental stress of dying. Q J Med 1963;32:1--21.
  2. Breitbart W, Jaramillo JR, Chochinov HMC. Palliative and terminal care. In: Holland JC, ed. Psycho-oncology. New York: Oxford University Press, 1998: 437--449.
  3. Gibbs JSR. Heart disease. In: Addington-Hall J, Higginson IJ, eds. Palliative care for non-cancer patients. New York: Oxford University Press, 2001: 30--43.
  4. Wuerth D, Finkelstein SH, Kliger AS, Finkelstein FO. Chronic peritoneal dialysis patients diagnosed with clinical depression: results of phar- macologic therapy. Semin Dial 2003;16(6):424--427.
  5. Breitbart W, Chochinov H, Passik S. Psychiatric symptoms in palliative medicine. In: Derek D, Hanks G, Cherny N, Calman K, eds. Oxford text- book of palliative medicine. New York: Oxford Uni- versity Press, 2004: 746--771.
  6. Doyle D, Hanks GWC, MacDonald M, eds Oxford textbook of palliative medi- cine. Oxford: Oxford University Press, 1998.
  7. Hoskin P, Makin W, eds. Oncology for pallia- tive medicine. New York: Oxford University Press, 1998.
  8. Levy J, Morgan J, Brown E. Oxford handbook of dialysis. New York: Oxford University Press, 2001.

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Authors
Solano, J. P., Gomes, B., & Higginson, I. J.
Affiliations
King's College London (GB)
Corresponding author
Higginson, Irene J.
ORCID
Higginson, Irene J.
Venue
Journal of Pain and Symptom Management
Publisher
Elsevier BV
Published
2006-01
Volume
31
Issue
1
Pages
58-69
ISSN
0885-3924 (ISSN-L)
DOI
10.1016/j.jpainsymman.2005.06.007
OpenAlex
W2144048086
Cited by
1,191
References
126
Citations by year
2026: 26 · 2025: 49 · 2024: 52 · 2023: 52 · 2022: 51 · 2021: 67 · 2020: 79 · 2019: 67 · 2018: 72 · 2017: 84 · 2016: 75 · 2015: 77 · 2014: 65 · 2013: 60 · 2012: 74
FWCI
39.35
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Pain and Symptom Management (publishedVersion)
  • PubMed (publishedVersion)
  • Research Portal (King's College London) (submittedVersion)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords
symptom prevalence, symptom management, cancer, AIDS, heart disease, chronic obstructive pulmonary disease, kidney disease, pain, dyspnea, fatigue, symptom assessment
MeSH terms
Acquired Immunodeficiency Syndrome, Aged, Aged, 80 and over, Depression, Female, Heart Diseases, Humans, Kidney Diseases, Male, Middle Aged, Neoplasms, Palliative Care, Pulmonary Disease, Chronic Obstructive

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