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Primary Care Clinicians' Experiences With Treatment Decision Making for Older Persons With Multiple Conditions
Open accessAbstract
BACKGROUND: Clinicians are caring for an increasing number of older patients with multiple diseases in the face of uncertainty concerning the benefits and harms associated with guideline-directed interventions. Understanding how primary care clinicians approach treatment decision making for these patients is critical to the design of interventions to improve the decision-making process. METHODS: Focus groups were conducted with 40 primary care clinicians (physicians, nurse practitioners, and physician assistants) in academic, community, and Veterans Affairs-affiliated primary care practices. Participants were given open-ended questions about their approach to treatment decision making for older persons with multiple medical conditions. Responses were organized into themes using qualitative content analysis. RESULTS: The participants were concerned about their patients' ability to adhere to complex regimens derived from guideline-directed care. There was variability in beliefs regarding, and approaches to balancing, the benefits and harms of guideline-directed care. There was also variability regarding how the participants involved patients in the process of decision making, with clinicians describing conflicts between their own and their patients' goals. The participants listed a number of barriers to making good treatment decisions, including the lack of outcome data, the role of specialists, patient and family expectations, and insufficient time and reimbursement. CONCLUSIONS: The experiences of practicing clinicians suggest that they struggle with the uncertainties of applying disease-specific guidelines to their older patients with multiple conditions. To improve decision making, they need more data, alternative guidelines, approaches to reconciling their own and their patients' priorities, the support of their subspecialist colleagues, and an altered reimbursement system.
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“Fried et al. showed that clinicians struggle with the uncertainties of applying disease-specific guidelines to their patients with multiple conditions, and would therefore benefit from a number of tools to assist them in decision making for this population [12].”
From ESPEN guideline on nutritional support for polymorbid medical inpatients (2023) · cites this paper as [12]
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Boyd, C. M., Darer, J., Boult, C., Fried, L. P., Boult, L., & Wu, A. W. (2005) · JAMA · doi:10.1001/jama.294.6.716 · Cited by 2,581 · cited 1×
“Second, the presence of these conditions may also increase the likelihood that the individual will experience adverse effects with any given intervention.(3,4) Finally, the polypharmacy that generally accompanies multimorbidity confers an increased risk of adverse drug events, independent of the chronic conditions.”
BackgroundUnderstanding the treatment preferences of seriously ill patients.
Fried, T., Bradley, E. H., Towle, V., & Allore, H. (2002) · New England Journal of Medicine · doi:10.1056/nejmsa012528 · Cited by 1,426
Self-citationEffectiveness of strategies for informing, educating, and involving patients
Coulter, A., & Ellins, J. (2007) · BMJ · doi:10.1136/bmj.39246.581169.80 · Cited by 1,128
Potential pitfalls of disease-specific guidelines for patients with multiple conditions.
Tinetti, M., Bogardus, S., & Agostini, J. V. (2004) · New England Journal of Medicine · doi:10.1056/nejmsb042458 · Cited by 969 · cited 1×
“Second, the presence of these conditions may also increase the likelihood that the individual will experience adverse effects with any given intervention.(3,4) Finally, the polypharmacy that generally accompanies multimorbidity confers an increased risk of adverse drug events, independent of the chronic conditions.”
BackgroundSelf-citationPolypharmacy and Prescribing Quality in Older People
Steinman, M. A., Landefeld, C., Rosenthal, G. E., Berthenthal, D., Sen, Ś., & Kaboli, P. (2006) · Journal of The American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00889.x · Cited by 580
Incidence of intracranial hemorrhage in patients with atrial fibrillation who are prone to fall
Gage, B. F., Birman-Deych, E., Kerzner, R., Radford, M. J., Nilasena, D. S., & Rich, M. W. (2005) · The American Journal of Medicine · doi:10.1016/j.amjmed.2005.02.022 · Cited by 322 · cited 1×
“In addition to the studies demonstrating the risk of adverse outcomes associated with guideline-directed care, evidence also suggests that the patients who are at the highest risk for these adverse outcomes may also be the ones most likely to derive benefit from the intervention.(17) Clinicians’ descriptions of how th…”
BackgroundRisk Factors for Adverse Drug Events Among Older Adults in the Ambulatory Setting
Field, T., Gurwitz, J., Harrold, L., Rothschild, J., Debellis, K., Seger, A., Auger, J. C., Garber, L., Cadoret, C. A., Fish, L., et al. (2004) · Journal of The American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52367.x · Cited by 315 · cited 1×
“Finally, the polypharmacy that generally accompanies multimorbidity confers an increased risk of adverse drug events, independent of the chronic conditions.(5,6) On the other hand, editorials and clinical studies remind readers that the clinical trials”
BackgroundViews of older adults on patient participation in medication-related decision making
Belcher, V. N., Fried, T., Agostini, J. V., & Tinetti, M. (2006) · Journal of general internal medicine · doi:10.1111/j.1525-1497.2006.00329.x · Cited by 279 · cited 1×
“Moreover, other clinicians noted that the reduction in risk for a disease-specific outcome might not be what was most important to the patient, an observation supported by studies indicating that the adverse effects of medications may be as, if not more, important to patients than their primary effects.(20,21) Disagre…”
ResultSelf-citationViews of Older Persons with Multiple Morbidities on Competing Outcomes and Clinical Decision‐Making
Fried, T. R., McGraw, S., Agostini, J. V., & Tinetti, M. E. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.01923.x · Cited by 203 · cited 1×
“Moreover, other clinicians noted that the reduction in risk for a disease-specific outcome might not be what was most important to the patient, an observation supported by studies indicating that the adverse effects of medications may be as, if not more, important to patients than their primary effects.(20,21) Disagre…”
ResultSelf-citationPitfalls of Converting Practice Guidelines Into Quality Measures
Walter, L. C., Davidowitz, N. P., Heineken, P. A., & Covinsky, K. E. (2004) · JAMA · doi:10.1001/jama.291.20.2466 · Cited by 197
Research works printed but not linked: 1
- [13]Rosenfeld KE Wenger NS Kagawa-Singer M End-of-life decision making: a qualitative study of elderly individuals J Gen Intern Med 2000 15 9 620 5 11029675 PMC1495587
Cited by
Sorted by citations
Items 101–200 of 225
Reeves, D., Hann, M., Rick, J., Rowe, K., Small, N., Burt, J., Roland, M. O., Protheroe, J., Blakeman, T., Richardson, G. A., et al. (2014) · British Journal of General Practice · doi:10.3399/bjgp14x681385 · Cited by 31
Beverly, E. A., Wray, L. A., Chiu, C., & LaCoe, C. L. (2014) · Clinical Diabetes · doi:10.2337/diaclin.32.1.12 · Cited by 25
van Summeren, J., Haaijer-Ruskamp, F., & Schuling, J. (2016) · Journal of The American Geriatrics Society · doi:10.1111/jgs.14415 · Cited by 27
Shared decision making between older people with multimorbidity and GPs: a qualitative study
Brown, E., Poltawski, L., Pitchforth, E., Richards, S., Campbell, J., & Butterworth, J. (2022) · The British journal of general practice : the journal of the Royal College of General Practitioners · doi:10.3399/bjgp.2021.0529 · Cited by 25
Schuttner, L., Sherlock, S. H., Simons, C. E., Ralston, J. D., Rosland, A.-M. M., Nelson, K. M., Lee, J. R., & Sayre, G. G. (2022) · BMC Family Practice · doi:10.1186/s12875-022-01633-x · Cited by 25
“stakeholders, including between more organ or diseasespecific specialists and “holistic” PCPs, [21] and between patients prioritizing symptoms and clinicians focusing on long-term prognosis [38, 39].”
BackgroundReconsidering evidence-based practice in prosthetic rehabilitation: a shared enterprise
van Twillert, S., Geertzen, J., Hemminga, T., Postema, K., & Lettinga, A. (2013) · Prosthetics and orthotics international · doi:10.1177/0309364612459541 · Cited by 25
Visvanathan, A., Mead, G., Dennis, M., Whiteley, W., Doubal, F., & Lawton, J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222500 · Cited by 24
Ngangue, P., Forgues, C., Nguyen, T. N., Sasseville, M., Gallagher, F., Loignon, C., Stewart, M., Brown, J. B., Chouinard, M., & Fortin, M. (2020) · Health Expectations · doi:10.1111/hex.13035 · Cited by 35
Slightam, C., Brandt, K., Jenchura, E. C., Lewis, E. T., Asch, S., & Zulman, D. M. (2018) · Chronic Illness · doi:10.1177/1742395317699448 · Cited by 23
“Patients’ values influence their health behaviors,(35) so when those values form the basis of a care plan, patients are more likely to follow through with the necessary self-management behaviors.(36,37) In addition, addressing a condition that is causing a patient discomfort, frustration, or burden may remove barriers…”
Backgroundvan Peet, P. V., Drewes, Y., Gussekloo, J., & de Ruijter, W. (2015) · The British journal of general practice : the journal of the Royal College of General Practitioners · doi:10.3399/bjgp15x687373 · Cited by 23
Multimorbidity and Quality of Preventive Care in Swiss University Primary Care Cohorts
Streit, S., da Costa, B. R., Bauer, D. C., Collet, T., Weiler, S., Zimmerli, L., Frey, P., Cornuz, J., Gaspoz, J., Battegay, E. J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096142 · Cited by 23
“The increasing number of diseases with aging [2,3], the adverse effects of polypharmacy [13], the time constraints of medical visits [2] and the effects of comorbidities on patients’ ability to manage their self-care [9] all seem to reduce the likelihood of high quality care among those with multimorbidity.”
BackgroundRieckert, A., Teichmann, A.-L., Drewelow, E., Kriechmayr, C., Piccoliori, G., Woodham, A., & Sönnichsen, A. C. (2019) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocz104 · Cited by 35
“Interestingly, GPs did not rate reimbursement as important, though complaints about insufficient reimbursement for caring for multimorbid older patients were brought up in other studies.(4,35) One has to note though that time and reimbursement are closely linked, as increased reimbursement could enable GPs to take mor…”
BackgroundPunt, M., Dalefield, B., Grigar, D., Blassnigg, M., Drayson, H., Rogers, H., Barber, J. F., Vines, J., Bedworth, J., Zilberg, J., et al. (2013) · British medical journal · doi:10.1162/leon_r_00670 · Cited by 22
“15; 61 mmHg trials) versus usual care.(26) Of particular importance, QI strategies that allowed pharmacists and specialist nurses to make independent changes to drug therapies were found to be most effective.”
BackgroundMethodResultInfluentialCaçador, C., Teixeira-Lemos, E., Oliveira, J., Pinheiro, J., Teixeira-Lemos, L., & Ramos, F. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19052637 · Cited by 21
“Previous studies had highlighted the same inappropriate exposure to benzodiazepines in institutionalized older adults, with rates reaching 30% [17,39].”
BackgroundA complex intervention for multimorbidity in primary care: A feasibility study
Birke, H., Jacobsen, R., Jønsson, A. B. R., Guassora, A. D., Walther, M., Saxild, T., Laursen, J. T., Vall-Lamora, M. H. D., & Frølich, A. (2020) · Journal of Comorbidity · doi:10.1177/2235042x20935312 · Cited by 23
“In other studies, taking additional time, involving patients, and improving information sharing were also important factors in care for patients with multimorbidity.(8,29,30)”
BackgroundLau, S., Lun, P., Ang, W., Tan, K. T., & Ding, Y. Y. (2020) · BMC Geriatrics · doi:10.1186/s12877-020-01766-7 · Cited by 23
Uptake of Preventive Services Among Patients With and Without Multimorbidity
Ukhanova, M., Tillotson, C., Marino, M., Huguet, N., Quiñones, A. R., Hatch, B., Schmidt, T. D., & DeVoe, J. (2020) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2020.04.019 · Cited by 19
Giguère, A., Lawani, M., Fortier-Brochu, É., Carmichael, P., Légaré, F., Kröger, E., Witteman, H., Voyer, P., Caron, D., & Rodríguez, C. (2018) · Trials · doi:10.1186/s13063-018-2697-1 · Cited by 19
Lauvergeon, S., Mettler, D., Burnand, B., & Peytremann-Bridevaux, I. (2015) · Health Expectations · doi:10.1111/hex.12013 · Cited by 19
Byszewski, A., Lemay, G., Molnar, F., Azad, N., & McMartin, S. E. (2011) · Journal of Osteoporosis · doi:10.4061/2011/404969 · Cited by 19
“The role of Osteoporosis Nurse Specialists has been recognized to play an important role in identifying patients at risk [17].”
BackgroundUpshur, R., Wang, L., Moineddin, R., Nie, J., & Tracy, C. (2012) · doi:10.5750/ijpcm.v2i4.315 · Cited by 18
Akande-Sholabi, W., Ajilore, C. O., & Ilori, T. (2023) · BMC Primary Care · doi:10.1186/s12875-023-01990-1 · Cited by 17
“This finding is similar to previously reported study [26].”
ResultRoot Cause Analysis of Ambulatory Adverse Drug Events That Present to the Emergency Department
Gertler, S. A., Coralic, Z., López, A., Stein, J. C., & Sarkar, U. (2014) · Journal of Patient Safety · doi:10.1097/pts.0000000000000072 · Cited by 14
“Previous work has suggested that disease-specific guidelines may put patients with multiple morbidities at risk of adverse events.(23,24) This case also involves warfarin, a medication that is not listed in the 2012 Beers Criteria for potentially inappropriate medicines in the elderly.”
BackgroundRhetoric and argumentation: how clinical practice guidelines think
Fuller, J. (2013) · Journal of Evaluation in Clinical Practice · doi:10.1111/jep.12037 · Cited by 29
“A qualitative study of primary care clinicians’ experiences with treatment decision making for older persons with multiple chronic conditions in the United States revealed variability in beliefs among participants regarding the benefits of guideline-directed care and the relevance of the evidence base for older patien…”
Influence of Patient Age and Comorbid Burden on Clinician Attitudes Toward Heart Failure Guidelines
Steinman, M. A., Sudore, R. L., Peterson, C. A., Harlow, J. B., & Fried, T. R. (2012) · The American Journal of Geriatric Pharmacotherapy · doi:10.1016/j.amjopharm.2012.04.003 · Cited by 16
Self-citationZhou, X., Han, L., Farmer, A. A., Yao, M., Yu, X., Yan, M., Wu, L., & Xu, Z. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-095063 · Cited by 19
“18 Barriers to accessing comprehensive patient information frequently force them to make decisions with incomplete data, further exacerbating their sense of inadequacy.”
Understanding Clinical Complexity the Hard Way: A Primary Care Journey.
Upshur, R. (2016) · Healthcare Quarterly · doi:10.12927/hcq.2016.24695 · Cited by 16
“Similarly Fried et al. (2011) in a study of primary care physicians’ experiences of caring for older patients with multimorbidity identified the following five themes:”
BackgroundLundby, C., Graabæk, T., Ryg, J., Søndergaard, J., Pottegård, A., & Nielsen, D. (2019) · The gerontologist · doi:10.1093/geront/gnz116 · Cited by 15
Grant, R. W., Lyles, C. R., Uratsu, C. S., Vo, M., Bayliss, E. A., & Heisler, M. (2019) · The Annals of Family Medicine · doi:10.1370/afm.2352 · Cited by 17
Hansen, C. R., Byrne, S., O’Mahony, D., Kearney, P. M., & Sahm, L. J. (2018) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-018-2578-2 · Cited by 18
Romskaug, R., Molden, E., Straand, J., Kersten, H., Skovlund, E., Pitkälä, K. H., & Wyller, T. B. (2017) · Trials · doi:10.1186/s13063-017-1900-0 · Cited by 14
“Because most GPs attain limited experience in handling complex health states, they may be reluctant to change medications initiated by hospital specialists [20].”
BackgroundThe Future of Gero-Oncology Nursing.
Kagan, S. (2016) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2015.11.008 · Cited by 15
Luijks, H., Grauw, W. J. D., Bor, J. H., van Weel, C., Lagro-Janssen, A. L. M., Biermans, M. C. J., & Schermer, T. R. (2015) · npj Primary Care Respiratory Medicine · doi:10.1038/npjpcrm.2015.32 · Cited by 9
Armstrong, N., & Swinglehurst, D. (2018) · Family Practice · doi:10.1093/fampra/cmy022 · Cited by 14
Anderson, K., Freeman, C. R., Rowett, D., Burrows, J., Scott, I., & Rigby, D. (2015) · doi:10.1002/jppr.1164 · Cited by 14
La multimorbilidad vista desde la perspectiva de los profesionales de atención primaria
Nuño-Solinís, R., Elorriaga, K. P., Pereira, C. R., Martínez, A. G., & Gabilondo, M. A. (2014) · Atención Primaria · doi:10.1016/s0212-6567(14)70059-9 · Cited by 14
Bower, P., Hann, M., Rick, J., Rowe, K., Burt, J., Roland, M. O., Protheroe, J., Richardson, G. A., & Reeves, D. (2013) · Journal of Health Services Research & Policy · doi:10.1177/1355819613492148 · Cited by 14
Damiaens, A., Hecke, A. V., de Lepeleire, J., & Foulon, V. (2022) · BMC Geriatrics · doi:10.1186/s12877-022-02773-6 · Cited by 13
The analysis of the use of potentially inappropriate medications in elderly in the Slovak Republic
Jankyova, S., Rubintova, D., & Foltanova, T. (2019) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-019-00944-x · Cited by 13
“As described elsewhere, primary care clinicians struggle with the uncertainties of applying disease-specific guidelines to their older patients with multiple conditions [42, 43].”
BackgroundAn integrative review of drug utilization by the elderly in primary health care
de Oliveira, L. P. B. A., & dos Santos, S. M. A. (2016) · Revista da Escola de Enfermagem da USP · doi:10.1590/s0080-623420160000100021 · Cited by 17
“At least seven other articles emphasized the sovereign role played by physicians in drug therapy(27-28,33,76-79).”
Peart, A., Lewis, V., Barton, C., & Russell, G. (2020) · Journal of Clinical Nursing · doi:10.1111/jocn.15243 · Cited by 12
Senft, J., Wensing, M., Poß-Doering, R., Szecsenyi, J., & Laux, G. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-033325 · Cited by 12
Audétat, M., Sader, J., Notari, S. C., Ritz, C., Fon, N. C., Maisonneuve, H., Blondon, K., & NENDAZ, M. R. (2019) · Health · doi:10.4236/health.2019.1110103 · Cited by 15
“1110103 1340 Health including prioritization of the doctor’s or the patient’s agenda [3] [24], avoidance of decision-making [19], solely drawing on one’s own personal experience [24], or using additional investigations to support a decision [25].”
BackgroundPatient-Defined Visit Priorities in Primary Care: Psychosocial Versus Medically-Related Concerns
Santo, E., Vo, M., Uratsu, C. S., & Grant, R. W. (2019) · Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2019.04.180380 · Cited by 12
Are Physicians Decisions Affected by Multiple Nonclinical Factors?
Schattner, A. (2014) · Internal Medicine Open Access · doi:10.4172/2165-8048.1000152 · Cited by 10
“The unprecedented advances in biological insight and medical high-technology are yielding sophisticated capabilities and increasing options [60] – but patients are also older, more complex and overmedicated [61].”
BackgroundThe Prevalence of Periodontitis Among US Adults with Multimorbidity Using NHANES Data 2011–2014
O’Dwyer, M. C., Furgal, A. K. C., Furst, W., Ramakrishnan, M., Capizzano, J. N., Sen, A., & Klinkman, M. S. (2023) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2022.220207r1 · Cited by 20
“11,12 With Chronic Illness, Comes Increasing Health Care Costs and Related Burdens 9 Periodontitis is associated with an array of chronic medical conditions, including both type 1 and type 2 diabetes, 13 in fl ammatory bowel disease, 14 and cardiovascular disease 4 — to name just a few.”
BackgroundDevelopment of an international comorbidity education framework
Lawson, C. A., Pati, S., Green, J., Messina, G., Strömberg, A., Nante, N., Golinelli, D., Verzuri, A., White, S. J., Jaarsma, T., et al. (2017) · Nurse Education Today · doi:10.1016/j.nedt.2017.05.011 · Cited by 14
Foebel, A. D., Liperoti, R., Gambassi, G., Gindin, J., Israel, J. B., Bernabei, R., & Onder, G. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.12.085 · Cited by 14
Ogawa, T., Fujimoto, S., Omon, K., Ishigaki, T., & Morioka, S. (2023) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-023-02208-1 · Cited by 11
“[21] reported that having multiple conditions one of the factors that make it difficult for older patients to be involved in decision-making.”
BackgroundLovett, R., Bonham, M., Benavente, J. Y., Hosseinian, Z., Byrne, G. J., Diaz, M. V., Bass, M., Yao, L., Andrei, A., Batio, S., et al. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-080101 · Cited by 9
Amano, H., Fujimoto, K., Fujimori, M., Saka, N., Nomura, K., & Tanihara, S. (2020) · Acta Medica Okayama · doi:10.18926/amo/57951 · Cited by 9
“[23], it is important to carefully consider the benefits and risks involved in drug selection strategies as well as strategies to reduce the drug intakes of elderly people.”
BackgroundPardo, P., García, A., & Cortés, J. (2016) · Gaceta Sanitaria · doi:10.1016/j.gaceta.2016.04.008 · Cited by 9
“Cruz Roja Mental previo 1,6 (1,5) 1,5 (1,5) 0,84”
InfluentialDoctors’ understanding of individualisation of drug treatments: a qualitative interview study
Denford, S., Frost, J., Dieppe, P. A., & Britten, N. (2013) · BMJ Open · doi:10.1136/bmjopen-2013-002706 · Cited by 10
Selim, A. J., Fincke, B., Rogers, W., Qian, S., Selim, B., & Kazis, L. (2013) · Journal of Managed Care Pharmacy · doi:10.18553/jmcp.2013.19.2.132 · Cited by 9
“Future efforts should focus on identifying factors that account for plan variation in the prescription of guideline-recommended medications and on remedial quality improvement activities (standing orders, reminder systems, critical care pathways, algorithms, audits).(25,26) The observed variation across MA plans in gu…”
BackgroundMechili, E. A., Saliaj, A., Xhindoli, J., Bucaj, J., Sifaki-Pistolla, D. I., Peto, E., Zahaj, M., & Chatzea, V. (2021) · Health & Social Care in the Community · doi:10.1111/hsc.13411 · Cited by 7
Rausch, C., & Hoffmann, F. (2020) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-020-02859-3 · Cited by 8
“This may lead to varying treatment approaches, including the initiation of new anti-dementia medications at the end of life [24, 47, 48].”
BackgroundPel‐Littel, R. E., Hofman, C. S., Yu, L., Metzelthin, S., Leeuwis, F. H., Blom, J. W., Buurman, B. M., & Minkman, M. M. N. (2019) · PLoS ONE · doi:10.1371/journal.pone.0225344 · Cited by 10
Thomas-Purcell, K. B., Jacobs, R., Seidman, T. L., Acevedo, A., Waldrop-Valverde, D., & Ownby, R. (2019) · Clinical Interventions in Aging · doi:10.2147/cia.s193215 · Cited by 8
“More empirical evidence, clear guidelines, and effective approaches should be available to improve quality of care.(6) By itself, providing the highest quality of care will not guarantee improved health outcomes for people with MCCs.”
BackgroundWillingness to Change Medications Linked to Increased Fall Risk: A Comparison between Age Groups
Haddad, Y. K., Karani, M. V., Bergen, G., & Marcum, Z. (2018) · Journal of The American Geriatrics Society · doi:10.1111/jgs.15696 · Cited by 8
“Providers also reported concerns about applying guideline-directed care in older adults due to the difficulty of performing risk stratification for individual patients and balancing the benefits and harms to older patients.(16) Better tools are needed to quantify risks and benefits of medication use in older adults an…”
BackgroundKosirova, S., Urbánková, J., Klimas, J., & Foltanova, T. (2023) · BMC Geriatrics · doi:10.1186/s12877-023-04260-y · Cited by 7
“GPs are usually responsible for long-term followup and repeat prescriptions [55], while geriatricians are skilled in the treatment of physiological and pathological changes connected with ageing [56].”
BackgroundGiunta, S., Butow, P. N., Juraskova, I., Sharpe, L., Ferguson, E. M., & Laidsaar‐Powell, R. (2022) · Patient Education and Counseling · doi:10.1016/j.pec.2022.08.019 · Cited by 7
Audétat, M., Notari, S. C., Sader, J., Ritz, C., Fassier, T., Sommer, J., NENDAZ, M. R., & Fon, N. C. (2021) · BMC Medical Education · doi:10.1186/s12909-020-02459-w · Cited by 8
“But since physicians have often developed their clinical expertise in a tacit and informal way [3, 47, 48], it may be difficult for them to supervise and teach their trainees in a targeted and specific manner.”
BackgroundGaster, C., Hofheinz, R., & Burkhardt, H. (2020) · Oncology Research and Treatment · doi:10.1159/000512593 · Cited by 7
Surgical Emergencies in Patients with Significant Comorbid Diseases
Blank, J. J., Shiroff, A. M., & Kaplan, L. J. (2023) · Surgical Clinics of North America · doi:10.1016/j.suc.2023.06.003 · Cited by 10
Christopher, C. M., Cheong, W. L., Blebil, A. Q., Bhuvan, K. C., Alex, D., Ibrahim, M. I. M., & Ismail, N. (2023) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2023.105007 · Cited by 9
Deprescribing practice in a resource‐limited setting: Healthcare providers’ insights
Tegegn, H. G., Gebresillassseie, B. M., Erku, D., Elias, A., Yabeyu, A., & Ayele, A. A. (2020) · International journal of clinical practice · doi:10.1111/ijcp.14356 · Cited by 6
Fighting the Enemy Within? Challenging Minor Principles of Professionalism in Care and Welfare
Trappenburg, M. J., & Noordegraaf, M. (2018) · Professions and Professionalism · doi:10.7577/pp.2265 · Cited by 6
“Fried, Tinetti, and Iannone (2011) did a focus group study among primary care clinicians and found that clinicians worry about the detrimental effects of guidelines on patients with multi-morbidity.”
BackgroundVermunt, N. P. C. A., Westert, G. P., Rikkert, M. G. M. O., & Faber, M. J. (2018) · Scandinavian Journal of Primary Health Care · doi:10.1080/02813432.2018.1426149 · Cited by 6
Backman, R., Weber, P., Turner, A. M., Lee, M. G., & Litchfield, I. J. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-016713 · Cited by 4
“There are also implications for clinicians who struggle to balance the requirements of several guidelines for multimorbid patients, hindered by the lack of outcome data.(18) One significant consequence of following multiple guidelines is the concurrent prescribing of multiple medications.”
BackgroundLeBlanc, T. W., Howson, A., Turell, W., Sheldon, P., Locke, S. C., Tuchman, S. A., Gasparetto, C., Kaura, S., Khan, Z., & Abernethy, A. P. (2016) · Current Oncology · doi:10.3747/co.23.3298 · Cited by 6
Komorbidität in Leitlinien: Ist-Zustand, epidemiologische Modelle und Expertenmeinung im Vergleich
Blozik, E., Dubben, H.-H., Wagner, H.-O., & Scherer, M. (2014) · Zeitschrift für Evidenz Fortbildung und Qualität im Gesundheitswesen · doi:10.1016/j.zefq.2014.02.001 · Cited by 6
Japelj, N., Knez, L., Petek, D., & Horvat, N. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1468750 · Cited by 5
Pasciak, W., Berg, D. N., Cherlin, E. J., Fried, T. R., & Lipska, K. J. (2021) · BMC Geriatrics · doi:10.1186/s12877-021-02268-w · Cited by 10
“In previous qualitative studies, healthcare professionals cited concerns regarding the suitability of selfmanagement for patients they deemed not capable [37, 38].”
BackgroundSelf-citationRuangritchankul, S., Peel, N., Hanjani, L. S., & Gray, L. (2020) · Clinical Interventions in Aging · doi:10.2147/cia.s252432 · Cited by 5
Grimsmo, A. (2018) · Tidsskrift for Omsorgsforskning · doi:10.18261/issn.2387-5984-2018-02-03 · Cited by 5
Holm, A., Berland, A., & Severinsson, E. (2016) · Open Journal of Nursing · doi:10.4236/ojn.2016.610086 · Cited by 5
“Healthcare professionals seem to struggle to obtain suitable guidelines pertaining to caring for patients with multimorbidity while responding to patient needs [54] [55].”
BackgroundPel-Littel, R., van Rijn, M., Vermunt, P., van Weert, J. V., Minkman, M., ter Riet, G., Reimer, W. J., & Buurman, B. (2018) · Journal of Aging Research and Lifestyle · doi:10.14283/jarcp.2018.5 · Cited by 5
“Health care professionals often lack routine practices in eliciting older persons’ preferences, and older persons often lack the confidence to express them (10, 15-17).”
Practice Inquiry: Uncertainty Learning in Primary Care Practice
Sommers, L. S. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6812-7_9 · Cited by 5
Lubbe, A. L., Schellekens, J., Pol, M., Groen, W., Buurman, B., Hertogh, C., & van Rijn, M. (2024) · European Geriatric Medicine · doi:10.1007/s41999-024-01065-z · Cited by 4
Wang, J., Leung, L. B., JACKSON, N. J., McClean, M., Rose, D. E., Lee, M. L., & Stockdale, S. E. (2024) · BMC Family Practice · doi:10.1186/s12875-024-02410-8 · Cited by 7
Waldron, C., Hughes, J., Wallace, E., Cahir, C., & Bennett, K. (2022) · HRB Open Research · doi:10.12688/hrbopenres.13580.2 · Cited by 4
“Patients’ willingness, and ability to be involved in decision making varied widely in the included articles 29,30,32,35,37,40,54,69,71 .”
InfluentialTurabián, J. L., & Franco, B. P. (2014) · Medicina de Familia SEMERGEN · doi:10.1016/j.semerg.2014.09.011 · Cited by 4
Impediments to deprescription in Brazil: overview from a panel of geriatrics experts
Teixeira, J. J. M., Provin, M. P., Freitas, M. P., Santana, F. R., Pedatella, M., & Rocha, L. E. D. A. (2022) · Geriatrics Gerontology and Aging · doi:10.53886/gga.e0220002 · Cited by 4
Everall, A. C., Cadel, L., Lofters, A., Packer, T. L., Hitzig, S. L., Patel, T., Cimino, S. R., & Guilcher, S. J. T. (2020) · Disability and Rehabilitation · doi:10.1080/09638288.2020.1799249 · Cited by 4
“However, healthcare providers face multiple challenges in optimizing medication management including difficulties balancing their goals and priorities with those of patients [25].”
BackgroundRygiel, K. (2019) · EMJ Innovations · doi:10.33590/emjinnov/10313381 · Cited by 3
Physicians' Non‐Uniform Approach to Prescribing Drugs to Older Patients – A Qualitative Study
Christensen, L. D., Petersen, J., Andersen, O., & Kaae, S. (2017) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12837 · Cited by 3
Potentially Inappropriate Drug Prescribing and the "Never Change a Winning Team" Principle.
Onder, G., Nobili, A., & Marengoni, A. (2016) · The journals of gerontology. Series A, Biological sciences and medical sciences · doi:10.1093/gerona/glw115 · Cited by 3
Rapid Synthesis: Identifying Optimal Treatment Approaches for People with Multimorbidity in Ontario
Gauvin, F., Wilson, M. G., & Álvarez, E. (2013) · MacSphere (McMaster University) · doi:10.71548/2975 · Cited by 3
“tension between delivering care to meet quality targets and fulfilling the patient's expectations;(68;69) 3.”
InfluentialLinsky, A. M., & Simon, S. R. (2012) · BMC Research Notes · doi:10.1186/1756-0500-5-619 · Cited by 3
“Additionally, explicit discussions may enable providers to better reconcile known conflicts between what they believe is clinically best and what the patient perceives as important [13,14].”
BackgroundGiokas, K., Katrakazas, P., & Koutsouris, D. (2016) · Advances in healthcare information systems and administration book series · doi:10.4018/978-1-4666-9861-1.ch003 · Cited by 1
Charette, S. L., Garcia, M. B., & Reuben, D. B. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-420123-1.00001-0 · Cited by 5
Ando, T., Sasaki, T., Fujikawa, H., Haruta, J., & Arai, Y. (2025) · Scientific Reports · doi:10.1038/s41598-025-18178-5 · Cited by 2
“General practitioners (GPs) have also reported challenges in managing the increasing treatment burden from multiple specialist referrals, including difficulties in coordinating care across specialties, ensuring consistent communication, and managing overlapping or conflicting treatment plans 12 .”
Alsalemi, N., Sadowski, C., Kilpatrick, K., Elftouh, N., Houle, S. J. D., & Lafrance, J. (2024) · BMC Health Services Research · doi:10.1186/s12913-024-10568-1 · Cited by 2
The role of INTERCheckWEB digital innovation in supporting polytherapy management
Foglia, E., Ferrario, L. B., Garagiola, E., Asperti, F., Mazzone, A., Gatti, F., Varalli, L., Ponsiglione, C., & Cannavacciuolo, L. (2023) · Scientific Reports · doi:10.1038/s41598-023-32844-6 · Cited by 3
“Additionally, the more the clinicians know about guidelines and protocols, the more the clinicians learn about the potential development of DDIs or adverse events, leading to a possible change of the current patient’s therapy 55 .”
Backgroundvan Peet, P. G., Gussekloo, J., den Elzen, W. P. J., Blom, J. W., de Waal, M. W. M., & de Ruijter, W. (2015) · Scandinavian Journal of Primary Health Care · doi:10.3109/02813432.2015.1117281 · Cited by 3
“In general, vulnerable patients might receive fewer preventive drugs than fit older people [21,22], although, ultimately, vulnerability should not be viewed as a reason to withhold care, but rather as a means of delivering it in a more patient-centred fashion [23] For secondary cardiovascular preventive medication thi…”
BackgroundPatterns and Stability over Time of Older Adults’ Diabetes-related Beliefs
Grzywacz, J. G., Arcury, T., Nguyễn, H. T., Saldana, S. J., Ip, E., Kirk, J., Bell, R., & Quandt, S. (2014) · Health behavior and policy review · doi:10.14485/hbpr.1.2.3 · Cited by 2
To Fall Is Human: Falls, Gait, and Balance in Older Adults
Harris, P. F., & Garcia, M. B. (2016) · Springer eBooks · doi:10.1007/978-3-319-28137-7_5 · Cited by 2
Everybody Knows: A Unitary Theoretical Framework or a Pluralist Kaleidoscope?
Roche, J. (2026) · Postdigital Science and Education · doi:10.1007/s42438-026-00661-5 · Cited by 1
The geriatric gap: the absence of geriatric medicine in postgraduate medical training in Poland
Kupis, R. W., Grot-Wereda, A., Perera, I., & Piotrowicz, K. (2026) · European Geriatric Medicine · doi:10.1007/s41999-026-01452-8 · Cited by 2
“They may root from both internal and external factors, including conflicts in personality between personnel and patients, possessed experience, and legal regulations, to name a few [15, 16].”
Levati, E., Zazzara, M. B., Iurlaro, A., Marzetti, E., Calvani, R., Pahor, M., Picca, A., Tosato, M., Landi, F., Bernabei, R., et al. (2025) · European Geriatric Medicine · doi:10.1007/s41999-025-01266-0 · Cited by 1
“Indeed, in both LIFE and SPRINTT, decisions on whether continuing or discontinuing medications were delegated to the participant’s primary care physician [31].”
Metadata
- Authors
- Fried, T. R., Tinetti, M. E., & Iannone, L.
- Affiliations
- Yale University (US)
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2010-09-13
- Volume
- 171
- Issue
- 1
- Pages
- 75-80
- ISSN
- 0003-9926 (ISSN-L)
- PMC
- PMC3021478
- OpenAlex
- W2012018261
- Cited by
- 236
- References
- 28
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 7 · 2023: 11 · 2022: 12 · 2021: 10 · 2020: 15 · 2019: 24 · 2018: 15 · 2017: 22 · 2016: 22 · 2015: 15 · 2014: 23 · 2013: 18 · 2012: 24
- FWCI
- 12.37
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Yale University (P30AG21342)
- National Institutes of Health
- National Institute on Aging (K24AG028443, P30 AG21342, P30AG021342)
- Topics
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Health Professions › General Health Professions › Patient-Provider Communication in Healthcare
- Keywords
- treatment decision-making, older adults, multimorbidity, primary care providers, guideline-directed care, medication adherence, benefits and harms, shared decision-making, barriers to decision-making, reimbursement, clinician beliefs
- MeSH terms
- Workforce, Adult, Aged, Chronic Disease, Connecticut, Decision Making, Female, Goals, Hospitals, University, Humans, Male, Middle Aged, Nurse Practitioners, Patient Compliance, Practice Patterns, Physicians', Physician Assistants, Primary Health Care, Residence Characteristics, United States, Comorbidity, Focus Groups, Narration, Qualitative Research, Medication Adherence, Physicians, Primary Care
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